Marshall P. Solomon

Malignant fibrous histiocytoma of the soft tissues of the mandible

Abstract This article presents, insofar as we know, the sixth report of a case of malignant fibrous histiocytoma occurring in the paramandibular tissues. The biologic behavior and the gross and microscopic pathologic features of this lesion are discussed with reference to the recent literature on malignant fibrous histiocytoma.

Intraoral papillary squamous cell tumor of the soft palate with features of sialadenoma papilliferum‐? malignant sialadenoma papilliferum

An unusual, recurring, squamous papillary tumor involving and possibly arising from minor salivary gland excretory ducts in the palate is presented. Similarity to sialadenoma papilliferum and upper respiratory tract papillomatosis is noted. A paraglandular cystic mass with some resemblance to the palatal lesion, and a solitary lymph node with papillary squamous epithelial deposits was found in a radical neck dissection. We suggest that the lymph node lesion represents a metastasis which may have arisen from the palatal lesion, and therefore propose the concept of a possible malignant analogue of sialadenoma papilliferum. Cancer 42:1859–1869, 1978.

Peripheral odontogenic tumor with ghost-cell keratinization. A histologic, fluorescent microscopic, and ultrastructural study.

Abstract An unusual peripheral odontogenic lesion is described. Ultrastructural studies revealed a pattern of calcification that had never before been described in epithelial tissues.

Metastatic malignancy in the submandibular gland.

Metastatic disease in the major salivary glands has been observed and reported in the literature. Often the site of origin of the primary tumor is the skin or mucosal lining of the head and neck structures, and the primary tumors most commonly are melanomas or squamous-cell carcinomas. The most frequently involved salivary gland is the parotid. The submandibular and sublingual glands are rarely involved by mestastatic disease. Secondary lesions arising from distant primary tumors may occasionally involve the parotid gland, but they are extremely rare in the other major salivary glands. The second reported case of metastatic carcinoma in the submandibular gland is presented here. Our case and the previously reported case are similar in that both primary tumors originated in the breast. The clinical and morphologic features are reviewed.

Intraoral submucosal pseudosarcomatous fibromatosis.

Abstract Presented is a case of intraoral pseudosarcomatous fibromatosis. The clinical, gross, and microscopic aspects are illustrated, and comparison is made to previously documented lesions in the oral cavity. Histologic evaluation of fibroproliferative lesions and their subsequent behavior and possible etiology are discussed.

South American blastomycosis of the maxilla: report of a case

An unusual case of localized South American blastomycosis of the maxilla, occurring in the United States, is reported. Clinical presentation, diagnosis, treatment, and reconstruction are reviewed.

Calcifying epithelial odontogenic tumor. A histologic, histochemical, fluorescent, and ultrastructural study.

A previously unreported calcifying epithelial odontogenic tumor (CEOT; Pindborg tumor) occurring in a Negro patient is presented. Only 12 per cent of these neoplasms have been found in nonwhite patients. Ultrastructural and histochemical studies indicated that the amorphous, acellular, eosinophilic substance present within the tumor was not amyloid. The presence of only sparse calcifications is an unusual histologic variant. No relationship between neoplasm and reduced enamel epithelium could be demonstrated.

Metastatic ameloblastoma to the cervical lymph nodes: a case report and review of literature.

Ameloblastomas make up 1 % of all tumors found in the oral cavity. 1 They occur 80% of the time in the mandible, and 20% of the time in the maxilla.2 - 5 Ameloblastomas are benign tumors that are locally aggressive. Recurrence rates have been reported as high as 50% to 72%, depending on treatment modality. 1 Malignant ameloblastoma is defined as a histologically benign-appearing ameloblastoma with metastasis. 2 Metastasis most commonly occurs in the lungs (75% to 88% of cases) and lymph nodes (15% to 27% of cases), but is also seen in the liver, brain, bones, kidneys, and intestines. 3 It is theorized that metastatic spread occurs via 3 routes: lymphatics, hematogenous, and aspiration. 6,7 .

Sebaceous carcinoma of the oral cavity: a case report and review of the literature.

We report the clinical and pathologic features of an intraoral sebaceous carcinoma and review the literature. The intraoral buccal mucosal tumor from a 50-year-old man was a poorly differentiated carcinoma with sebaceous differentiation and expression of androgen receptor. Fordyce granules and a minor salivary gland with a duct were identified in vicinity to the tumor. We discuss the differential diagnosis and histogenesis. The patient underwent surgery and adjuvant radiation therapy.

Mucoepidermoid Carcinoma Arising in a Background of Sialadenoma Papilliferum: A Case Report

Sialadenoma papilliferum is a rare tumor, primarily of minor salivary gland origin, first described by Abrams and Finck (Cancer 24:1057–63, 1969). It is both an exophytic and endophytic papillary lesion histologically resembling syringocystadenoma papilliferum of sweat gland. The tumor is considered benign although rare recurrent cases have been reported. Three cases of malignant transformation of sialadenoma papilliferum have been described in the literature. We report a high grade mucoepidermoid carcinoma arising in a background of sialadenoma papilliferum, at the base of the tongue, an unusual location for minor salivary gland neoplasms. Eleven months after excision and nodal dissection, there is no evidence of recurrence or metastasis.