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Martha A. Warpehoski

Pfizer

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Publication

Featured researches published by Martha A. Warpehoski.

Chemical Research in Toxicology | 1988

Sequence selectivity of DNA covalent modification

Martha A. Warpehoski; Laurence H. Hurley

Journal of Medicinal Chemistry | 1988

Stereoelectronic factors influencing the biological activity and DNA interaction of synthetic antitumor agents modeled on CC-1065

Martha A. Warpehoski; I. Gebhard; Robert C. Kelly; W. C. Krueger; L. H. Li; J. P. McGovren; M. D. Prairie; Nancy Anne Wicnienski; W. Wierenga

Journal of Medicinal Chemistry | 2004

3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 1. Lead finding

Paolo Pevarello; Maria Gabriella Brasca; Raffaella Amici; Paolo Orsini; Gabriella Traquandi; Luca Corti; Claudia Piutti; Pietro Sansonna; Manuela Villa; Betsy S. Pierce; Maurizio Pulici; Patrizia Giordano; Katia Martina; Edward L. Fritzen; Richard A. Nugent; Elena Casale; Alexander D. Cameron; Marina Ciomei; Fulvia Roletto; Antonella Isacchi; Gianpaolo Fogliatto; Enrico Pesenti; Wilma Pastori; Aurelio Marsiglio; Karen L. Leach; Paula Munns Clare; Francesco Fiorentini; Mario Varasi; and Anna Vulpetti; Martha A. Warpehoski

Biochemistry | 1988

Molecular basis for sequence-specific DNA alkylation by CC-1065

Laurence H. Hurley; Chongmok Lee; McGovren Jp; Martha A. Warpehoski; Mark A. Mitchell; Robert C. Kelly; Paul Adrian Aristoff

Journal of the American Chemical Society | 1990

Sequence specificity of DNA alkylation by the unnatural enantiomer of CC-1065 and its synthetic analogues

Laurence H. Hurley; Martha A. Warpehoski; J. Chong-Soon Lee; B. Patrick McGovren; Terrence A. Scahill; Robert C. Kelly; Mark A. Mitchell; Nancy Anne Wicnienski; Ilse Gebhard; Paul D. Johnson; V. Susan Bradford

Biochemistry | 1992

Reversibility of the covalent reaction of CC-1065 and analogues with DNA.

Martha A. Warpehoski; Donald E. Harper; Mark A. Mitchell; Thomas J. Monroe

Journal of the American Chemical Society | 1995

Enzyme-like Rate Acceleration in the DNA Minor Groove. Cyclopropylpyrroloindoles as Mechanism-Based Inactivators of DNA

Martha A. Warpehoski; Donald E. Harper

Archive | 1998

α-hydroxy, -amino, and halo derivatives of β-sulfonyl hydroxamic acids as matrix metallopropteinases inhibitors

Martha A. Warpehoski; Mark A. Mitchell; Donald E. Harper; Linda L. Maggiora

Archive | 1998

ALPHA-HYDROXY,-AMINO AND -FLUORO DERIVATIVES OF BETA-SULPHONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS

Martha A. Warpehoski; Mark A. Mitchell; Donald E. Harper; Linda L. Maggiora

Biochemical Pharmacology | 1988

Reaction of CC-1065 and select synthetic analogs with DNA

Laurence H. Hurley; Chong Soon Lee; J. Patrick McGovren; Martha A. Warpehoski; Mark A. Mitchell; Robert C. Kelly; Paul Adrian Aristoff

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Betsy S. Pierce

Pfizer

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Edward L. Fritzen

Upjohn

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Gabriella Traquandi

Upjohn

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Mario Varasi

Pharmacia

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Paolo Pevarello

Pharmacia

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Paolo Orsini

National University of Ireland

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Mark A. Mitchell

Upjohn

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Donald E. Harper

Upjohn

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Laurence H. Hurley

University of Arizona

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Robert C. Kelly

Pfizer

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