Donald E. Harper

Reversibility of the covalent reaction of CC-1065 and analogues with DNA.

Enzyme-like Rate Acceleration in the DNA Minor Groove. Cyclopropylpyrroloindoles as Mechanism-Based Inactivators of DNA

'Beta'-sulfonyl hydroxamic acids as matrix metalloproteinases inhibitors

α-hydroxy, -amino, and halo derivatives of β-sulfonyl hydroxamic acids as matrix metallopropteinases inhibitors

Thiadiazolyl(thio)ureas useful as matrix metalloprotease inhibitors

Thiadiazole derivatives useful for the treatment of diseases related to connective tissue degradation

ALPHA-HYDROXY,-AMINO AND -FLUORO DERIVATIVES OF BETA-SULPHONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS

Chemical modification of steffimycin B.

β-sulfonyl hydroxamic acids

Alpha-hydroxy, -amino and -halo derivatives of beta-sulfone hydroxamates as matrix metalloproteinase inhibitors