José Sánchez del Río

Haemorrhagic cellulitis caused by Salmonella enteritidis

Soft tissue infections are rare manifestations of extra-intestinal salmonellosis and occur more frequently in immunocompromized patients [1–4]. We report haemorrhagic cellulitis in an immunosuppressed patient with sepsis caused by a non-typhoid Salmonella.

Multiple lentigines confined to resolving psoriatic plaques in a patient treated with adalimumab.

drug induced, (b) the result of the immunosuppressive action of adalimumab, because systemic immunosuppressants are reported to cause an increase in melanocyte activity, or (c) might simply be a postinflammatory hyperpigmentation. On the other hand, melanocytes may be involved in the psoriatic process in several ways: there have been several reports suggesting an association between chronic plaque psoriasis and vitiligo, and the absence of lentigines in psoriatic plaques has been presumed to be the result of selectively destroyed melanocytes by the psoriatic process [6] . The clinical implication of our finding is uncertain. Overall, careful surveillance will be required in those patients receiving biological treatments.

Epidemiología básica para dermatólogos

Resumen —La epidemiologia es la ciencia que estudia la frecuencia de las enfermedades. Los estudios epidemiologicos se dividen en dos grupos, el primero de ellos engloba los dirigidos a determinar la frecuencia de enfermedad y los segundos las asociaciones entre frecuencia y exposicion. Se revisan los conceptos basicos del primer grupo de estudios y se describe el segundo tipo con los errores que se presentan mas frecuentemente. Se hace especial hincapie en la calidad y validez de los estudios epidemiologicos y en la evaluacion y aplicacion de los resultados de los estudios de tests diagnosticos