Sabyasachi Banerjee

Disseminated cutaneous histoplasmosis, an initial manifestation of hiv, diagnosed with fine needle aspiration cytology

Acute progressive disseminated histoplasmosis (PDH) may be the initial manifestation of human immunodeficiency virus (HIV). However, cutaneous involvement is very rare. We present an unusual case of acute PDH with multiple diffuse cutaneous papulonodular lesions predominantly on the face, trunk, and upper extremities, diagnosed initially with fine needle aspiration cytology (FNAC). Subsequent serological tests revealed positivity for antibodies for HIV 1 and 2. The cytomorphological features were further confirmed by biopsy and histochemical stains. FNAC is a rapid, cost-effective tool that may be utilized in the diagnosis of papulonodular forms of PDH and for initiating prompt therapy. We discuss the clinical features, clinical differentials, and treatment of the condition.

Familial leiomyomatosis cutis affecting nine family members in two successive generations including four cases of Reed's syndrome.

Reeds syndrome or familial leiomyomatosis cutis et uteri is an autosomal dominant disorder, characterized by multiple cutaneous and uterine leiomyomas. We report here a case of a 53-year-old woman who presented to us with multiple painful nodules over different parts of her body. Based on the histopathological examination, imaging, and past medical records, a diagnosis of Reeds syndrome was made. Three of her sisters had similar disease. Subsequently, it was found that a total of nine members of their family in two successive generations were affected with cutaneous leiomyomas. The present case series has been reported for its interesting clinical presentations and rarity.

Skin diseases in HIV-infected patients: Impact of immune status and histological correlation.

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Non healing solitary noduloulcerative growth over axilla.

Sir, Basal cell carcinoma (BCC) usually presents on face and other sun exposed parts. Uncommonly, BCC may develop over atypical locations like axilla, nipple, scrotum, pubis, and perianal region posing a diagnostic challenge then. Very few cases of Axillary BCC have been documented in literature and only two cases have been reported from Asia.[1] Here we report a case of axillary BCC due to its extreme rarity and uncommon clinical presentation posing difficulty in diagnosis.