Everett J. Schmitz

Gastric Secretion in Heidenhain Pouches Following Section of Vagus Nerves to Main Stomach

Conclusions In the dog, section of the vagus nerves to the main stomach causes a marked increase in the quantitative 24 hour acid secretion from Heidenhain pouches.

Heidenhain Pouch Secretory Response as Affected by Gastrojejunostomy to the Main Stomach.

Conclusion Under the conditions of this experiment, gastrojejunostomy of the main stomach of Heidenhain pouch dogs results in a significant rise in free HO secretion from the pouch.

Experimental Vascular Grafts

1 National Heart Institute Trainee. 2 Postdoctorate Research Fellow, U. S. Public Health Service. 3 Instructor, Department of Surgery, and Fellow, American Cancer Society. 4 Instructor in Surgery. 5 Damon Runyon Cancer Fellow, Department of Surgery, University of Washington School of Medicine, 1950-1952; at present, Captain, M.C., U. S. Army Medical School, Washington, D. C. 6 Formerly Instructor in Surgery; at present in private practice, Wilmington, N. C. 7 Research Chemist and Head of the Surgical Chemistry Laboratory. 8 Associate Professor of Surgery, University of Washington School of Medicine. 9 Professor of Surgery and Executive Officer of Department of Surgery, University of Washington School of Medicine. From the Department of Surgery, University of Washington School of Medicine, Seattle, Washington. This was aided in part by a grant from the Division of Research Grants and Fellowships, National Heart Institute, Bethesda, Maryland, (H-1136), by a Grant from Initiative 171 funds of the State of Washington, and the Vadheim Surgical Research Fund of the Department of Surgery. This report represents a further study of the problems proposed in a previous communication, by Kanar et al. (1), who compared five fresh autogenous vein grafts implanted into the thoracic aortas of growing pigs with five similar grafts surrounded by crystalline dicetyl phosphate. Their conclusions were that: 1. Ve-

A New Operative Preparation for Production of Peptic Ulcer in the Dog

Summary 1. A method for production of experimental peptic ulcer in dogs is presented. Its advantages are reliability, simplicity of post-operative care, rapidity of ulcer development, and survival of animals in good nutritional condition, thus allowing prolonged study in protected animals. The ulcers are produced without extraneous stimulation. 2. Four groups of animals were studied. The effect of vagotomy alone, antrumectomy alone, and vagotomy combined with antrumectomy are evaluated as to incidence of ulcer and period of survival (an indication of the time required for development of ulcer).