Masayuki Nakata

Estimating Myocardial Damage and the Need for Surgery in Patients With Valvular Heart Disease by Tl-201 SPECT

Left ventricular myocardial disorders due to volume overload were investigated by Tl-201 myocardial SPECT (Tl-201 SPECT) in patients with aortic or mitral regurgitation, and its utility for timing cardiac valve replacement was studied. There were significant correlations between Tl-201 scores and electrocardiographic changes and the New York Heart Association classification. There also were favorable correlations between Tl-201 scores and the left ventricular end-diastolic dimension and between Tl-201 scores and left ventricular ejection fraction, and a close relationship between the presence of a left ventricular myocardial disorder and left ventricular diameter. These results suggest that myocardial perfusion abnormalities and left ventricular myocardial disorders may accompany left ventricular dilatation owing to volume overload. After valve replacement, left ventricular end-diastolic dimension normalized, and Tl-201 scores improved slightly, suggesting normalization of myocardial perfusion. When moderate or more severe Tl-201 defects are present on Tl-201 SPECT images, in addition to inverted Tl-201 waves on the electrocardiogram or a left ventricular end-diastolic dimension of 65 mm or more, cardiac valve replacement should be considered.

The Influence of Endoscopic Injection Sclerotherapy on Organs Surrounding the Esophagus

Abstract: Endoscopic injection sclerotherapy (EIS) is widely accepted as a means of treating esophageal varices. However, various complications of EIS have been reported. To investigate the cause of chest complications after EIS, chest CT and bronchofiberscopy (BF) were carried out in patients undergoing EIS. A contrast medium was added to the sclerosant in a 1: 4 ratio, and a chest CT examination was performed 30 minutes after the EIS procedure. BF was performed before and after EIS.

Hepatocellular Carcinoma with Metastasis to the Duodenum: —A Case Report—

Abstract: A case of hepatocellular carcinoma with metastasis to the duodenum is reported on together with a review of the literature. A 61‐year‐old male was admitted with hematemesis and melena. An endoscopic examination revealed a large hemorrhagic ulcer at the duodenal bulbi. A biopsied specimen taken from the bottom of the ulcer revealed an infiltrating hepatocellular carcinoma. The postmortem examination revealed a hepatocellular carcinoma with metastasis in the duodenum. This is the third report of hepatocellular carcinoma with metastasis in the duodenum.

Patterns of recurrence in lung cancer responders treated with radiotherapy-chemotherapy.

非観血的治療により導入された肺癌奏効例について再発の病態を検討した.初発両発部位は小細胞癌では脳, 非小細胞癌では胸部局所に最も多くみられた.中間奏効期間は小細胞癌4ヵ月, 非小細胞癌7ヵ月で, 後者で奏効期間の有意の延長がみられた.また小細胞癌, 非小細胞癌ともにCR例ではFR例に比し奏効期間の有意の延長がみられた.小細胞癌, 非小細胞癌いずれも大部分の症例が1年以内に再発した.