Jorge Mali Junior

Gastroplastia vertical com bandagem em y-de-roux: análise de resultados

BACKGROUND: To analyze prospectively the results of patients submitted to vertical banded gastroplasty-Roux-en-Y gastric bypass at the Hospital Universitario, Universidade Estadual de Londrina. METHODS: We analized mortality, morbidity and weight loss of 250 consecutive patients with no previous bariatric surgery who were submitted to a combination of vertical banded gastroplasty and Roux-en-Y gastric bypass. Patients were followed up at least for one year. They had a mean body mass index of 46 Kg/M2. RESULTS: The incidence of complications that required reoperation was 2%. No deaths ocurred in the present study. After a follow up of one to three years we noticed an average decrease of 37.5% in the pre-operative weight. In addition to the weight loss we detected a great improvement in the comorbidities and in some cases total control of the desease related to the obesity.CONCLUSIONS: Vertical banded gastroplastic Roux-en-Y gastric bypass is effective in promoting weight loss in morbid obese, and had a low mortality and morbidity.

Evolução ponderal oito anos após a derivação gástrica em Y-de-Roux

OBJECTIVE To evaluate the effectiveness of banded Roux-en-Y gastric bypass in promoting weight loss after an eight-year follow-up. METHODS Two hundred and eleven obese patients underwent Roux-en-Y gastric bypass with banding by the same surgical team. The study design was longitudinal, prospective and descriptive. The analysis of weight decrease in the postoperative period was based on the loss of excess weight in percentage and BMI. Failure was considered when patients lost <50% of excess weight. RESULTS The loss of follow-up was 36.5%, therefore, 134 patients were included in this study. The loss of excess weight in global average rate in the postoperative period was: 67.6 ± 14.9% in the first year, 72.6 ± 14.9% in the second year, 69.7 ± 15.1% in fifth year and 66.8 ± 7.6 in eight years. Surgical treatment failure occurred in 15 patients (7.1%) over the period. CONCLUSION Banded Roux-en-Y gastric bypass was effective in promoting and sustaining weight loss in the long term, with low failure rates.

Estudo do padrão alimentar tardio em obesos submetidos à derivação gástrica com bandagem em Y- de- Roux: comparação entre homens e mulheres

BACKGROUND: To evaluate late meal patterns in patients after Roux-en-Y gastric bypass surgery and to compare sex gender differences. METHODS: From July 2006 to July 2007, patients from the outpatient Londrina Hospital State University - Digestive Surgery Section were evaluated after at least 12 months post-operatively. The patients were studied through a questionnaire, including demographic items about eating behavior, meal pattern, and frequency of vomiting and dumping symptoms. Statistical analysis was performed using Chi-square or Fischer test with significance requiring p<0.05. RESULTS: Data were collected from 116 patients, 95(78.4%) were women and 25(21.5%) were men. There were small differences when comparing women and men in eating behavior, meal pattern, frequency of vomiting and dumping symptoms and no statistical significance was found. Only the variables of fruits intake and somnolence were significantly more frequent in women. CONCLUSION: Applying the proposed questionnaire it was possible to know the late eating behavior and meal pattern of our patients. The intake of fruits was the unique item with statistical differences between genders.

Tratamento cirúrgico das estenoses da via biliar

BACKGROUND: Benign stricture of biliary tract (BSBT) are iatrogenic in about 95% of the cases. Although rare, its outcome is poor; therefore prevention is the best option. The objective of this study is to evaluate the surgical management and its results in BSBT. METHODS: We retrospectively analyzed 11 patients submitted to corrective surgery for BSBT at Hospital Universitario Regional do Norte do Parana, from July / 92 to December / 01. RESULTS: There were nine female patients and the mean age was 43.71 years old. Previous surgeries were classic cholecistectomies (81.8%) and videocholescistectomies (18.2%).The most frequent signs and symptoms were jaundice (64.3%), abdominal pain (64.3%) and fever (21.4). The diagnosis was confirmed by CPRE in 90.9% of the patients and CTP in 9.1%. According to Bismuth‘s classification, 18.2% of the patients were considered grade I, 45.4% grade II, 18.2% grade III and 18.2% grade IV. The corrective surgery for BSBT was choledochoduodenostomy in two cases of grade I, hepaticojejunostomy using a Roux-en-Y loop of jejunum in five cases of grade II, Hepp-Couinauds operations in two cases of grade III, hepaticojejunostomy with mucosal graft (Smiths technique) in two cases of grade IV. The postoperative complications were fistula (18.2%), death (18.2%), pneumonia (9.1%) and hemobilia (9.1%). CONCLUSION: Complexity of the surgical treatment requires prevention of injuries. Bile duct lesions repair should be considered as a specialists procedure and should be performed in a center with special interest in this disease.

Estudo da linfadenectomia radical comparada à linfadenectomia standard no tratamento cirúrgico do adenocarcinoma da papila de Vater

OBJECTIVE To evaluate the morbidity and mortality in patients undergoing surgical pancreatoduodenectomy (PD) in standard and radical lymphadenectomy for adenocarcinoma of papilla, analyzing the prognostic factors related to overall and disease-free survival. METHODS Were analyzed retrospectively from 1999 to 2007, in the Department of Abdominal and Pelvic Surgery (INCa-RJ), 50 cases of PD for adenocarcinoma of the duodenal papilla divided into two groups according to lymphadenectomy (group A: standard lymphadenectomy and group B: radical lymphadenectomy). RESULTS The median age was similar in both groups, as well as the distribution between the sex. In the comparison between the lymphadenectomies, only the number of lymph nodes resected (group A: 12.3 and group B: 26.5) and operative time (group A: 421 and group B: 474) were significantly different. There were no statistically significant differences in the two groups with respect to morbidity and mortality rate and length of hospitalization. The disease-free survival (group A: 35 months and group B: 51 months) and overall survival (group A: 38 months and group B: 53 months) was higher in the group of radical lymphadenectomy, but were not statistically significant. CONCLUSION In this study there were no cases of metastatic lymph nodes to other groups without nodal involvement of the pancreatic-duodenal lymph node chains (13, 17), suggesting a pattern of lymph node spread. Despite the radical lymphadenectomy present rates of disease-free survival and overall survival largest such data were not statistically significant. Further studies should be conducted to evaluate the real role of radical lymphadenectomy in adenocarcinoma of the duodenal papilla.

Emprego da anastomose pancreatojejunal tipo ducto-mucosa sem cateter transanastomótico em pâncreas de consistência mole e ducto fino: experiência inicial do Instituto Nacional de Câncer

BACKGROUND: Our goal is to report the morbimortality associated to the pancreatic reconstruction technique using duct-to-mucosa nonstented pancreatojejunostomy in soft pancreas and Wirsungs duct less than 3 mm. METHODS: We analyzed 16 consecutive patients submitted to DP with duct-to-mucosa pancreatojejunostomy technique in the Service of Abdominal-pelvic Surgery of NCI-Brazil. All patients had soft pancreatic texture and small pancreatic duct (< 3mm). RESULTS: From those 16 patients, eight were males, with an mean age of 55 years old. In the post-operative period one patient developed pancreatic fistula. There had been one death. CONCLUSION: We believe that duct-to-mucosa nonstented pancreatojejunostomy is possible in patients with pancreatic duct less than three mm and soft texture pancreas without increased morbimortality.

Tratamento do megaesôfago chagásico grau II por laparoscopia: experiência em 12 casos

BACKGROUND: Various techniques have been used for the surgical treatment of esophageal achalasia, however, the best results for non - advanced esophageal achalasia has been achieved by miotomy. Laparoscopy for non advanced esophageal achalasia have been showing similar results than convencional surgery, with the benefits of a minimally invasive procedure. The aim of this study was to analyze the results of laparoscopy Heller miotomy and Dor fundoplication for non - advanced esophageal achalasia. METHODS: Twelve patients with non - advanced esophageal achalasia submitted to laparoscopic Heller miotomy and Dor fundoplication from Jan/99 to Dec/01 were prospectively analised. RESULTS: All surgeries were completed by laparoscopy with no conversion. Nine patients were assymptomatic and tree presented dysphagia, regurgitation and heartburn, respectively. These patients had a median follow-up of 13.2 months (9-39). There were two cases of gastric perfuration and one case of esophageal perfuration but no deaths occured in this series. CONCLUSION: Based in this study, we could conclude that the Heller miotomy associated to the Dor fundoplication by laparoscopy has a low complication rate. Its use was effective and safe for esophageal achalasia. The surgery is perfectively performed by laparoscopy, with results similar to those of laparotomy, added to the benefits of minimally invasive surgery.

Gastroduodenopancreatectomia ampliada para tumores não periampulares

BACKGROUND: To evaluate the surgical morbimortality and the outcome of patients submitted to extended duodenopancreatectomy (DP) for nonperiampulary tumors. METHODS: A retrospective evaluation of 15 patients submitted to DP for nonperiampulary tumors was performed in the abdominal-pelvic surgery service of National Cancer Institute- Brazil, from 1990 to 2005. RESULTS: The histological types of primary tumors included adenocarcinoma of colon (n=9), gastric adenocarcinoma (n=3), gastrointestinal stromal tumors (n=2) and renal carcinoma (n=1). The average hospital length of stay was 13.5 days (6 to 36), the average operation time was 360 minutes, the hemotransfusion average volume was 307 ml, the ressected lymph nodes average number was 19, where 3 patients had positive lymph nodes. The average size of the tumor was 7.8cm (2.5 to 24), the surgical morbidity was 53%, the operative mortality was 6.6% (one patient) and the overall survival average was 38 months. CONCLUSION: The duodenopancreatectomy for nonperiampulary tumors is an procedure of exception and it must be considered only for selected patients.

Morbimortalidade relacionada à técnica de anastomose pancreática (ducto-mucosa x telescopagem) após cirurgia de Whipple

BACKGROUND: Pancreaticoduodenectomy has been used as a safe and appropriate surgical option in selected patients with malignant and benign disorders of the pancreas and periampullary region. Among the complications of the pancreatoduodenectomy, pancreatic anastomosis failure is the most important and sometimes fatal complication. According to recent reports, the incidence of leakage of pancreatic anastomosis after PD is high (between 5% and 25%). Our objectives were to analize the morbidity and mortality rates related to pancreatic anastomosis technique (duct-to-mucosa VS. telescopic) and to compare the results. METHODS: From January 1987 to December 2002, 64 patients underwent pancreaticoduodenal resection at Brazilian National Cancer Institute. Data were recorded retrospectively on all patients. Forty-two patients underwent pancreatojejunostomy duct-to-mucosa and the telescopic technique was performed in 22 patients. Statistical analyses were performed using the Fischers test. RESULTS: The pancreatic fistula rate after pancreatojejunostomy duct-to-mucosa and telescopic technique was 12% and 36%, respectively (p = 0.02). The operative mortality rate after duct-to-mucosa technique was 12% and 36% after pancreatojejunostomy telescopic (p = 0.4). CONCLUSIONS: The leakage rate was significantly lower in patients underwent to pancreatojejunostomy duct-to-mucosa, however an operative mortality rate was not significantly different between the two groups.

Gastroesophageal Reflux Disease: Pathophysiology

Gastroesophageal reflux disease (GERD) is a common disease with a variable prevalence ranging from 5 % in the Eastern population to 25 % in the West. Moreover, GERD incidence seems to be escalating.