Ljiljana Bogunovic
Washington University in St. Louis
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Clinical Orthopaedics and Related Research | 2013
Ljiljana Bogunovic; Meghan Gottlieb; Gail Pashos; Geneva Baca; John C. Clohisy
BackgroundDespite the successes of hip arthroscopy, clinical failures do occur, and identifying risk factors for failure may facilitate refinement of surgical indications and treatment. Knowledge regarding the reasons for treatment failures may also improve surgical decision making.Questions/purposesWe (1) characterized patients whose symptoms recurred after hip arthroscopy necessitating a revision hip preservation procedure or hip arthroplasty, (2) determined the etiologies of failure, (3) and reported the profile of revision surgical procedures.MethodsIn a prospective database of 1724 consecutive hip surgeries, we identified 58 patients (60 hips) with a history of failed hip arthroscopy. Thirty-seven patients (38 hips) underwent revision hip preservation and 21 (22) hip arthroplasty. Thirty-nine (67%) were female. Demographics, etiology of failure, and type of revision surgery were analyzed.ResultsPatients treated with revision hip preservation were younger, had a lower BMI, and lower Tönnis osteoarthritis grade at the time of revision surgery compared to patients treated with hip arthroplasty. Common etiologies of failure were residual femoroacetabular impingement (68%) and acetabular dysplasia (24%) in patients treated with revision hip preservation and advanced osteoarthritis in patients treated with hip arthroplasty. The revision preservation procedures included arthroscopy in 16 (42%), arthroscopy with limited open capsulorraphy in two (5.3%), periacetabular osteotomy in nine (24%), and surgical dislocation in 12 (32%).ConclusionsResidual or unaddressed structural deformity of the hip and underlying osteoarthritis are commonly associated with failure after hip arthroscopy. Thorough patient evaluation with detailed characterization of structural hip anatomy and articular cartilage integrity are critical to the selection of proper surgical intervention and successful patient outcome.Level of EvidenceLevel IV, prognostic study. See Instructions for Authors for a complete description of levels of evidence.
Journal of Bone and Joint Surgery, American Volume | 2008
Padhraig F. O'Loughlin; Simon Morr; Ljiljana Bogunovic; Abraham D. Kim; Brian Park; Joseph M. Lane
Animal fracture models have been extensively applied to preclinical research as a platform to identify and characterize normal and abnormal physiological processes and to develop specific maneuvers that alter the biology and biomechanics being examined. The choice of animal model employed in a study bears a direct relationship to the specific intervention being analyzed. The animal models employed should be described clearly, control-group data should be established, and reproducibility should be defined from experiment to experiment and from institution to institution so that quantitative and qualitative outcomes can be reliably compared and contrasted to other related studies.
Current Opinion in Pediatrics | 2009
Ljiljana Bogunovic; Shevaun M. Doyle; Maria G Vogiatzi
Purpose of review The purpose of this review is to provide a comprehensive synopsis of pediatric bone density. Osteoporosis of the adult is a well established clinical problem, and algorithms to diagnose and treat this disease are recognized throughout the medical community. Osteoporosis or ‘low bone mass’ in pediatrics, on the other hand, is a rather new and evolving area, with certain unique diagnostic and clinical challenges. Recent findings Recent findings in the literature include benefits and limitations of pediatric bone densitometry techniques, proper interpretation of the results of these various techniques, efforts to establish standards and guidelines for diagnosing low bone mass in children and adolescents, optimization of bone growth and mineral accrual for life, pediatric bone mineral density and fracture risk prediction, as well as a clearer awareness of bone fragility in children. Summary Throughout the last decade, great strides have been made in our understanding of pediatric metabolic bone disease. These will be the focus of this review.
Journal of Bone and Joint Surgery, American Volume | 2014
Ljiljana Bogunovic; Lisa M. Kruse; Amanda K. Haas; Laura J. Huston; Rick W. Wright
Background:Meniscal repair and preservation are the goal, when possible, of the treatment of meniscal injury. Current research on second-generation all-inside repair systems has been limited to a maximum of three years of follow-up. The purpose of this study was to evaluate the mid-term clinical suc
Orthopedic Clinics of North America | 2013
Ljiljana Bogunovic; Steven M. Cherney; Marcus Rothermich; Michael J. Gardner
The incidence of osteoporotic fractures has been steadily rising along with the aging of the population. Surgical management of these fractures can be a challenge to orthopedic surgeons. Diminished bone mass and frequent comminution make fixation difficult. Advancements in implant design and fixation techniques have served to address these challenges and when properly applied, can improve overall outcome. The purpose of this review is to describe fixation challenges of common osteoporotic fractures and provide options for successful treatment.
Journal of Knee Surgery | 2014
Ljiljana Bogunovic; Majd Tarabichi; David A. Harris; Rick W. Wright
Fractures of the tibial eminence are rare, accounting for less than 1% of the injuries involving the anterior cruciate ligament (ACL). Most agree that nondisplaced fractures can be managed nonoperatively, but debate exists over the ideal treatment of displaced fractures. This systematic review evaluates the outcome of nonoperatively and operatively managed displaced tibial eminence fractures. The PubMed, Embase, and Cochrane databases were queried. Inclusion criteria included reported outcomes of displaced tibial eminence fractures, minimum 2-year follow-up, and English language. Outcomes reported were pooled and included the following: clinical instability (Lachman/anterior drawer, pivot shift, and KT 1000), patient-reported pain and/or instability, return to sport, Lysholm, Tegner, and the need for ACL reconstruction. Comparison was made in the outcomes of nonoperatively and operatively treated fractures and between suture and screw fixation techniques. Overall 16 studies met the inclusion criteria. The pooled mean age was 23 years and mean follow-up was 35 months. Clinical instability was seen in 70% of nonoperatively treated patients and 14% of operatively treated patients (p < 0.0001). Patient-reported instability was higher in nonoperatively treated patients (54 vs. 1.2%, p < 0.0001), as was the rate of ACL reconstruction (10 vs. 1.0%, p = 0.036). In comparing suture fixation to screw fixation, patient-reported instability and the rate of ACL reconstruction were equivalent. Patients treated with screw fixation had a higher incidence of clinically measured instability (Lachman and KT arthrometer) and an increased rate of hardware removal (3.9 vs. 64.9%, p < 0.05). Surgically managed patients report less instability, are higher functioning, and require fewer ACL reconstructions when compared with nonoperatively treated patients. Suture fixation was associated with improvements in clinical measures of stability and decreased need for hardware removal; however, patient perception of stability and need for ACL reconstruction was no different between the two treatment methods.
American Journal of Sports Medicine | 2014
Ljiljana Bogunovic; Devyani Hunt; Heidi Prather; Perry L. Schoenecker; John C. Clohisy
Background: Periacetabular osteotomy is a well-described surgical intervention for symptomatic acetabular deformities in skeletally mature patients. Data regarding return to athletic activity or sport after this procedure are still limited. Purpose: To evaluate the ability of patients to return to preoperative levels of activity after periacetabular osteotomy. Study Design: Case series; Level of evidence, 4. Methods: This is a retrospective review of active patients treated with periacetabular osteotomy for acetabular deformity correction. Patients were identified as those with preoperative University of California–Los Angeles activity levels ≥7. Patient demographics, operative data, radiographic measures, and clinical outcomes were documented prospectively. The University of California–Los Angeles activity score, Harris Hip Score, Hip Dysfunction and Osteoarthritis Outcome Score, and Western Ontario and McMaster Universities Osteoarthritis Index were used to measure clinical outcomes, and details regarding activity and satisfaction were analyzed. Results: This study included 36 patients (39 hips; 15 males and 21 females) whose average age was 25 years (range, 15-45 years) and whose average body mass index was 24 ± 3.5 kg/m2. Mean follow-up was 33 months (range, 18-59 months). Preoperatively, the average lateral center edge angle, anterior center edge angle, and acetabular index were 10°, 14°, and 21°, respectively; 92% of patients had a Tönnis osteoarthritis grade of 0 or 1. One patient failed hip preservation surgery and went on to total hip arthroplasty 27 months after periacetabular osteotomy. Of the remaining patients, 71% reported an increase or no change in activity level postoperatively. The University of California–Los Angeles score was also unchanged (9.2 vs 8.8, P = .157), and the Harris Hip Score (63 vs 87, P < .001), Hip Dysfunction and Osteoarthritis Outcome Score–Quality of Life (38 vs 71, P < .001), and Western Ontario and McMaster Universities Osteoarthritis Index (71 vs 92, P < .001) results improved from preoperative levels. There was a 97% rate of satisfaction with the surgery. Four patients (11%) reported hip pain as the primary factor limiting postoperative activity. Conclusion: The majority (71%) of active patients with hip dysplasia return to presurgical or higher activity levels after open hip preservation surgery with the periacetabular osteotomy.
Journal of Hand Surgery (European Volume) | 2012
Ljiljana Bogunovic; Richard H. Gelberman; Charles A. Goldfarb; Martin I. Boyer; Ryan P. Calfee
PURPOSE To quantify the impact of maintaining antiplatelet medication during hand and wrist surgery on bleeding and functional outcomes. METHODS This prospective cohort trial compared operative outcomes and complications of hand and wrist surgery in patients without interruption of daily antiplatelet medications (n = 107 procedures) with control patients (n = 107 procedures). We determined rates of complications requiring reoperation for each group. We compared measures of surgical site bleeding (extent of ecchymosis or hematoma formation), patient-rated outcome assessment (Quick Disabilities of the Arm, Shoulder, and Hand score and visual analog scales of pain and swelling), and 2-point discrimination between groups. Data were collected preoperatively and postoperatively at 2 and 4 weeks. We confirmed control and antiplatelet populations to be similar for data analysis according to health status (Short Form-12) and percentage of bony procedures. RESULTS One patient receiving antiplatelet medication required reoperation for surgical site bleeding after wrist arthrodesis (0.9%). There were no complications in the control group. The extent of postoperative ecchymosis was similar in the antiplatelet and control patients at 2 weeks (16 vs 19 mm) and 4 weeks (1 vs 1 mm). Hematoma rates were not increased for patients receiving antiplatelet medication (17% vs 14% at 2 wk). Patient-rated function scores were equivalent at baseline and at follow-up between groups. A total of 22 control patients and 20 patients receiving antiplatelet medication had transiently increased 2-point discrimination (≥ 2-mm change) postoperatively. CONCLUSIONS Bleeding-related perioperative complications were rare when continuing antiplatelet medications without interruption for hand and wrist surgery. Maintenance of antiplatelet medication does not appear to negatively affect patient-rated or objective measures of function, although surgical-site bleeding may be greatest in patients taking higher-dose antiplatelet medication and undergoing bony procedures. TYPE OF STUDY/LEVEL OF EVIDENCE Therapeutic II.
Clinics in Sports Medicine | 2014
Justin S. Yang; Ljiljana Bogunovic; Rick W. Wright
Osteochondritis dissecans is a potentially devastating cause of knee pain in adolescents and adults. Prognosis and treatment depends on the stability of the lesion and the age of the patient. Skeletally immature patients with stable lesions are amenable for nonoperative treatment. Nonoperative treatment is less predictable in skeletally mature patients and patients with unstable lesions. Lesion size, location, stability along with symptomatology should all be considered before initiating treatment. Modalities of nonoperative treatment can range from activity modification to complete immobilization. Close follow-up is recommended to monitor healing progression and symptom resolution.
Arthroscopy | 2018
David L. Bernholt; Rick W. Wright; Matthew J. Matava; Robert H. Brophy; Ljiljana Bogunovic; Matthew Smith
Purpose: The purpose of this study was to test the hypothesis that Patient Reported Outcomes Measurement Information System (PROMIS) computer-adaptive testing (CAT) physical function and pain interference scores can detect early variations in postoperative outcomes following arthroscopic partial meniscectomy and to determine whether age, sex, body mass index, mechanical symptoms, duration of symptoms, and the severity of chondrosis affect these scores. Methods: Seventyfive patients who had undergone a partial meniscectomy between September 2015 and March 2016 and had both preoperative and postoperative PROMIS-CAT data for physical function, pain interference, and depression were included. Demographic, clinical, and surgical data including the presence of intraoperative chondral lesions were collected for statistical analysis to assess for factors that led to differences in PROMIS-CAT outcomes. Results: Preoperatively, patients had decreased physical function and increased pain interference in excess of 1 standard deviation from the general population with mean PROMIS scores of 38.5 and 63.5, respectively. At the 6-week postoperative visit, patients had significant improvements in both physical function and pain interference with mean scores of 43.4 (P < .001, SE 1⁄4 0.75) and 55.5 (P < .001, SE 1⁄4 0.83). Female patients had less improvement in PROMIS physical function (P 1⁄4 .03) and depression (P 1⁄4 .02) scores postoperatively compared with male patients. Patients with high-grade articular cartilage lesions had less improvement in physical function (P 1⁄4 .014) and pain interference (P 1⁄4 .010) at 6 weeks postoperative compared with patients with low grade or no chondral lesion. Conclusions: PROMIS-CAT provides responsive outcome measures to early postoperative changes in physical function and pain following arthroscopic partial meniscectomy and has prognostic value in patient outcomes 6 weeks after procedure. Level of Evidence: Level IV case series.