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Dive into the research topics where Michael J. Seatter is active.

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Featured researches published by Michael J. Seatter.


Proceedings of the Nutrition Society | 1996

Hormonal regulation of the insulin-responsive glucose transporter, GLUT4: some recent advances.

Callum Livingstone; Fiona J. Thomson; Margaret I. Arbuckle; Ian W. Campbell; Thomas J. Jess; Susan Kane; Colin Moyes; Lisa M. Porter; Jacqueline E. Rice; Michael J. Seatter; Gwyn W. Gould

gradient chimique a travers la membrane de la cellule. I1 est possible de proposer une explication cette diversit6 d’expression basee sur l’analyse des proprietes cinetiques et fonctionnelles de ces diffirents isoformes. Ainsi, on pense que GLUT1 est impliquC dans le transport du glucose 2 travers les barrikres entre le sang et les organes tels que la rCtine, et a travers la barrih-e entre le sang et le cerveau; il est aussi impliquC dans le maintien de niveaux basals ou d’entretien de I’activitC de transport du glucose dans beaucoup de types de cellules, sinon dans tous. GLUT;! est un transporteur a haute capacitC et


Biochemical Journal | 1993

Kinetic analysis of the liver-type (GLUT2) and brain-type (GLUT3) glucose transporters in Xenopus oocytes: substrate specificities and effects of transport inhibitors.

Caroline A. Colville; Michael J. Seatter; Thomas J. Jess; Gwyn W. Gould; Helen M. Thomas


Biochemistry | 1998

QLS Motif in Transmembrane Helix VII of the Glucose Transporter Family Interacts with the C-1 Position of d-Glucose and Is Involved in Substrate Selection at the Exofacial Binding Site†

Michael J. Seatter; De la Rue Sa; Lisa M. Porter; Gwyn W. Gould


Biochemistry | 1996

Structure-function analysis of liver-type (GLUT2) and brain-type (GLUT3) glucose transporters: expression of chimeric transporters in Xenopus oocytes suggests an important role for putative transmembrane helix 7 in determining substrate selectivity.

Margaret I. Arbuckle; Susan Kane; Lisa M. Porter; Michael J. Seatter; Gwyn W. Gould


Biochemical and Biophysical Research Communications | 1997

FUNCTIONAL STUDIES OF HUMAN GLUT5 : EFFECT OF PH ON SUBSTRATE SELECTION AND AN ANALYSIS OF SUBSTRATE INTERACTIONS

Susan Kane; Michael J. Seatter; Gwyn W. Gould


Biochemical Journal | 1993

Analysis of the structural requirements of sugar binding to the liver, brain and insulin-responsive glucose transporters expressed in oocytes.

Caroline A. Colville; Michael J. Seatter; Gwyn W. Gould


Biochemistry | 1997

Structure-function studies of the brain-type glucose transporter, GLUT3: alanine-scanning mutagenesis of putative transmembrane helix VIII and an investigation of the role of proline residues in transport catalysis.

Michael J. Seatter; Susan Kane; Lisa M. Porter; Margaret I. Arbuckle; Derek R. Melvin; Gwyn W. Gould


Pharmaceutical biotechnology | 2002

The Mammalian Facilitative Glucose Transporter (GLUT) Family

Michael J. Seatter; Gwyn W. Gould


Biochemical Society Transactions | 1992

Tissue-specific expression of facilitative glucose transporters: a rationale.

Helen M. Thomas; Alison M. Brant; Caroline A. Colville; Michael J. Seatter; Gwyn W. Gould


Biochemical Society Transactions | 1997

Structure-function studies of the brain-type glucose transporter, GLUT3: alanine-scanning mutagenesis of putative transmembrane helix 8.

Michael J. Seatter; Susan Kane; Lisa M. Porter; Gwyn W. Gould

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