Maria Augusta Bessa Rebelo

Parental age as a risk factor for non-syndromic oral clefts: A meta-analysis

OBJECTIVES A meta-analysis was conducted to assess the relationship between parental age and the occurrence of non-syndromic oral clefts. The questions addressed if younger or older mothers and fathers have an increased risk of having a child with non-syndromic oral clefts. DATA Data from cohort studies, case-control, cross-sectional and prevalence studies in which the association between parental age and oral clefts was investigated were analysed. Only studies on oral clefts not associated with syndromes or other anomalies were considered. SOURCES An electronic literature search were conducted in Medline, Embase, LILACS, SciELO, SCOPUS and the Cochrane library databases to identify original research published until November 2010. References of the selected articles were also searched. STUDY SELECTION The initial database search identified 4623 citations and according to eligibility criteria 80 articles were submitted to quality assessment. In 13 studies measures of association could be extracted for meta-analysis. CONCLUSION Our findings suggest that fathers forty years of age or older had a 58% higher probability of having a child with cleft palate compared to those aged between 20 and 39 years. The probability of mothers aged between 35 and 39 years having a child with cleft palate was 20% higher in comparison with those between 20 and 29 years-old, whilst for those aged 40 years or more this probability was 28% higher compared to those aged between 20 and 29 years. Mothers aged 40 years or over were 1.56 times more likely to have a newborn with cleft lip with or without palate compared to those aged between 20 and 29 years. No evidence of association between early maternal and paternal age with occurrence of oral clefts was observed.

Quality of life related to oral health: contribution from social factors

UNLABELLED Sociodental indicators have been widely used in epidemiological research related to oral health, as they add the dimension of the impact of oral health on the quality of life of individuals and populations. Various studies have been done in order to validate new instruments to assess these subjective perceptions, however, the association between social parameters and impact on oral health-related quality of life (OHRQoL) has not been systematically studied, thus there is still doubt as to the role of the main social variables as OHRQoL impact modulators. This study aims to systematically review the literature in order to evidence the association between six social parameters and OHRQoL. Based on six exclusion criteria, the literature search revealed 40 eligible publications for analyses. The frequency of expected (positive) association between the social parameters and OHRQoL was greater than the non-expected (negative) associations for the six parameters. CONCLUSIONS The social conditions most clearly associated with the perception of negative impact on OHRQoL were: women, with poor education and low income, immigrants or people belonging to minority ethnic groups.

Evaluation of the fluoride stability of dentifrices sold in Manaus, AM, Brazil.

The minimum requirement for the anti-caries effect of a dentifrice is the presence of available and stable fluoride in the formulation. The concentration of available fluoride in the major dentifrices sold in Brazil has been reported, but few data have been published about its stability, which is temperature-dependent. Thus, the aim of this study was to evaluate the concentration and stability of fluoride in dentifrices sold in Manaus, AM, Brazil, which is a typical tropical city. The concentrations of total fluoride, total soluble fluoride, MFP, and of insoluble fluoride of six Brazilian dentifrices and an imported one were analyzed. The analyses were made when the dentifrices were purchased and during a year of storage at room temperature (28.9 1.16 C) and under refrigeration (26.3 0.88 C). The analyses were performed using an ion specific electrode Orion 96-09. At the time of purchase, all the dentifrices analyzed showed more than 1,000 ppm (mug F-/g; w/w) of soluble fluoride. However, in most of them, this form of fluoride was not shown to be stable. The highest loss of soluble fluoride was found for storage at room temperature, reaching up to 40%. Although all dentifrices comply with the Brazilian guidelines with regard to the concentration of total fluoride (maximum of 0.15%), the instability of soluble fluoride observed in some of them can impair their anti-caries effect and this condition is not contemplated in the Governmental rules.

Psychometric properties of the OHIP-14 and prevalence and severity of oral health impacts in a rural riverine population in Amazonas State, Brazil

The objectives of this study were: (1) test the psychometric properties of OHIP-14 in a rural population; and (2) compare the oral health impacts in two riverine communities in the Brazilian Amazon that were living at different distances from an urban center. Data were obtained from a cross-sectional study in a consecutive sample (n = 126). The validity was assessed through the association of OHIP with clinical and subjective variables, which showed a more significant association with: pain, caries, need of extraction or endodontic treatment; than with tooth loss, periodontal disease or need of prostheses. The stability and internal consistency were good (ICC = 0.97; Cronbachs alpha = 0.89). The prevalence of oral impacts was greater in the community far from the urban center [70.3 (59.9-80.7)] than in the community closer to it [44.3 (30.7-57.7)], and in women [66.7 (56.0-77.3)] in comparison with men [49.1 (35.3-62.7)]. The OHIP-14 adapted to rural populations in Amazonas State was valid, reproducible, and consistent. There was high prevalence of impacts, especially for riverine communities that lived far from urban centers.

Measurement of health-related and oral health-related quality of life among individuals with nonsyndromic orofacial clefts: a systematic review and meta-analysis.

Objective To compare health-related quality of life and oral health–related quality of life between nonsyndromic individuals with and without cleft lip and/or cleft palate and to identify the most affected quality of life dimensions in individuals with cleft lip and/or palate. Design Systematic review and meta-analysis were conducted. Of the 314 identified citations, 23 articles were submitted to quality assessment. Data from nine studies on health-related quality of life and six on oral health–related quality of life were extracted for meta-analysis. Main Outcome Measures Pooled mean differences of health-related quality of life between adults with and without cleft lip and/or palate, pooled means of health-related quality of life dimensions of children and adults with cleft lip and/or palate and oral health–related quality of life dimensions of children and adolescents with cleft lip and/or palate with a 95% confidence interval were calculated. Results Quality assessment revealed methodological differences between studies. Lack of subgroup stratification and absence of control for confounders were the main limitations. Heterogeneity was detected on the comparison of oral health–related quality of life and health-related quality of life between children with and without cleft lip and/or palate, and oral health–related quality of life between adolescents with and without cleft lip and/or palate. A random-effect model showed a significant difference on health-related quality of life between adults with and without cleft lip and/or palate (mean difference = 0.10; 95% confidence interval, 0.16 to 0.05). Psychological health (mean, 78.9; 95% confidence interval, 70.1 to 87.7) and vitality (mean, 68.1; 95% confidence interval, 48.0 to 88.1) were the most affected health-related quality of life dimensions in children and adults with cleft lip and/or palate, respectively. Means of health-related quality of life dimensions in children and adults with cleft lip and/or palate and oral health–related quality of life in children and adolescents with cleft lip and/or palate varied yet did not differ in indirect comparisons. Conclusion The presence of cleft lip and/or palate negatively affected the health-related quality of life of adults, mainly on psychosocial dimensions.

Dental caries and gingivitis among 15 to 19 year-old students in Manaus, AM, Brazil

In the light of the scarcity of epidemiological studies on the oral health of the general population within the context of the Amazon region, this study aimed to estimate the prevalence of dental caries and gingivitis, as well as to evaluate the need for restorative treatment, among school students aged 15 to 19 years in the city of Manaus, AM, Brazil. A cross-sectional study was carried out on a sample of 889 students from within city limits who were enrolled in 26 public and private schools. Dental examinations were performed to obtain the DMFT index (decayed, missing and filled teeth) as well as to determine the treatments needed. The gingival index (Lõe & Silness) was used to classify gingivitis. The intra-examiner diagnostic concordance was 94% and the Kappa statistic was 0.91. The DMFT index found was 4.65 (+/- 0.12), without significant difference between the sexes or skin color groups. The prevalence of dental caries was 87.4%. Restoration of a dental surface was the greatest need (59.3%). Slight gingival inflammation was present in 78.5% and gingival bleeding following probing occurred in 53.3%. Although the DMFT index was lower than that observed for the northern region of Brazil, restorative dental services are lacking for this population. Additional studies are suggested to better understand the differences found.

Condição de saúde bucal em idosos residentes no município de Manaus, Amazonas: estimativas por sexo

OBJETIVO: Caracterizar, segundo o sexo, as condicoes de saude bucal em idosos residentes no municipio de Manaus, AM. METODOS: Estudo seccional de base populacional com 667 individuos com idade entre 65-74 anos, aleatoriamente selecionados. As informacoes demograficas e socioeconomicas foram obtidas atraves de entrevista. O exame bucal para carie, edentulismo, uso e necessidade de proteses foi conduzido de acordo com as normas da OMS. RESULTADOS: Participaram do estudo 206 homens e 461 mulheres, com idade media de 69,2 anos, e 71,8% se declararam de cor parda. Em media, os sujeitos apresentaram 4,6 anos de estudo e renda familiar de R

Cárie dentária e necessidade de tratamento odontológico entre os índios Baniwa do Alto Rio Negro, Amazonas

1586,27. O indice de dentes cariados, perdidos e obturados foi de 29,0 ± 4,3, com predominio do componente perdido (95%). A media de dentes por individuo foi de 4,1 ± 5,7 e a prevalencia de edentulismo foi de 52,2%, sendo que apenas 3% dos idosos apresentaram 20 dentes ou mais. O uso de protese total superior e inferior foi observado em 79,2% e 37,1%, respectivamente, e a necessidade de protese total foi de 42,6% para o arco superior e 34,7% para o inferior. Idosos do sexo masculino apresentaram menor indice de dentes cariados, perdidos e obturados, mais dentes e menos edentulismo em comparacao com o sexo feminino. O uso de protese total superior e inferior foi maior nas idosas, enquanto a necessidade de protese unitaria ou parcial superior e inferior foi maior nos idosos. CONCLUSAO: As condicoes de saude bucal dos idosos em Manaus caracterizaram-se pela elevada ocorrencia de perda dentaria, especialmente entre as mulheres. As taxas de uso e a necessidade de protese total foram elevadas e diferentes segundo sexo.

Oferta e utilização de serviços de saúde bucal no Amazonas, Brasil: estudo de caso em população ribeirinha do Município de Coari

Epidemiologic research conducted with Indian communities in Brazil has shown strong correlation between the deterioration of their oral health and the consumption of industrial products, sugar in particular, added to the lack of structure of oral health care. This study was carried out among the Baniwa Indians from the Tunui-Cachoeira region, Sao Gabriel da Cachoeira, Northwestern Amazon, Brazil. A cross-sectional survey was conducted according to the criteria established by the WHO, focusing on dental caries and need for dental treatment. A total of 590 individuals were examined (49.2% of the population older than 2 years). The mean numbers of teeth with caries were 6.0, 8.2 and 22.1 in the age groups 12-14, 15-19 and more than 50 years respectively. In children with deciduous dentition the highest mean value of decayed, missing and filled teeth (5.3) was observed in children age 5. From the total of examined people, 73.6% showed some need for surgery-restoration. The individuals between 15-19 years of age show the highest need for restorations. The DFMT index for the Baniwa can be considered high. The results show that it is necessary to expand public health control measures related to oral heath, taking into consideration the complex socio-cultural reality of the Northwestern Amazon region.

Prevalência e gravidade da cárie dentária e necessidade de tratamento em crianças de 12 anos de município de pequeno porte inserido no contexto amazônico

This case study described the conditions in the provision and utilization of dental services in two riverine populations in the municipality (county) of Coari, Amazonas State, Brazil. Structured questionnaires were applied to individuals 18 years and older to measure dental services utilization rates. Semi-structured interviews were also conducted with key informants to characterize the provision of such services. Although the bivariate analysis did not detect any statistically significant differences, residents of the area farthest from the county seat had gone more time since their last dental visit and received less care from public health services and riverboat clinics. The qualitative analysis showed: no permanent dental services in the communities; sporadic services provided by riverboat clinics, with less frequent visits to the remotest community; high transportation cost for river-dwellers to seek treatment in the county seat; and dental treatment focused on pain control, mainly through tooth extraction. Limited access to dental services for riverine populations highlights the need to implement comprehensive health promotion measures and expand the availability of services.