Jonas Grossenbacher

Harnessing the damping properties of materials for high-speed atomic force microscopy

The success of high-speed atomic force microscopy in imaging molecular motors, enzymes and microbes in liquid environments suggests that the technique could be of significant value in a variety of areas of nanotechnology. However, the majority of atomic force microscopy experiments are performed in air, and the tapping-mode detection speed of current high-speed cantilevers is an order of magnitude lower in air than in liquids. Traditional approaches to increasing the imaging rate of atomic force microscopy have involved reducing the size of the cantilever, but further reductions in size will require a fundamental change in the detection method of the microscope. Here, we show that high-speed imaging in air can instead be achieved by changing the cantilever material. We use cantilevers fabricated from polymers, which can mimic the high damping environment of liquids. With this approach, SU-8 polymer cantilevers are developed that have an imaging-in-air detection bandwidth that is 19 times faster than those of conventional cantilevers of similar size, resonance frequency and spring constant.

Curved Holographic Combiner for Color Head Worn Display

A volume hologram recorded with a lens array is proposed as a color transflective screen for Head Worn Display (HWD) systems. Design, fabrication as well as proof of concept are reported. Light from a single MEMS-based projector is efficiently diffracted towards the eye with an angular spread given by the numerical aperture of the lenses forming the lens array. Using a dual-focus contact lens, full color high-resolution images are added to the HWD users normal vision. A full color system with a 55 degrees lateral field of view is demonstrated. This screen offers the possibility for small footprint and large field of view HWDs.

Cytotoxicity evaluation of polymer-derived ceramics for pacemaker electrode applications

Ceramics are known to be chemically stable, and the possibility to electrically dope polymer-derived ceramics makes it a material of interest for implantable electrode applications. We investigated cytotoxic characteristics of four polymer-derived ceramic candidates with either electrically conductive or insulating properties. Cytotoxicity was assessed by culturing C2C12 myoblast cells under two conditions: by exposing them to material extracts and by putting them directly in contact with material samples. Cell spreading was optically evaluated by comparing microscope observations immediately after the materials insertion and after 24 h culturing. Cell viability (MTT) and mortality (LDH) were quantified after 24-h incubation in contact with the materials. Comparison was made with biocompatible positive references (alumina, platinum, biocompatible stainless steel 1.4435), negative references (latex, stainless steel 1.4301) and controls (no material present in the culture wells). We found that the cytotoxic properties of tested ceramics are comparable to established reference materials. These ceramics, which are reported to be very stable, can be microstructured and electrically doped to a wide range of conductivity and are thus excellent candidates for implantable electrode applications including pacemakers.

Rapid carbon nanotubes suspension in organic solvents using organosilicon polymers

A strategy for a simple dispersion of commercial multi-walled carbon nanotubes (MWCNTs) using two organosilicones, polycarbosilane SMP10 and polysilazane Ceraset PSZ20, in organic solvents such as cyclohexane, tetrahydrofuran (THF), m-xylene and chloroform is presented. In just a few minutes the combined action of sonication and the presence of Pt(0) catalyst is sufficient to obtain a homogeneous suspension, thanks to the rapid hydrosilylation reaction between SiH groups of the polymer and the CNT sidewall. The as-produced suspensions have a particle size distribution <1μm and remain unchanged after several months. A maximum of 0.47 and 0.50mg/ml was achieved, respectively, for Ceraset in THF and SMP10 in chloroform. Possible applications as polymeric and ceramic thin films or aerogels are presented.

SU-8 C-MEMS as candidate for long-term implantable pacemaker micro electrodes

This paper presents the first successful implantation of electrically conductive SU-8 C-MEMS electrodes able to pace muscle tissue in an animal model. The electrochemical characterizations of the ceramic electrodes show comparable values to state of the art platinum (Pt) metal electrodes. The micro-fabricated pacemaker electrodes were successfully tested in vitro (cardiomyocyte), in vivo (rat peripheral muscle) and ex vivo (explanted rat heart) pacing experiments. Short term C-MEMS implantation assays show lower levels of fibrosis compared to conventional electrodes.