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Dive into the research topics where Marco Santagostino is active.

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Featured researches published by Marco Santagostino.


Tetrahedron Letters | 1994

A mild oxidizing reagent for alcohols and 1,2-diols: o-iodoxybenzoic acid (IBX) in DMSO

Marco Frigerio; Marco Santagostino

Abstract o-Iodoxybenzoic acid (IBX) smoothly oxidizes primary and secondary alcohols to aldehydes and ketones, respectively. 1,2-Diols are converted to α-ketols or α-diketones without any oxidative cleavage of the glycol CC bond. IBX oxidations are easily conducted in DMSO solution at room temperature, with yields ranging from good to quantitative.


Tetrahedron Letters | 1998

A GENERAL, 1+4 APPROACH TO THE SYNTHESIS OF 3(5)-SUBSTITUTED PYRAZOLES FROM ALDEHYDES

Nicoletta Almirante; Alberto Cerri; Giorgio Fedrizzi; Giuseppe Marazzi; Marco Santagostino

Abstract A new, one-pot preparation of 3(5)-substituted-1H-pyrazole is described that employs Horner-Emmons reaction of aldehydes with dianion of novel phosphonate 1 and proceeds through cyclization of N-sodium salt of α,β-unsaturated tosylhydrazones 2 .


Journal of Organic Chemistry | 1995

Oxidation of Alcohols with o-Iodoxybenzoic Acid in DMSO: A New Insight into an Old Hypervalent Iodine Reagent

Marco Frigerio; Marco Santagostino; Simona Sputore; Giovanni Palmisano


Journal of Organic Chemistry | 1996

Hypervalent Iodine Oxidants: Structure and Kinetics of the Reactive Intermediates in the Oxidation of Alcohols and 1,2-Diols by o-Iodoxybenzoic Acid (IBX) and Dess−Martin Periodinane. A Comparative 1H-NMR Study

Sergio De Munari; and Marco Frigerio; Marco Santagostino


Journal of Medicinal Chemistry | 2001

17α-O-(Aminoalkyl)oxime derivatives of 3β, 14β-dihydroxy-5β-androstane and 3β-hydroxy-14-oxoseco-d-5β-androstane as inhibitors of Na+, K+-ATPase at the digitalis receptor

Mauro Gobbini; Paolo Barassi; Alberto Cerri; Sergio De Munari; Giorgio Fedrizzi; Marco Santagostino; Antonio Schiavone; Marco Torri; Piero Melloni


Journal of Medicinal Chemistry | 2000

17β-O-aminoalkyloximes of 5β-androstane-3β, 14β-diol with digitalis-like activity : Synthesis, cardiotonic activity, structure-activity relationships, and molecular modeling of the Na+, K+-ATPase receptor

Alberto Cerri; Nicoletta Almirante; Paolo Barassi; Alessandra Benicchio; Giorgio Fedrizzi; Patrizia Ferrari; Rosella Micheletti; Luisa Quadri; Enzio Ragg; Roberto Rossi; Marco Santagostino; Antonio Schiavone; Fulvio Serra; Maria Pia Zappavigna; Piero Melloni


Synlett | 1999

β-Tosylhydrazono Phosphonates in Organic Synthesis. An Unambiguous Entry to Polysubstituted Pyrazoles

Nicoletta Almirante; Alessandra Benicchio; Alberto Cerri; Giorgio Fedrizzi; Giuseppe Marazzi; Marco Santagostino


Synlett | 1997

3αβ-Hydroxy-7αβ-methylperhydroinden-4-one Derivatives en route to Analogues of Cardenolides

Marco Frigerio; Marco Santagostino; Simona Sputore


Archive | 2000

Process for preparing R-(-)carnitine from S-(-)-chlorosuccinic acid or from a derivative thereof

Piero Melloni; Alberto Cerri; Marco Santagostino


Archive | 1994

Process for the oxidation of primary and secondary alcohols to aldehydes and ketones and for the oxidation of 1,2-diols to alpha -ketols and alpha -diketones

Marco Frigerio; Marco Santagostino; Simona Sputore

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