Maheshwari P. Khare

Two pregnane ester glycosides from Pergularia pallida

Abstract Two new pregnane ester glycosides designated as pallidine and pallidinine have been isolated from the dried twigs of Pergularia pallida . Chemical and spectroscopic evidences are consistent with the structure 12,20-di- O -benzoyl sarcostin-3- O -β- d -oleandroside and 12,20-di- O -benzoyl-sarcostin-3- O -β- d -cymaropyranosyl(1 → 4)-β- d -oleandropyranoside for pallidine and pallidinine respectively.

Cissogenin, a pregnane genin from Marsdenia tenacissima

Abstract A new polyhydroxy pregnane designated as cissogenin has been isolated from the seeds of Marsdenia tenacissima . Its structure has been established as 3β,11α,12β,14β,20 S -pentahydroxy-pregn-5-ene.

A pregnane glycoside from Streblus asper

Abstract A pregnane glycoside, named sioraside, has been isolated from Streblus asper. Its chemical and spectroscopic data are consistent with the structure 3β, 14β-dihydroxypregn-20-one-3-O-β- d -(3-O-methyl)-glueopyranoside.

Structure of sarcobiose

Abstract A new, nonreducing disaccharide, sarcobiose, has been isolated from the dried twigs of Sarcostemma brevistigma . On the basis of chemical and spectroscopic evidence and identification of its hydrolysis product, its structure has been established as 3,4-anhydro-2,6-dideoxy-β- d - lyxo -hexopyranosyl 6-deoxy-3- O -methyl-β- d -allopyranoside.

A pregnane ester diglycoside from Hemidesmus indicus

Abstract A new pregnane ester diglycoside named desinine has been isolated from the dried twigs of Hemidesmus indicus . On the basis of chemical and spectroscopic evidence, its structure has been established as drevogenin B-3- O -β- D -oleandropyranosyl-(1→4)-β- D -oleandropyranoside.

A cardenolide tetraglycoside from Oxystelma esculentum

A new cardenolide tetraglycoside, oxyline, was isolated from the dried roots of Oxystelma esculentum. On the basis of chemical and spectroscopic evidence the structure of oxyline was established as 3-epi-uzarigenin-3-O-beta-D-cymaropyranosyl-(1----4)-O-beta- D-thevetopyranosyl-(1----4)-O-beta-D-cymaropyranosyl- (1----4)-O-beta-D-digitoxopyranoside.

Tenasogenin, a pregnane ester from Marsdenia tenacissima

Abstract A new polyhydroxy pregnane ester named tenasogenin was isolated from the seeds of Marsdenia tenacissima. On the basis of chemical and spectroscopic evidence and identification of its hydrolysis products, its structure has been established as 11α-O-β,β-dimethylacryloyl-3β,12β,14β,20R-tetrahydroxypregn-5-ene.

Structure of Vimose

Abstract The structure of vimose, a novel tetrasaccharide isolated from the dried twigs of Orthenthera viminea (Family: Asclepiadaceae) has been established as O-β-L-diginopyranosyl-(1 →4)-O-β-L-diginopyranosyl-(1 →4)-O-β-L-diginopyranosyl-(1 → 4)-α-L-diginopyranose 1 on the basis of spectral and chemical evidence.

Structure of brevobiose

Abstract A new disaccharide, brevobiose ( 1 ), has been isolated from the dried twigs of Sarcostemma brevistigma . The structure of 1 has been established as 4- O -(6-deoxy-2- O -methyl-β- d -allopyranosyl)- d -boivinose on the basis of chemical and spectroscopic evidence, and identification of its hydrolysis products.

Cardenolide diglycosides from Oxystelma esculentum

Abstract Two new cardenolide diglycosides, named oxystelmoside and oxystelmine, were isolated from the dried roots of Oxystelma esculentum . On the basis of