Kenji Nakaya
Otsuka Pharmaceutical
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Publication
Featured researches published by Kenji Nakaya.
Bioorganic & Medicinal Chemistry | 1999
Kazumi Kondo; Hidenori Ogawa; Hiroshi Yamashita; Hisashi Miyamoto; Michinori Tanaka; Kenji Nakaya; Kazuyoshi Kitano; Yoshitaka Yamamura; Shigeki Nakamura; Toshiyuki Onogawa; Toyoki Mori; Michiaki Tominaga
We previously reported a series of benzazepine derivatives as orally active nonpeptide arginine vasopressin (AVP) V2 receptor antagonists. After the lead structure OPC-31260 was structurally evaluated and optimized, the introduction of the 7-Cl moiety on the benzazepine and 2-CH3 on the aminobenzoyl moiety enhanced its oral activity. The new AVP-V2 selective antagonist OPC-41061 was determined to be a potent and orally active agent.
Journal of Medicinal Chemistry | 1996
Hidenori Ogawa; Hiroshi Yamashita; Kazumi Kondo; Yoshitaka Yamamura; Hisashi Miyamoto; Keizo Kan; Kazuyoshi Kitano; Michinori Tanaka; Kenji Nakaya; Shigeki Nakamura; Toyoki Mori; Michiaki Tominaga; Youichi Yabuuchi
Archive | 1992
Hidenori Ogawa; Kazumi Kondo; Hiroshi Yamashita; Kenji Nakaya; Hajime Komatsu; Michinori Tanaka; Kazuyoshi Kitano; Michiaki Tominaga; Yoichi Yabuuchi
Journal of Medicinal Chemistry | 1993
Hidenori Ogawa; Yoshitaka Yamamura; Hisashi Miyamoto; Kazumi Kondo; Hiroshi Yamashita; Kenji Nakaya; Tomihiko Chihara; Toyoki Mori; Michiaki Tominaga; Youichi Yabuuchi
Archive | 1993
Hidenori Axa Nakase Nishinokoshi Ogawa; Kazumi Aza Inamoto Kondo; Hiroshi Yamashita; Kenji Nakaya; Hajime Komatsu; Michinori Tanaka; Kazuyoshi Nishiyamada Hinoki Kitano; Michiaki Tominaga; Yoichi Yabuuchi
Archive | 1991
Hajime Komatsu; Kazumi Kondo; Hisashi Miyamoto; Kenji Nakaya; Hidenori Ogawa; Shinya Takara; Michinori Tanaka; Michiaki Tominaga; Yoichi Yabuuchi; Hiroshi Yamashita
Archive | 1997
Toyoki Mori; Michiaki Tominaga; Fujio Tabusa; Kazuyoshi Nagami; Kaoru Abe; Kenji Nakaya; Isao Takemura; Tomoichi Shinohara; Yoshihisa Tanada; Takahito Yamauchi
Archive | 1993
Hidenori Ogawa; Kazumi Kondo; Hiroshi Yamashita; Kenji Nakaya; Hajime Komatsu; Michinori Tanaka; Kazuyoshi Kitano; Michiaki Tominaga; Yoichi Yabuuchi
Archive | 1991
Takafumi Fujioka; Kazuyoshi Kitano; Hajime Komatsu; Kazumi Kondo; Hisashi Miyamoto; Kenji Nakaya; Hidenori Ogawa; Michinori Tanaka; Shuji Teramoto; Michiaki Tominaga; Yoichi Yabuuchi; Hiroshi Yamashita; 賢治 中矢; 和良 北野; 寿 宮本; 道明 富永; 修二 寺本; 英則 小川; 一 小松; 博司 山下; 理紀 田中; 洋一 薮内; 孝文 藤岡; 一見 近藤
Archive | 1997
Toyoki Mori; Michiaki Tominaga; Fujio Tabusa; Kazuyoshi Nagami; Kaoru Abe; Kenji Nakaya; Isao Takemura; Tomoichi Shinohara; Yoshihisa Tanada; Takahito Yamauchi
