Robert J. Rafka | Researchain

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Featured researches published by Robert J. Rafka.

Bioorganic & Medicinal Chemistry Letters | 2006

5-Heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part 1: Structure-activity relationship studies of 5-alkylamino pyrazoles and discovery of a potent, selective, and orally active analog

Subas M. Sakya; Kristin Lundy DeMello; Martha L. Minich; Bryson Rast; Andrei Shavnya; Robert J. Rafka; David A. Koss; Hengmiao Cheng; Jin Li; Burton H. Jaynes; Carl Bernard Ziegler; Donald W. Mann; Carol F. Petras; Scott B. Seibel; Annette M. Silvia; David M. George; Lisa A. Lund; Suzanne H. St. Denis; Anne Hickman; Michelle L. Haven; Michael P. Lynch

Organic Letters | 2011

Mild decarboxylative activation of malonic acid derivatives by 1,1'-carbonyldiimidazole.

Danny Lafrance; Paul Bowles; Kyle R. Leeman; Robert J. Rafka

Journal of Agricultural and Food Chemistry | 2004

An Analytical Method for the Analysis of Tulathromycin, an Equilibrating Triamilide, in Bovine and Porcine Plasma and Lung

Diana Galer; Scott Hessong; Brian Beato; James Risk; Philip B. Inskeep; Chandralal A. Weerasinghe; Richard P. Schneider; Connie Langer; Jennifer Laperle; Donald Renouf; Andrew J. Bessire; Eden Espanol; Robert J. Rafka; Colman Brendan Ragan; Wayne Boettner; Trisha Murphy; David Keller; Hafid Benchaoui; Marcus A. Nowakowski

Bioorganic & Medicinal Chemistry Letters | 2006

Synthesis and SAR of heteroaryl-phenyl-substituted pyrazole derivatives as highly selective and potent canine COX-2 inhibitors.

Hengmiao Cheng; Kristin Lundy DeMello; Jin Li; Subas M. Sakya; Kazuo Ando; Kiyoshi Kawamura; Tomoki Kato; Robert J. Rafka; Burton H. Jaynes; Carl Bernard Ziegler; Rod Stevens; Lisa A. Lund; Donald W. Mann; Carolyn Rose Kilroy; Michelle L. Haven; Erik L. Nimz; Jason K. Dutra; Chao Li; Martha L. Minich; Nicole L. Kolosko; Carol F. Petras; Annette M. Silvia; Scott B. Seibel

Bioorganic & Medicinal Chemistry Letters | 2004

Discovery of a potent, selective and orally active canine COX-2 inhibitor, 2-(3-difluoromethyl-5-phenyl-pyrazol-1-yl)-5-methanesulfonyl-pyridine.

Jin Li; Kristin Lundy DeMello; Henry Cheng; Subas M. Sakya; Brian Scott Bronk; Robert J. Rafka; Burton H. Jaynes; Carl Bernard Ziegler; Carolyn Rose Kilroy; Donald W. Mann; Eric L. Nimz; Michael P. Lynch; Michelle L. Haven; Nicole L. Kolosko; Martha L. Minich; Chao Li; Jason K. Dutra; Bryson Rast; Rhonda Marie Crosson; Barry James Morton; Glen W. Kirk; Kathleen M. Callaghan; David A. Koss; Andrei Shavnya; Lisa A. Lund; Scott B. Seibel; Carol F. Petras; Annette M. Silvia

Archive | 1999

13-membered azalides and their use as antibiotic agents

Robert J. Rafka; Barry James Morton; Colman Brendan Ragan; Peter Bertinato; John P. Dirlam; Alan Elwood Blize; Carl Bernard Ziegler

Bioorganic & Medicinal Chemistry Letters | 2006

5-Heteroatom-substituted pyrazoles as canine COX-2 inhibitors: Part 2. Structure–activity relationship studies of 5-alkylethers and 5-thioethers

Subas M. Sakya; Hengmiao Cheng; Kristin Lundy DeMello; Andrei Shavnya; Martha L. Minich; Bryson Rast; Jason K. Dutra; Chao Li; Robert J. Rafka; David A. Koss; Jin Li; Burton H. Jaynes; Carl Bernard Ziegler; Donald W. Mann; Carol F. Petras; Scott B. Seibel; Annette M. Silvia; David M. George; Anne Hickman; Michelle L. Haven; Michael P. Lynch

Bioorganic & Medicinal Chemistry | 2005

In vitro and in vivo profile of 2-(3-di-fluoromethyl-5-phenylpyrazol-1-yl)-5-methanesulfonylpyridine, a potent, selective, and orally active canine COX-2 inhibitor

Jin Li; Michael P. Lynch; Kristin Lundy DeMello; Subas M. Sakya; Hengmiao Cheng; Robert J. Rafka; Brian Scott Bronk; Burton H. Jaynes; Carolyn Rose Kilroy; Donald W. Mann; Michelle L. Haven; Nicole L. Kolosko; Carol F. Petras; Scott B. Seibel; Lisa A. Lund

Archive | 2000