Rahmi Cubuk
Maltepe University
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Rahmi Cubuk.
Radiologia Medica | 2010
Rahmi Cubuk; Nuri Tasali; Burcu Narin; F. Keskiner; Levent Celik; Sefik Guney
PurposeWe aimed to analyse the influence of mammographic breast density on background enhancement (BE) at magnetic resonance (MR) mammography in preand postmenopausal women. In addition, we questioned predictability of contrast-enhancement dynamics of normal fibroglandular tissue (NFT) at MR mammography according to mammographic breast density.Materials and methodsTwenty-six patients (mean age 51.54±11.5 years; range 37–79 years) who underwent both MR mammography and conventional mammography were included in this retrospective study. Fourteen patients were premenopausal and 12 were postmenopausal. The ethics committee of our institution approved the study. The mammograms were retrospectively reviewed for overall breast density according to the four-point scale (I–IV) of the Breast Imaging Reporting and Data System (BI-RADS) classification. Two radiologists, who were unaware of the clinical data, separately assessed the MR mammography images. Images were assessed for enhancement kinetic features (enhancement kinetic curve and the early-phase enhancement rate) and BE. MR mammography and conventional mammography findings were compared according to BI-RADS breast density category and menopausal status.ResultsPercentage of increased signal intensity values during the first minute did not change according to mammographic breast density, and the mean early-phase enhancement rate scores were similar among breast density groups (p=0.942). There was no significant difference between pre- and postmenopausal groups. Enhancement kinetic features of the different groups based on BI-RADS breast density category and menopausal status were similar. There was no correlation between breast density and BE in either premenopausal (p=0.211) or in postmenopausal (p=0.735) groups.ConclusionsWe determined no correlation between mammographic breast density and so-called BE in MR mammography in either premenopausal or postmenopausal women. NFT at MR mammography cannot be predicted on the basis of mammographic breast density.RiassuntoObiettivoScopo del nostro studio è analizzare l’influenza della densità mammografica del seno sul background enhancement in risonanza magnetica, considerando donne in pre e post-menopausa. È stata inoltre valutata la prevedibilità delle dinamiche di contrast-enhancement del tessuto fibroghiandolare normale (NFT) in RM, in rapporto alla densità mammografica del seno.Materiali e metodiIn questo studio retrospettivo sono state incluse 26 pazienti (media di età 51,54±11,5; range 37–79 anni), sottoposte sia a RM sia a mammografia convenzionale. Quattordici pazienti erano in premenopausa e dodici in post-menopausa. Lo studio è stato approvato dal comitato etico del nostro istituto. Gli esami sono stati analizzati retospettivamente per valutare la densità complessiva del seno, in accordo con la scala di quattro punti (I–IV) basata sulla classificazione BI-RADS (Breast Imaging Repotring and Data System). Due radiologi, senza conoscere i dati clinici, separatamente, hanno valutato le immagini RM. Sono state analizzate le caratteristiche cinetiche di enhancement (curva della cinetica di enhancement e velocità della fase precoce di enhancement) e il background enhancement. I rilievi ottenuti in RM e in mammografia convenzionale sono poi stati comparati con la classificazione BI-RADS, e lo stato menopausale.RisultatiLa percentuale di valori con intensità del segnale aumentato durante i primi minuti non è risultata variare in rapporto alla densità mammografica del seno, e i valori medi di velocità di enhancement in fase precoce sono risultati simili tra i gruppi di densità del seno (p=0,942). Non sono emerse differenze significative tra gruppi pre e post-menopausa. Le cinetiche di enhancement dei differenti gruppi basati sulla classificazione di densità del seno (BI-RADS) e sullo stato menopausale, sono risultati simili. Non è stata evidenziata correlazione tra densità mammaria e background enhancement nei gruppi premenopausa (p=0,211),o postmenopausa (p=0,735).ConclusioniNon abbiamo rilevato correlazione tra la densità del seno in mammografia e il cosiddetto background enhancement in risonanza magnetica, né per quanto riguarda donne in pre-menopausa, né in postmenopausa. Il tessuto fibroghiandolare in RM non può essere correlato alla densità mammaria mammografica.
European Journal of Radiology | 2010
Rahmi Cubuk; Nuri Tasali; S. Aydin; B. Saydam; T. Sengor
OBJECTIVE The purpose of this study was to investigate the diagnostic value of dynamic MRI dacryocystography (dMR-DCG) for the assessment of nasolacrimal drainage system (NLDS). METHODS The study population consisted of 35 patients with a history of epiphora. Each patient underwent bilateral dMR-DCG and conventional dacryocystography (DCG) to assess the NLDS. Two radiologists, who were unaware of the clinical data, evaluated the images separately for the level of obstruction at the nasolacrimal passage and the presence or absence of lacrimal sac dilatation. The findings from the dMRI-DCG and DCG images were compared. DCG was considered to be the gold standard imaging technique. RESULTS dMRI-DCG had a sensitivity of 90.5% and a specificity of 89.3% to detect nasolacrimal passage. In 24 out of 70 NLDS that were assessed, there was 100% agreement between the dMRI-DCG and DCG images in the detection of the obstructed level in the nasolacrimal pathway. The lacrimal sac dilatation finding detected by DCG was not observed by dMRI-DCG in only two patients, in whom there was a prior history of dacryocystorhinostomy (DCR) operation. These findings suggest that dMRI-DCG has 94.3% sensitivity and 100% specificity for the diagnosis of lacrimal sac dilatation. CONCLUSION dMRI-DCG is an easily performed, minimally invasive imaging technique to identify the presence or absence of obstruction and its level, and lacrimal sac dilatation in the evaluation of NLDS. dMRI-DCG does not require the use of contrast material and ionizing radiation and provides functional information by depicting dynamic behaviour. Thus, dMRI-DCG could be useful as a reliable diagnostic imaging technique in many patients prior to surgery.
Sleep and Breathing | 2011
Nesrin Sarıman; Ender Levent; Rahmi Cubuk; Şirin Yurtlu; Fehime Benli Aksungar
PurposeHypoxia/reoxygenation episodes in obstructive sleep apnea (OSA) results in the alteration of the oxidative balance, leading to the development of inflammation. Airway wall thickening and inflammatory changes are suggested as a primary cause of the airway hyperresponsiveness in asthmatics. Bronchial hyperreactivity (BH) may also occur in patients with OSA. We investigated the presence of BH and airway wall thickness in OSA and correlations with inflammatory markers.Materials and methodsSixteen OSA patients and ten controls without allergic diseases were prospectively studied. Plasma pro-B-type natriuretic peptide (pro-BNP), fibrinogen, D-dimer, α1-antitrypsin, and high-sensitive C-reactive protein levels were measured. Airway wall thickness was evaluated with high-resolution CT, and BH was assessed by giving each subject a methacholine challenge test.ResultsIn OSA patients, bronchial wall thickness, fibrinogen, D-dimer, α1-antitrypsin, high sensitive C-reactive protein, and pro-BNP levels were significantly greater than those in control subjects. Among the 16 patients, three had BH on methacholine challenge. Bronchial wall thickness(mm) was positively correlated with apnea–hypopnea index (AHI: number of apneas + hypopneas/hour of sleep), BMI, respiratory arousal index, nocturnal oxygen desaturation (NOD) duration (time in minutes with a nocturnal arterial oxygen saturation of <90% during sleep), and α1-antitrypsin levels. NOD duration also correlated with pro-BNP and fibrinogen levels.ConclusionsIn OSA patients, walls of central airways were thicker than normal subjects. BH may have occurred in OSA patients. NOD duration correlated with inflammatory parameters and oxygen desaturation index 3% had an effect on the thickness of bronchial walls. But overall, AHI was found to be the only independent predictor of bronchial wall thickness.
Journal of Thyroid Research | 2013
Ugur Deveci; Fatih Altintoprak; Mahmut Sertan Kapakli; Manuk N. Manukyan; Rahmi Cubuk; Nese Yener; Abut Kebudi
Background. The use of a suction drain in thyroid surgery is common practice in order to avoid hematomas or seromas. The aim of this study was to determine the efficacy of routine drainage after thyroid surgery. Methods. In this prospective randomized trial, 400 patients who underwent either a total thyroidectomy or lobectomy for thyroid disorders were randomly allocated to either the nondrainage (group 1) or the drainage (group 2) group. The volume of fluid collection in the operative bed, postoperative pain, complications, and length of hospital stay were then recorded. Results. Both groups were homogeneous according to age, gender, thyroid volume, type of procedure performed, and histopathological diagnosis. After assessment by USG, no significant difference was found between the groups in the fluid collection of the thyroid bed (P = 0.117), but the length of hospital stay was significantly reduced in group 1 (P = 0.004). Conclusions. In our experience, the use of drain for thyroid surgery is not a routine procedure. However, it should be used in the presence of extensive dead space, particularly when there is retrosternal or intrathoracic extension, or when the patient is on anticoagulant treatment. This trial was registered with clinical Trials.gov NCT01771523.
European Journal of Radiology | 2012
Nuri Tasali; Rahmi Cubuk; M. Aricak; M. Ozarar; B. Saydam; H. Nur; Nermin Tuncbilek
PURPOSE We aimed to assess the contrast enhancement patterns of the retrodiscal tissue with dynamic contrast-enhanced MR imaging (DCE-MRI) with respect to different temporomandibular joint disc pathologies. Additionally, we questioned the relationship between the temporomandibular joint (TMJ) pain and the contrast enhancement pattern of the retrodiscal tissue regardless of the TMJ disc position. MATERIALS AND METHODS 52 joints of 26 patients (4 males and 22 females) who have pain in at least at one of their TMJ were included in this study. For the qualitative analysis, the joints were divided into four groups in terms of their disc positions: normal (1), partially displaced with or without reduction (2), totally dislocated with reduction (3) and totally dislocated without reduction (4). Besides, two different joint groups were constituted, namely the painful group and painless group according to the clinical findings without taking the TMJ disc positions into account. Quantitative analyses were made by means of measuring signal intensity ratios (SI) ratio at the retrodiscal tissue (from internal side and external side of the each joint) using DCE-MRI and these measurements were analyzed with paired samples t test to define the difference between the measurements. At the second stage, the time-dependent arithmetical mean values of the SI ratios were calculated for each joint group and significant differences between the groups were questioned using analysis of variance (ANOVA) test. Besides, painful and painless groups which were classified on the basis of the clinical data were compared according to the mean SI ratios found for each joint and the significant differences between these two groups were assessed by means of Students T test. The results were assessed in 95% confidence interval where the significance level was p<0.05. RESULTS A significant difference was observed between the internal and external contrast enhancement of the joints with partial displacement. Another significant difference was found between the average time versus SI ratio curves of the four groups. In consequence of the comparison made between the joints classified as painful and painless on the basis of the clinical data, one more significant difference was observed according to the mean SI ratios of the groups without taking the TMJ disc position into account. CONCLUSION The contrast enhancement patterns in the retrodiscal tissues of the painful joints showed significant differences in comparison with the painless joints. This result supports the hypothesis defending that inflammation and increased vascularity are responsible from the TMJ pain. Besides, the measurements from the retrodiscal tissues of the joints with partial displacement show significant difference between the signals of the displaced and non-displaced parts of the joints. Dynamic contrast-enhanced imaging revealed that different disc malpositions create different contrast enhancement patterns. On this basis, it is assessed that the types of the disc malpositions, which are believed to be acquired pathologies, are correlated with the retrodiscal inflammation degrees.
Clinical Imaging | 2009
Ayçe Atalay; Meral Kozakçıoğlu; Rahmi Cubuk; Nuri Tasali; Sefik Guney
AIM The aim of this study was to evaluate the effects of degenerative findings on the accuracy of readings obtained by dual-energy X-ray absorptiometry (DXA) in patients without osteoporosis. METHODS Twenty-four female patients who had undergone both DXA and lumbar magnetic resonance imaging were included in the study. CONCLUSION This study has demonstrated that degenerative radiologic changes, especially in the osteophyte area, affect bone mineral density measurements, so degeneration should be considered in the evaluation of this measurement.
Journal of Computer Assisted Tomography | 2015
Mehmet Mahir Atasoy; Nesrin Sarıman; Ender Levent; Rahmi Cubuk; Ömer Çelik; Attila Saygı; Işıl Atasoy; Sinan Şahin
Purpose To retrospectively evaluate the prognostic parameters of computed tomography (CT) pulmonary angiographic findings in nonsevere (hemodynamically stable) pulmonary embolism (PE) patients and to assess the predictive value of these parameters for mortality within 1 month of the initial diagnosis. Materials and Methods Retrospectively, 67 consecutive patients (28 men, 39 women; mean age, 63.25 ± 18 years) from 2 centers with nonsevere PE diagnosed using CT and a clinical evaluation were included in the current study. Using consensus reading, 2 readers blinded to the patients’ clinical outcomes quantified the right ventricle short axis to left ventricle short axis ratio in the axial plane, vascular measurements, reflux of contrast medium into the inferior vena cava and azygos vein, ventricular septal bowing, and clot load using the Qanadli scoring system. The Simplified Pulmonary Embolism Severity Index (sPESI) and pulmonary parenchymal findings were also evaluated. All CT pulmonary angiographic parameters were compared with the risk of death within 1 month using logistic regression analysis. Results Fifty-nine patients survived (88.1%), and 8 patients (11.9%) died because of PE. The sPESI and 2 parenchymal findings (multiple wedge-shaped opacities or consolidation accompanied by a wedge-shaped opacity) were significantly related to mortality. In the univariate analysis, neither the cardiovascular CT parameters nor the clot burden was significant between the survivors and nonsurvivors (P > 0.05). Conclusions In clinically nonsevere PE patients, the sPESI and significant parenchymal findings were the CT parameters related to 1-month mortality.
Acta Radiologica | 2011
Rahmi Cubuk; Alper Aydin; Nuri Tasali; Serdar Yilmazer; Levent Celik; Bahadir Dagdeviren; Sefik Guney
Background Imaging coronary venous systems to guide transcatheter cardiac interventions are becoming increasingly important, particularly in heart failure patients who are selected for cardiac resynchronization therapy (CRT). Failure of left ventricular (LV) lead placement during the procedure has been attributed to the inability to insert catheters into the coronary sinus and the lack of suitable side branches. Purpose To comparatively assess the value of a 64-detector MDCT examination in visualizing the cardiac veins and evaluating the morphological characteristics of the coronary venous system in patients with and without chronic systolic heart failure (SHF). Material and Methods A 64-detector MDCT examination of the heart was performed in 26 consecutive patients (five women, 21 men; mean age 57.80 ± 12.05 years; range 27–81 years) with chronic SHF. The morphological characteristics of the coronary venous system, such as the diameter, the distances between the venous tributaries, the angle and the tortuosity, were evaluated. The group was compared with a subgroup of 52 subjects without SHF (LV ejection fraction >40%) matched for age, sex, and the risk factors for coronary artery disease. Results The coronary sinus (CS), great cardiac vein (GCV), anterior interventricular vein (AIV), and posterior interventricular vein (PIV) were visualized in all 78 individuals. The posterior vein of the left ventricle (PVLV) (63/78), left marginal vein (LMV) (72/78), and the small cardiac vein (SCV) (50/78) were visualized in SHF and control patients (p = NS). The lengths between venous tributaries were higher (p > 0.05) and more dilated (P < 0.001 for CS, GCV, AIV, PVLV, LMV; p = 0.001 for PIV) in the cases with SHF compared with the control population. The angle between the CS-GCV axis and the venous branches was wider (p = 0.02 for LMV and PIV, p = 0.001 for PVLV) and did not have any correlation with the LV diameter in cases with SHF. There was no difference between the SHF and control groups in terms of the tortuosity of PVLV and LMV (p = NS). Conclusion The study demonstrated an increase in the diameters, lengths, and angulations with the CS-GCV axis of the coronary veins in cases with SHF. A 64-detector MDCT is a feasible tool for non-invasive evaluation of the coronary venous system and may provide considerable information regarding numbers and morphology of coronary veins before percutaneous transcatheter cardiac therapy.
The Eurasian Journal of Medicine | 2011
Tugrul Alici; Cem Zeki Esenyel; Meltem Esenyel; Yunus Imren; Semih Ayanoglu; Rahmi Cubuk
OBJECTIVE The geometry of the tibial plateau has a direct influence on the translation and the screw home biomechanics of the tibiofemoral joint. Little information on the relationship between the tibial slope and meniscal lesions is available. The objective of this retrospective study was to examine the effect of the tibial slope on the medial and lateral meniscus lesions in patients with intact ACLs. MATERIALS AND METHODS The MRIs and lat roentgenograms of 212 patients with meniscus lesions were examined to determine the possible effect of the tibial slope on meniscal tears. First, the anatomic axis of the proximal tibia was established. Then, the angle between the line drawn to show the tibial slopes (medial and lateral) and the line drawn perpendicular to the proximal tibial anatomic axis was established on MRI. The patients with previously detected meniscus lesions were classified into three categories: patients with only medial meniscal tear (Group 1, 90 patients); patients with only lateral meniscal tear (Group 2, 15 patients); and patients with both medial and lateral meniscal tear (Group 3, 19 patients). Group 4 had no meniscal tear (88 patients). The MRIs of the patients who had applied to the Orthopedic Outpatient Clinic with patellofemoral pain and no meniscal tear were included as the control group. RESULTS The average tibial slope of the medial tibial plateau was 3.18° in group 1, 3.64° in group 2, 3° in group 3, and 3.27° in group 4. The average tibial slope of the lateral tibial plateau was 2.88° in group 1, 3.6° in group 2, 2.68 in group 3, and 2.91 in group 4. The tibial slope on the medial tibial plateau was significantly larger than the lateral tibial plateaus in group 1 and group 4 (p<0.05). In group 2, there was no statistically significant difference between the tibial slopes of the two sides (p>0.05). In addition, the tibial slope on the lateral side of group 2 was significantly larger than that of groups 1, 3, and 4 (p<0.05). CONCLUSION An increase in the tibial slopes, especially on the lateral tibial plateau, seems to increase the risk of meniscal tear.
Radiologia Medica | 2011
Rahmi Cubuk; Nuri Tasali; S. Yilmazer; P. Gokalp; Levent Celik; Bahadir Dagdeviren; Sefik Guney
PurposeThe aim of the study was to investigate the relationship between image quality in 64-slice multidetector computed tomography (MDCT) and patients’ preimaging anxiety status and heart rate variability (HRV), and to evaluate the efficacy of an orally administered anxiolytic medication on HRV and image quality.Materials and methodsSixty patients [14 women, 46 men; mean age 52.53±10.55 (SD), range 33–78 years] were studied. Anxiety levels were assessed with the State-Trait Anxiety Inventory 60 min before the procedure. The participating patients were randomly assigned to one of the two study groups: a control group (no medication administered for anxiety reduction) and an anxiolytic medication group, with 30 patients in each group. The presence of motion artefacts and image quality for each coronary artery segment were evaluated using a four-point grading system. To estimate HRV, the duration of each heartbeat during MDCT data acquisition was measured in each patient.ResultsA moderate correlation was found between HRV during MDCT scanning and the mean image quality for all coronary segments (r=0.47, p<0.01). There was an association between HRV and state anxiety scores in all cases (r=0.370, p<0.01). HRV in the patients who received alprazolam was statistically significantly lower than in controls (p<0.05). The average image quality in patients who used alprazolam was also statistically significantly higher than in controls (p<0.05).ConclusionsThe most important finding in our study is that oral premedication to reduce anxiety is also effective in decreasing HRV and improves image quality. Therefore, we suggest that using alprazolam in addition to a β-blocker may improve image quality in patients undergoing MDCT coronary angiography (MDCT-CA). Anxiolytic usage may improve image quality by lowering the HRV in selected cases where administration of a β-blocker is contraindicated. We also suggest that further studies in larger series are required to validate this finding.RiassuntoObiettivoValutare la relazione tra la qualità delle immagini in TC multidetettore a 64 strati (MDCT), lo stato d’ansia dei pazienti prima dell’esame TC e la variabilità della frequenza cardiaca (HRV); valutare l’efficacia della somministrazione per via orale di ansiolitici sulla variabilità della frequenza cardiaca (HRV) e sulla qualità delle immagini.Materiali e metodiSono stati studiati 60 pazienti [14 donne, 46 uomini;età media 52,53±10,55 (DS), intervallo 33–78 anni]. Il livello d’ansia è stato stimato a monte della procedura con l’ausilio della forma Y dello State-Trait Anxiety Inventory 60 (STAI-Y). I pazienti che hanno partecipato allo studio sono stati casualmente assegnati ad uno dei due gruppi di studio: il gruppo di controllo (ai quali non veniva somministrato ansiolitico per ridurre lo stato d’ansia) ed il gruppo dei pazienti trattati con ansiolitici, quest’ultimo composto da 30 pazienti. La presenza di artefatti da movimento e la qualità delle immagini per ciascun segmento coronarico studiato, sono state valutate utilizzando un sistema di classificazione a 4 punti. La stima della variabilità della frequenza cardiaca (HRV) e la durata di ciascun battito cardiaco durante l’acquisizione dei dati in MDCT sono stati misurati in ogni paziente.RisultatiÈ stata riscontrata una moderata correlazione tra la variabilità della frequenza cardiaca (HRV) durante l’acquisizione delle immagini MDCT e la media della qualità dell’immagine per tutti i segmenti coronarici studiati (r=0,47, p<0,01). Vi era una concordanza tra la variabilità della frequenza cardiaca (HRV) ed il livello d’ansia in tutti i casi (r=0,370, p<0,01). La variabilità della frequenza cardiaca (HRV) nei pazienti trattati con alprazolam era significativamente più bassa che nei controlli (p<0,05). Anche la qualità delle immagini nei pazienti trattati con alprazolam era significativamente più elevata che nei controlli (p<0,05).ConclusioniIl riscontro del nostro studio è che la premedicazione con ansiolitici per via orale riduce lo stato d’ansia ed è efficace anche nel ridurre la variabilità della frequenza cardiaca (HRV) e nel migliorare la qualità delle immagini. Pertanto, suggeriamo che l’utilizzo dell’alprazolam in combinazione con gli β-litici potrebbe migliorare la qualità delle immagini nei pazienti sottoposti ad angiografia coronarica mediante TC multidetettore (MDCT-CA). L’utilizzo degli ansiolitici potrebbe migliorare la qualità delle immagini diminuendo la variabilità della frequenza cardiaca (HRV) in casi selezionati dove è controindicata la somministrazione degli β-litici. Per poter validare questi risultati sono necessari ulteriori studi su casistiche più ampie.