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Dive into the research topics where Norman F. Sheppard is active.

Publication


Featured researches published by Norman F. Sheppard.


Nature Biotechnology | 2006

Chronic, programmed polypeptide delivery from an implanted, multireservoir microchip device

James H. Prescott; Sara A. Lipka; Samuel P. Baldwin; Norman F. Sheppard; John M. Maloney; Jonathan R. Coppeta; Barry Yomtov; Mark A. Staples; John T. Santini

Implanted drug delivery systems are being increasingly used to realize the therapeutic potential of peptides and proteins. Here we describe the controlled pulsatile release of the polypeptide leuprolide from microchip implants over 6 months in dogs. Each microchip contains an array of discrete reservoirs from which dose delivery can be controlled by telemetry.


Archive | 2003

Affinity binding-based system for detecting particulates in a fluid

Norman F. Sheppard; Alec Mian; Gregory J. Kellogg; Stephen G. Kieffer-Higgins; Bruce L. Carvalho


Archive | 2002

Flexible microchip devices for ophthalmic and other applications

John T. Santini; Michael J. Cima; Robert S. Langer; Dennis Ausiello; Norman F. Sheppard; Stephen J. Herman


Archive | 2001

Microfluidics devices and methods for performing cell based assays

Bruce L. Carvalho; Norman F. Sheppard; Christina M. Feakes; Gregory J. Kellogg


Journal of Controlled Release | 2005

Electrothermally activated microchips for implantable drug delivery and biosensing.

John M. Maloney; Scott A. Uhland; Benjamin F. Polito; Norman F. Sheppard; Christina M. Pelta; John T. Santini


Archive | 2007

Device for the controlled exposure of reservoir-based sensors

John T. Santini; Norman F. Sheppard; Chung Chang Young; Robert S. Langer


Archive | 2001

USE OF VAPOR-DEPOSITED CONFORMAL COATINGS IN MICROFLUIDIC STRUCTURES

Norman F. Sheppard; Bruce L. Carvalho


Archive | 2005

Affinity based system for detecting particulates in a fluid

Norman F. Sheppard; Alec Mian; Gregory J. Kellogg; Stephen G. Kieffer-Higgins; Bruce L. Carvalho


Archive | 2006

Hermetically Sealed Devices for Controlled Release or Exposure of Reservoir Contents

Jonathan R. Coppeta; Scott A. Uhland; Benjamin F. Polito; Norman F. Sheppard; Christina M. Feakes; Douglas B. Snell; John T. Santini


Archive | 2007

Method of actuating implanted medical device

John T. Santini; Michael J. Cima; Robert S. Langer; Dennis Ausiello; Norman F. Sheppard

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