Rizal Damanik

Anti-bacterial and anti-fungal activity of coleus leaves consumed as breast-milk stimulant

Purpose – The aim of this study was to evaluate anti-bacterial anti-fungal activity of six Lamiaceae family coleus plants based on their traditional uses (breast-milk stimulants) from two Asian countries (Malaysia and Indonesia). Design/methodology/approach – Plants leaves of coleus species were collected from Kuantan (Malaysia) and Jakarta (Indonesia). From Kuantan, Coleus aromaticus – Malaysia (CATM), Pogostemon cablin – Malaysia (PCM), Coleus blumei-purple leaves – Malaysia (CBPM), Coleus blumei-red leaves – Malaysia (CBRM), Coleus amboinicus – Malaysia (CALM) and from Jakarta Coleus amboinicus – Indonesia (CALI) were collected freeze dried and extracted with aqueous methanol. The antimicrobial activity of the extract was determined by making use of macro dilution and disc diffusion methods. The selected bacteria and fungus used were namely Bacillus subtilis and Staphylococcus aureus (gram positive) and Escherichia coli and Pseudomonas aeruginosa (gram negative) and Candida albicans (a fungi). Findings...

Torbangun (Coleus amboinicus Lour) Extracts Affect Microbial and Fungus Activities

Coleus also known as Torbangun or Ati Ati plants leaves i.e. Coleusamboinicus Lour from Indonesia (CAL-I) and Coleus aromaticus (CAT-M), Pogostemon cablin (PC-M), Coleus blumei –red leaves (CBR-M), Coleus amboinicus – (CAL-M) Coleus blumei –purple leaves (CBP-M) from Malaysia were collected, freeze dried and extracted with aqueous methanol. The effect of the extract was assessed on microbial and fungal activities in relation to their phytochemicals and antioxidants concentrations. The total phenolic content was determined according to the Folin-Ciocalteu method whilst antioxidant activity was assessed using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) method. The anti-microbial and anti-fungal activities were assessed by minimum inhibitory concentrations (MIC) and disc diffusion methods. The result indicates that the extracts are rich sources of phytochemicals and antioxidants from the listed plants. When the effect of the extracts was assessed on microbial and fungal activities it was observed that the effect was more pronounced on the gram-positive bacteria compared to gram-negative bacteria. Furthermore, there was strong association between phytochemicals and antioxidants concentration and with the microbial and fungal activities. However, it was not consistent for all types of strains. This study shows that Torbangun plants extracts are rich in phenolic contents therefore; it can be used as free radical scavengers and antimicrobial agent apart from other traditional uses

PERTUMBUHAN BAYI DAN PEMBERIAN ASI EKSKLUSIF OLEH IBU PENERIMA KONSELING MENYUSUI DAN MAKANAN TAMBAHAN TORBANGUN

The objective of this study was to assess the micronutrient and nutritional status among female adolescents having low birth weight history and normal birth weight history. Research design for this particular research was nested cohort in community level. Subjects was chosen by simple randomization, based on data collected by Frontiers for Health Foundation and Padjajaran University, Bandung. The measurement of micronutrients status (Hb, retinol plasma, and urinary iodine excretion), anthropometric, history of disease, semi quantitative food frequency questionnaire was collected to make comparison between female young adolescent with low birth weight and normal birth weight history. The prevalence of iron deficiency anemia (IDA), vitamin A deficiency (VAD), and iodine deficiency among all subjects were 9.9%, 12.9%, and 40.7%, respectively. The mean concentration of blood hemoglobin, plasma retinol and iodine excretion were not significantly different between low birth weight (LBW) and normal birth weight (NBW) group. Nutritional status, disease during the last three months, current nutritional status, food intake and onset of menstruation were not significantly different between group. In conclusion, micronutrient status, nutritional status, food intake and morbidity status in female adolescents with LBW and NBW history were not different.