Satomi Hattori

Successful treatment of Kimura's disease with cyclosporine

We report the case of a 29-year-old Japanese woman presenting with recurring Kimuras disease. We began treatment with cyclosporine within 7 days, the nodular lesion had almost cleared. The cyclosporine dose was then gradually reduced and discontinued after 6 months. The patient was reassessed 18 months after the cessation of treatment and there was no evidence of recurrence of the disease. We speculate that the effects of cyclosporine on T helper-2 cells improves Kimuras disease.

A case of renal cancer discovered by multiple skin transition.

A 74-year-old female with skin metastasis of renal cell carcinoma is described.She noticed her cutaneous lesion on her left lower abdomen about three years before visiting our dermatological outpatient clinic. The lesion gradually enlarged and multiple nodule developed on the other parts of the body.The biopsy was taken from the lesion on the right arm. On microscopic findings, the metastasis of renal cell carcinoma was suggested. An examination of whole body was performed and renal cell carcinoma of left kidney was discovered. Systemic and multi-organ involvement were also observed.This case is rare because the patient had a large number of metastatic skin lesions up to 62. In addition, she lived at least 3 years after the metastasis of the skin. It is relatively a long period for the patient with metastatic renal cell carcinoma.