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Dive into the research topics where K.N. Yu is active.

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Featured researches published by K.N. Yu.


Journal of Environmental Radioactivity | 1992

The assessment of the natural radiation dose committed to the Hong Kong people

K.N. Yu; Z.J. Guan; M.J. Stokes; E.C.M. Young

Abstract The natural radionuclide ( 238 U, 226 Ra, 232 Th and 40 K) contents of soil samples at various locations in Hong Kong, building materials commonly used in Hong Kong and construction materials for roads have been determined by low background gamma-ray spectroscopy using an n-type high purity germanium detector. From the measured radionuclide contents, estimations have been made of the absorbed gamma dose rate in air and the indoor radon concentration in Hong Kong. Both are in good agreement with in-situ measurements. Finally, calculations have been made of the annual individual effective dose equivalent contributed by all kinds of natural background radiations. The total value is 3·2 mSv which is about 60% higher than the global average. Of this total value, 80% comes from the radiation from building materials. The present work suggests that building materials are the primary source of natural background radiation in Hong Kong. Therefore, more extensive studies and perhaps limitation of the radionuclide concentration of building materials in the near future seems necessary.


Applied Radiation and Isotopes | 2002

Determination of multi-element profiles of street dust using energy dispersive X-ray fluorescence (EDXRF)

Z.L.L. Yeung; Ron Chi-Wai Kwok; K.N. Yu

Street dust samples have been collected in different areas in Hong Kong associated with various levels of traffic and pedestrian flow, and the concentrations of 23 chemical elements have been determined using energy dispersive X-ray fluorescence (EDXRF). The 23 studied elements were Na, Al, Si, Cl, Ti, Ba, V, Cr, Mn, Fe, Co, K, Ca, Ni, Cu, Zn, As, Pb, Rb, Sr, Y, Zr and Sn. A profile for average street dust for Hong Kong has been determined by taking average values for different areas. The values for the Hong Kong street dust are commensurate with the values derived in previous investigations or for other countries, except that Hong Kong street dust has much higher Cl, Ca and As concentrations. A factor analysis gives four sources for the street dust in Hong Kong: namely, mixture of metallic dust and crustal material, vehicles, road pavement materials, and mixture of marine aerosols and crustal material.


Computer Physics Communications | 2006

Computer program TRACK_TEST for calculating parameters and plotting profiles for etch pits in nuclear track materials

D. Nikezic; K.N. Yu

Abstract A computer program called TRACK_TEST for calculating parameters (lengths of the major and minor axes) and plotting profiles in nuclear track materials resulted from light-ion irradiation and subsequent chemical etching is described. The programming steps are outlined, including calculations of alpha-particle ranges, determination of the distance along the particle trajectory penetrated by the chemical etchant, calculations of track coordinates, determination of the lengths of the major and minor axes and determination of the contour of the track opening. Descriptions of the program are given, including the built-in V functions for the two commonly employed nuclear track materials commercially known as LR 115 (cellulose nitrate) and CR-39 (poly allyl diglycol carbonate) irradiated by alpha particles. Program summary Title of the program: TRACK_TEST Catalogue identifier: ADWT Program obtainable from: CPC Program Library, Queens University of Belfast, N. Ireland Program summary URL: http://cpc.cs.qub.ac.uk/summaries/ADWT Computer: Pentium PC Operating systems: Windows 95+ Programming language: Fortran 90 Memory required to execute with typical data: 256 MB No. of lines in distributed program, including test data, etc.: 2739 No. of bytes in distributed program, including test data, etc.: 204 526 Distribution format: tar.gz External subprograms used: The entire code must be linked with the MSFLIB library Nature of problem: Fast heavy charged particles (like alpha particles and other light ions etc.) create latent tracks in some dielectric materials. After chemical etching in aqueous NaOH or KOH solutions, these tracks become visible under an optical microscope. The growth of a track is based on the simultaneous actions of the etchant on undamaged regions (with the bulk etch rate V b ) and along the particle track (with the track etch rate V t ). Growth of the track is described satisfactorily by these two parameters ( V b and V t ). Several models have been presented in the past describing the track development, one of which is the model of Nikezic and Yu (2003) [D. Nikezic, K.N. Yu, Three-dimensional analytical determination of the track parameters. Over-etched tracks, Radiat. Meas. 37 (2003) 39–45] used in the present program. The present computer program has been written to calculate coordinates of points on the track wall and to determine other relevant track parameters. Solution method: Coordinates of points on the track wall assuming normal incidence were calculated by using the method as described by Fromm et al. (1988) [M. Fromm, A. Chambaudet, F. Membrey, Data bank for alpha particle tracks in CR39 with energies ranging from 0.5 to 5 MeV recording for various incident angles, Nucl. Tracks Radiat. Meas. 15 (1988) 115–118]. The track is then rotated through the incident angle in order to obtain the coordinates of the oblique track [D. Nikezic, K.N. Yu, Three-dimensional analytical determination of the track parameters. Over-etched tracks, Radiat. Meas. 37 (2003) 39–45; D. Nikezic, Three dimensional analytical determination of the track parameters, Radiat. Meas. 32 (2000) 277–282]. In this way, the track profile in two dimensions (2D) was obtained. In the next step, points in the track wall profile are rotated around the particle trajectory. In this way, circles that outline the track in three dimensions (3D) are obtained. The intersection between the post-etching surface of the detector and the 3D track is the track opening (or the track contour). Coordinates of the track 2D and 3D profiles and the track opening are saved in separate output data files. Restrictions: The program cannot calculate track parameters for the incident angle of exactly 90°. The alpha-particle energy should be smaller than 10 MeV. Furthermore, the program cannot perform calculations for tracks in some extreme cases, such as for very low incident energies or very small incident angles. Additional comments: This is a freeware, but publications arising from using this program should cite the present paper and the paper describing the track growth model [D. Nikezic, K.N. Yu, Three-dimensional analytical determination of the track parameters. Over-etched tracks, Radiat. Meas. 37 (2003) 39–45]. Moreover, the references for the V functions used should also be cited. For the CR-39 detector: Function (1): S.A. Durrani, R.K. Bull, Solid State Nuclear Track Detection. Principles, Methods and Applications, Pergamon Press, 1987. Function (2): C. Brun, M. Fromm, M. Jouffroy, P. Meyer, J.E. Groetz, F. Abel, A. Chambaudet, B. Dorschel, D. Hermsdorf, R. Bretschneider, K. Kadner, H. Kuhne, Intercomparative study of the detection characteristics of the CR-39 SSNTD for light ions: Present status of the Besancon–Dresden approaches, Radiat. Meas. 31 (1999) 89–98. Function (3): K.N. Yu, F.M.F. Ng, D. Nikezic, Measuring depths of sub-micron tracks in a CR-39 detector from replicas using atomic force microscopy, Radiat. Meas. 40 (2005) 380–383. For the LR 115 detector: Function (1): S.A. Durrani, P.F. Green, The effect of etching conditions on the response of LR 115, Nucl. Tracks 8 (1984) 21–24. Function (2): C.W.Y. Yip, D. Nikezic, J.P.Y Ho, K.N. Yu, Chemical etching characteristics for cellulose nitrate, Mat. Chem. Phys. 95 (2005) 307–312. Running time: Order of several minutes, dependent on input parameters and the resolution requested by the user.


Radiation Measurements | 2003

Effects of stirring on the bulk etch rate of CR-39 detector

J.P.Y. Ho; C.W.Y. Yip; D. Nikezic; K.N. Yu

Abstract It is well established that the bulk etch rates for solid state nuclear track detectors are affected by the concentration and the temperature of the etchant. Recently, we found that the bulk etch rate for the LR 115 detector to be affected by stirring during etching. In the present work, the effects of stirring on the bulk etch rate of the CR-39 detector is investigated. One set of sample was etched under continuous stirring by a magnetic stirrer at 70°C in a 6.25 N NaOH solution, while the other set of samples was etched without the magnetic stirrer. After etching, the bulk etch thickness was measured using Form Talysurf PGI (Taylor Hobson, Leicester, England). It was found that magnetic stirring did not affect the bulk etch of the CR-39 detector, which was in contrast to the results for the LR 115 detector.


Mutation Research | 2009

Up-regulation of ROS by mitochondria-dependent bystander signaling contributes to genotoxicity of bystander effects

Shaopeng Chen; Ye Zhao; Guoping Zhao; Wei Han; Lingzhi Bao; K.N. Yu; Lijun Wu

Genomic instability can be observed in bystander cells. However, the underlying mechanism(s) is still relatively unclear. In a previous study, we found that irradiated cells released mitochondria-dependent intracellular factor(s) which could lead to bystander gamma-H2AX induction. In this paper, we used normal (rho(+)) and mtDNA-depleted (rho(0)) human-hamster hybrid cells to investigate mitochondrial effects on the genotoxicity in bystander effect through medium transfer experiments. Through the detection of DNA double-strand breaks with gamma-H2AX, we found that the fraction of gamma-H2AX positive cells changed with time when irradiation conditioned cell medium (ICCM) were harvested. ICCM harvested from irradiated rho(+) cells at 10 min post-irradiation (rho(+) ICCM(10 min)) caused larger increases of bystander gamma-H2AX induction comparing to rho(0) ICCM(10 min), which only caused a slight increase of bystander gamma-H2AX induction. The rho(+) ICCM(10 min) could also result in the up-regulation of ROS production (increased by 35% at 10 min), while there was no significant increase in cells treated with rho(0) ICCM(10 min). We treated cells with dimethyl sulfoxide (DMSO), the scavenger of ROS, and quenched gamma-H2AX induction by rho(+) ICCM. Furthermore, after the medium had been transferred and the cells were continuously cultured for 7 days, we found significantly increased CD59(-) gene loci mutation (increased by 45.9%) and delayed cell death in the progeny of rho(+) ICCM-treated bystander cells. In conclusion, the work presented here suggested that up-regulation of the mitochondria-dependent ROS might be very important in mediating genotoxicity of bystander effects.


Radiation Measurements | 2003

Three-dimensional analytical determination of the track parameters: over-etched tracks

D. Nikezic; K.N. Yu

Three-dimensional analytical determinations of track parameters are extended to cases where the tracks are in the rounded and spherical phases of development. The equation for the track wall in three dimensions and the equation of contour line of the opening were derived for all types of tracks. The expression for the surface area of the track opening has also been found. The equations come up to the well-known expressions for minor and major axes for the special case of constant track etch rate.


Environmental Modelling and Software | 2005

Study of pollution dispersion in urban areas using Computational Fluid Dynamics (CFD) and Geographic Information System (GIS)

A.K.M. Chu; Ron Chi-Wai Kwok; K.N. Yu

Abstract The computational fluid dynamics software, CFX5.5 is employed to determine dispersions of emissions from vehicles traversing the streets. Information on the layouts and heights of buildings in the selected area is contained in a digitized map layer of buildings. The Geographic Information System software, ArcView 3.2a, with its programming facility, Avenue, has been used to extract the coordinates and heights of each building polygon under research. These are then input into the CFX-Build component of CFX5.5 to construct the geometry for simulations. The dispersion characteristics, such as the spread of the pollution dispersions, have been determined for different wind speeds and wind directions.


Health Physics | 1997

A survey of radon and thoron progeny for dwellings in Hong Kong

K.N. Yu; E. C. M. Young; M. J. Stokes; Z. J. Guan; K. W. Cho

The potential alpha energy concentrations of radon and thoron progeny have been surveyed for dwellings in Hong Kong and the mean values are obtained as 3.58 and 2.29 mWL, respectively. The relative importance of the value for thoron is unexpectedly high, which is attributed to the high 232Th content of the building materials used in Hong Kong. It has also been found that the potential alpha energy concentration values for radon progeny changed dramatically with the season due to the different aerosol contents in the air in different seasons. The factors affecting the potential alpha energy concentration values have also been studied. These factors fall into three categories, namely (1) the building characteristics including age of the buildings, wall coverings and floor coverings; (2) the location of sites including nearby environments and the elevation of the sites; and (3) the meteorological parameters including wind speed, atmospheric pressure, air temperature and relative humidity. For categories (1) and (2), all factors seem to affect the potential alpha energy concentration values, although the effects may be different for radon and thoron progeny, which may be due to the very much different half lives of radon and thoron gas and to the different behavior of radon and thoron progeny in the attachment to aerosols. For category (3), only wind speed has been found to have effects.


Mutation Research | 2010

Nitric oxide mediated DNA double strand breaks induced in proliferating bystander cells after alpha-particle irradiation

Wei Han; Shaopeng Chen; K.N. Yu; Lijun Wu

Low-dose alpha-particle exposures comprise 55% of the environmental dose to the human population and have been shown to induce bystander responses. Previous studies showed that bystander effect could induce stimulated cell growth or genotoxicity, such as excessive DNA double strand breaks (DSBs), micronuclei (MN), mutation and decreased cell viability, in the bystander cell population. In the present study, the stimulated cell growth, detected with flow cytometry (FCM), and the increased MN and DSB, detected with p53 binding protein 1 (53BP1) immunofluorescence, were observed simultaneously in the bystander cell population, which were co-cultured with cells irradiated by low-dose alpha-particles (1-10 cGy) in a mixed system. Further studies indicated that nitric oxide (NO) and transforming growth factor beta1 (TGF-beta1) played very important roles in mediating cell proliferation and inducing MN and DSB in the bystander population through treatments with NO scavenger and TGF-beta1 antibody. Low-concentrations of NO, generated by spermidine, were proved to induce cell proliferation, DSB and MN simultaneously. The proliferation or shortened cell cycle in bystander cells gave them insufficient time to repair DSBs. The increased cell division might increase the probability of carcinogenesis in bystander cells since cell proliferation increased the probability of mutation from the mis-repaired or un-repaired DSBs.


Physics in Medicine and Biology | 1999

Monte Carlo calculated output factors of a Leksell Gamma Knife unit

Joel Y. C. Cheung; K.N. Yu; Robert T K Ho; C. P. Yu

The Leksell Gamma Knife is a standard radiosurgical tool for treating brain lesions by directing beams of gamma radiation to a specific region. The diameter of the gamma beams is confined by collimator systems and available collimator sizes are 4, 8, 14 and 18 mm. The reduction in dose rate for each collimator helmet is called the output factor (OPF). Experimental determination of OPFs is difficult due to the extremely narrow beams for which the dose is determined. In the present work, the PRESTA version of the EGS4 Monte Carlo code was used to obtain relative OPFs for the Leksell Gamma Knife for collimator sizes of 14, 8 and 4 mm (relative to that of the 18 mm collimator). A spherical probe with a radius of 1 mm was utilized in this computer experiment. Our Monte Carlo results gave OPFs of 0.974, 0.951 and 0.872 for the 14 mm, 8 mm and 4 mm collimators respectively, relative to the 18 mm collimator. Our calculated OPF for the 4 mm collimator helmet was more than 8% higher than the value currently used, but in good agreement with the average of experimental values obtained by various Gamma Knife centres throughout the world and with the value now recommended by the manufacturer, Elekta (Elekta Instrument AB, Skeppargatan 8, S-114 52 Stockholm, Sweden).

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D. Nikezic

University of Kragujevac

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Shuk Han Cheng

City University of Hong Kong

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C.W.Y. Yip

City University of Hong Kong

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V. W. Y. Choi

City University of Hong Kong

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J.P.Y. Ho

City University of Hong Kong

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F.M.F. Ng

City University of Hong Kong

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Wei Han

Hefei Institutes of Physical Science

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C. Y. P. Ng

City University of Hong Kong

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Tsang Cheung

City University of Hong Kong

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B.M.F. Lau

City University of Hong Kong

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