John E. Jesseph

Pseudocyst of the pancreas. A review of fifty cases

Abstract In fifty cases of pancreatic pseudocyst the diagnosis was established by autopsy in five cases and operation in forty-five cases. Alcoholism was identified as the most common etiologic factor. The best physical or laboratory evidence of pseudocyst was displacement of the stomach or duodenum in 86 per cent of forty-four patients examined by barium studies. External drainage with a catheter, the most common method of surgical management, was associated with low morbidity. Delay in operation appeared responsible for a number of complications, some of which were fatal. Eight of the fifty patients died, with hemorrhage being the primary cause of death in seven.

Decreased gastric secretory activity following injection of lignin sulfonates.

Summary Solutions of calcium lignin sulfonates injected immediately after ligation in the Shay rat (20 mg/100 g rat weight) afforded pronounced protection against ulceration as compared with controls. The same material given per osalso protected Shay rats against ulceration, probably by a different mechanism.

The effect upon free hydrochloric acid production of Heidenhain pouches with variation in size and position of a gastrojejunostomy stoma.

Abstract Under the conditions of this experimental study we found that there was only a moderate increase in Heidenhain pouch secretion following a low antral gastrojejunostomy if the stoma was constructed 2 cm. in diameter. If, however, the gastrojejunostomy stoma was constructed 4 cm. in diameter, there was a marked increase. The average increase in secretion of free hydrochloric acid from the Heidenhain pouch when stimulated by a 2 cm. diameter gastrojejunostomy stoma was 43.3 per cent. For a 4 cm. stoma the similar average was 144.9 per cent, or over three times as much. If the 34.3 per cent increase produced by multiple operations alone is considered, this difference is even greater.