José Wilson Noleto

A rare case of regression of brown tumors of tertiary hyperparathyroidism after parathyroidectomy and renal transplant: A 5-year follow-up.

Tertiary hyperparathyroidism (HPT) is a rare condition that affects patients with secondary HPT, which develop hyperplasia of the parathyroid glands, thus causing an increase in parathyroid hormone levels. Bone alterations are the main consequences of this condition including the development of osteolytic lesions called brown tumor. This article reports an unusual case of brown tumors located in the maxilla and mandible in a 19-year-old man with chronic renal failure with hyperplasia of the parathyroid glands. The lesions regressed approximately 5 months after the parathyroidectomy. At this same time, the patient underwent renal transplant. The patient was followed for 5 years, showing improvement in overall clinical status. There was also improvement of the results of laboratory tests and the pattern of trabecular bone. The correct diagnosis of oral lesions was of great relevance for the conservative treatment could have been chosen.

Cisto ósseo simples em pacientes sob tratamento ortodôntico: relato de dois casos

INTRODUCTION: simple bone cyst (traumatic bone cyst, hemorrhagic bone cyst, solitary bone cyst) is a non-neoplastic lesion which represents about 1% of all maxillary cysts, found mainly in mandibular body and symphysis. It is an intraosseous cavity covered by thin, loose fibrous connective tissue, without epithelial lining. Simple bone cysts are asymptomatic and are commonly found in routine radiographic examination as a well defined unilocular radiolucent lesion. Its etiopathogenesis remains obscure, but the local trauma is frequently related to its occurrence. OBJECTIVE: this article reports two cases of simple bone cyst found in routine radiographic examination of orthodontic treated patients. CASE REPORT AND DISCUSSION: in both cases, the clinical diagnosis was confirmed by biopsy and histological examination. The patients underwent surgical exploration and a radiographic follow up showed evidence of local healing. This study discuss if there is a relationship between the orthodontic trauma and the occurrence of simple bone cyst in these patients, or if it represents an incidental finding, since they are most frequently submitted to radiographic examination.