Khalid El Khader

Lymphoepithelioma-like carcinoma of the bladder: a case report

IntroductionLymphoepitheliomas are malignant epithelial tumors of the nasopharynx characterized by an important lymphoid proliferation at histological examination. Lymphoepithelioma-like carcinoma is a rare tumor of the bladder for which the therapeutic strategy is not clearly defined.Case presentationWe report the case of a 64-year-old Moroccan man who presented with macroscopic hematuria. Investigations revealed a muscle-invasive lymphoepithelioma-like carcinoma of the bladder. Therefore he underwent a radical cystoprostatectomy with a good outcome.ConclusionThis case illustrates pathogenic, clinical and therapeutic features of this unusual tumor.

Urethral hemangioma: case report and review of the literature.

Hemangiomas are benign vascular tumors. They are the prerogative of the liver and skin. And genitourinary localizations are rare and have only been rarely reported in the prostat, bladder, ureter or the perineum. In the light of published cases, urethral hemangiomas are mostly found in males. Few cases of hemangioma in the female urethra were reported. We report a cavernous hemangioma of the urethra in a 61 years old patient who presented bleeding from the urethra and micturition disorders. Physical examination revealed a tumor 3 cm x 2 polyploid arising from the terminal urethra (urethral hemangioma). We performed surgical resection of the tumor, along with bladder drainage. The postoperative course was simple. We update through a review of the literature aspects of the diagnostic and therapeutic care of the urethral hemangioma.

Traitement endoscopique du reflux vésico-urétéral par injection sous-méatique de graisse autologue. A propos de deux cas

The authors report two cases of endoscopic treatment of vesico-ureteral reflux by submeatic injection of autologous fat. We describe the technique of prelevement and injection. The immediate results confirm the efficacity of this procedure. The long-term follow-up will allow us to adopt it and to give it some modifications.

Prostatic Abscess on Xanthogranulomatous Prostatitis: Uncommon Complication of an Uncommon Disease

Xanthogranulomatous prostatitis is a rare benign inflammatory process of the prostate. Only few cases have been reported in the English literature. Xanthogranulomatous prostatitis is usually an incidental finding after needle biopsy or transurethral resection of the prostate in patients suffering from low urinary tract symptoms. We report the case of a 59-years-old patient diagnosed with prostatic abscess managed by transurethral resection of the prostate. Histopathological examination of resected prostatic tissue revealed abscessed xanthogranulomatous prostatitis with no evidence of malignancy. Xanthogranulomatous prostatitis presenting as a prostatic abscess is a rare finding. To the best of our knowledge our case represents the fourth case of xanthogranulomatous prostatitis presenting as prostatic abscess reported in the English literature so far.

Lymphoepithelioma-Like Carcinoma of the Bladder: A Case Report of a Rare and Particular Variant of Urothelial Carcinoma

Lymphoepithelioma-like carcinoma of the bladder (LELCB) is a rare variant of urothelial carcinoma first described by Zukerberg in 1991 and confirmed as a variant of urothelial carcinoma by the WHO classification of tumors of the urinary system. LELCB is characterized by a marked infiltration of lymphocytes in the area involved by the tumor which may coexist with the conventional urothelial carcinoma. LELCB are classified according to the percentage of lymphoepithelioma component within the tumor with the prognosis depending on the percentage. We report a new case of pure LELCB occurring in 63-year-old woman presenting with hematuria. Ultrasonography and cystoscopy revealed a large tumor on the left lateral wall of the bladder. Transurethral resection of the bladder tumor (TURBT) was performed. Pathological and immunohistochemical analysis revealed a high-grade muscle-invasive LELCB (G3pT2). The patient underwent an adjuvant systemic chemotherapy with no recurrence after a ten-month follow-up. To our knowledge, this is the second Moroccan case of LELCB reported in the English literature. Although its rare occurrence prognosis and ideal therapeutic management of LELCB have not been clearly established yet, literature findings encourage the adoption of a conservative approach in treatment of LELCB.

Kyste de la vésicule séminale: à propos d’un cas

We report the case of a patient with symptomatic seminal vesicle cyst on the right side. Imaging examinations (pelvic and endorectal ultrasound, abdominal-pelvic tomodensitometry and MRI) were perdormed and the patient underwent surgical removal of the cyst. In light of this case study, epidemiology, diagnosis and treatment options are discussed.

Fistule vésico-vaginale néoplasique secondaire à une tumeur de vessie: une entité rare

Vesico-vaginal Fistula (VVF) secondary to bladder cancer is extremely rare. We report the case of a 54-year old post-menopausal patient with neoplasic Vesico-vaginal Fistula (VVF), without any surgical antecedents or recent obstetric trauma. Biopsy of the edges of the fistula confirmed urothelial carcinoma. In light of this observation, we here discuss VVF etiological forms and their different therapeutic strategies.

Mésothéliome paratesticulaire malin : cas clinique et revue de la littérature

Les mesotheliomes sont des tumeurs rares, liees surtout a l’exposition a l’amiante. La localisation dans la tunique vaginale est moins frequente que les localisations pleurale et peritoneale. Nous faisons etat du cas clinique d’un jeune patient de 30 ans qui presentait une masse testiculaire gauche avec lesion tissulaire intratesticulaire visible a l’echographie. Il a subi une orchidectomie ; l’examen anatomopathologique de la piece operatoire orientait le diagnostic en faveur d’un mesotheliome malin de la tunique vaginale. Une hemiscrotectomie a ete realisee par la suite, et le bilan d’extension n’a pas revele de lesion secondaire. L’evolution s’est averee favorable moyennant un recul de quatre ans. A travers ce cas clinique et par l’entremise d’une revue de litterature, nous analysons les aspects epidemiologiques, diagnostiques et therapeutiques de cette pathologie rare.

Complications de l’hormonothérapie anti-androgénique du cancer de la prostate

Les effets indesirables de l’hormonotherapie anti-androgenique (HAA) dans le traitement du cancer de la prostate sont attribuables a la carence d’androgenes. L’HAA entraine le syndrome de castration, qui se caracterise par une diminution de la libido, la dysfonction erectile, l’asthenie, des bouffees de chaleur, la diminution des capacites intellectuelles et la depression. Il en resulte egalement une augmentation de la graisse abdominale, ce qui favorise l’insulinoresistance et le diabete. La perte de la densite minerale osseuse secondaire a l’HAA entraine un risque fracturaire accru. Il existe de plus un risque cardiovasculaire important du aux facteurs metaboliques. L’effet therapeutique de l’HAA doit donc etre soupese en regard de la toxicite liee a l’hypogonadisme.

Névralgies pudendales : À propos de trois cas

Les nevralgies pudendales, ou syndrome du canal d’Alcock, sont des douleurs perineales declenchees par la position assise et dont le diagnostic est clinique. La positivite des blocs anesthesiques confirme ce diagnostic. Cependant, les conduites therapeutiques restent parfois subjectives. Par l’analyse de trois cas cliniques de patients suivis en consultation d’algologie, nous essayons de distinguer entre les patients qui necessitent un traitement chirurgical d’emblee, et ceux qui peuvent etre mis sous traitement medicamenteux exclusif. Nous decouvrons egalement la valeur du facteur temps dans la prise en charge de cette maladie invalidante.