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Dive into the research topics where Jun Yajima is active.

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Featured researches published by Jun Yajima.


Contact Dermatitis | 1997

Allergic contact dermatitis from curcumin (turmeric)

Mieko Hata; Eiko Sasaki; Makoto Ota; Kazuhisa Fujimoto; Jun Yajima; Toshihiko Shichida; Mitsuyoshi Honda

Discussion Neticonazole, a vinyl imidazole derivative (Fig. 2), is a newly developed antifungal drug in use since 1995. Contact allergy due to neticonazole has not been reported in the literature. Another vinyl imidazole, croconazole, has caused contact sensitivity (I). Cross-sensitization between 2-(2,4-dichlorophenyl)-ethyl imidazoles, e.g. econazole, isoconazole, miconazole, oxiconazole, and sulconazole, is well-known (2-5). Our case cross-reacted to econazole and sulconazole, but not to croconazole, suggesting that the vinyl base may not be related to the antigenic determinant. Non-imidazole drugs (morpholine, benzylamine, or allylamine) should be prescribed in these patients.


Skin Cancer | 1994

A case of renal cancer discovered by multiple skin transition.

Yumiko Tamiya; Makoto Ota; Yayoi Niimi; Mikako Aoki; Mieko Hata; Jun Yajima; Satomi Hattori; Mitsuyoshi Honda; Haruo Kaneko; Koichi Hayakawa; Tetsuo Maruta; Zenya Naito; Goro Asano

A 74-year-old female with skin metastasis of renal cell carcinoma is described.She noticed her cutaneous lesion on her left lower abdomen about three years before visiting our dermatological outpatient clinic. The lesion gradually enlarged and multiple nodule developed on the other parts of the body.The biopsy was taken from the lesion on the right arm. On microscopic findings, the metastasis of renal cell carcinoma was suggested. An examination of whole body was performed and renal cell carcinoma of left kidney was discovered. Systemic and multi-organ involvement were also observed.This case is rare because the patient had a large number of metastatic skin lesions up to 62. In addition, she lived at least 3 years after the metastasis of the skin. It is relatively a long period for the patient with metastatic renal cell carcinoma.


Skin Cancer | 1993

Example of Bowen disease from porokeratosis.

Touichi Kitahara; Kaoruko Nakajoh; Yumiko Tamiya; Yayoi Niimi; Mikako Aoki; Jun Yajima; Mitsuyoshi Honda; Hiko Hyakusoku; Mamoru Morioka

We reported on one case of Bowens disease believed to have arisen from porokeratosis. It is known that malignant tumors develop from the porokeratosis eruption, so the course of the disease has to be monitored over a period of time. Further, acutive histological examination should be carried out with this disease when the following are recognized in the area of the eruption, erythema, roughening of the surface, warts, erosion, ulcers, or the adherence of a crust.


Skin Cancer | 1993

A case of head apocrine adenocarcinoma.

Mikako Aoki; Makoto Ota; Yayoi Niimi; Jun Yajima; Mitsuyoshi Honda; Hiko Hyakusoku; Yuh Fukuda; Hiroshi Saito

A case of apocrine adenocarcinoma arising in the scalp is reported. A 69-year-old male presented with an ulcerated nodular reddish firm mass in his scalp and two subcutaneous nodules in the left side of his neck. The biopsy suggested a metastatic adenocarcinoma, but a whole body CT, Ga scintigram and other examinations revealed no evidence of malignant tumor in other organs. Therefore we diagnosed it as sweat gland carcinoma and the wide resection and total neck dissection were done. The histopathology of the resected tumor showed adenocarcinoma with varying degrees of differentiation, composed of cords and nests which occasionally formed branching lumina. Atypical epithelial cells had abundant eosinophilic cytoplasm and only rarely showed projections from the apical cytoplasm consistent with decapitation secretion. Some tumor cells and luminal eosinophilic material were PAS positive, diastase-resistant, and were also alcian blue and CEA positive. By electron microscopy, the epithelial cells showed enlarge and rounded mitochondria and electron dense secretory granules, but no tonofilaments in the cytoplasm. Microvilli were seen along the luminal membrane. Infrequently apical membranes protruded in the lumen and showed typical dividing membrane. In addition, myoepithelial cells were seen along the basal epithelial membranes that led us to the final diagnosis of apocrine adenocar-cinoma.It is difficult to make a diagnosis of carcinoma of sweat glands, especially in poorly differentiated cases, because of the histological similarity to metastatic adenocarcinoma in the skin. Apocrine adenocarcinoma that usually occurs in axilla or wherever apocrine glands normally exist and has high risk of regional lymph nodes metastasis is an uncommon neoplasm. Our case of apocrine adenocarcinoma of the scalp is the 4th reported case in Japan. Immuno-histochemical stainings are likely to be overused to make a diagnosis of sweat gland carcinoma. We should be reminded that some basic histological features such as decapitation secretion or myoepithelial cells which are elongated cells surrounding tumor nests and positive for smoothmuscle actin are still very contributory to define these tumors.Mishima and Morioka suggest sweat gland tumors can be classified according to their anatomical origin and malignancy that provide us relatively clear-cut concept of these tumors. Using Mishima and Morioka system, we classify this tumor as an apocrine spirocarinoma because of the presence of decapitation secretion and myoepithelial cells, and the absence of tonofilaments.


Contact Dermatitis | 1988

Contact dermatitis due to amcinonide

Eiko Sasaki; Mariko Shinya; Michi Fujioka; Motoyasu Sato; Mieko Hata; Jun Yajima; Satomi Hattori; Mitsuyoshi Honda


Contact Dermatitis | 2002

Allergic contact dermatitis due to hydrophilized ceramide

Jun Yajima


Contact Dermatitis | 1997

Allergic contact dermatitis from amorolfine cream

Katsumi Kaneko; Nujaji Aoki; Mieko Hata; Jun Yajima; Seiji Kawana; Satinu Hattori


Skin Cancer | 1996

A case of Meibomian gland cancer.

Amiko Hashimoto; Mikako Aoki; Mieko Hata; Jun Yajima; Mitsuyoshi Honda; Kiyoshi Mitsuhashi; Hiko Hyakusoku; Miyoko Kumakawa; Shigeaki Nakayama; Sanae Shimada; Shotaro Maeda


日本小児皮膚科学会雑誌 = Journal of pediatric dermatology | 1999

Lupus Miliaris Disseminatus Faciei in Children

Yoko Iwasaki; Mieko Hata; Takako Sakakibara; Junko Aoki; Kazuhisa Fujimoto; Jun Yajima; Mitsuyoshi Honda; Seiji Kawana; Eiko Sasaki


日本小児皮膚科学会雑誌 = Journal of pediatric dermatology | 1996

Contact Dermatitis in Children : Recent Topics

Jun Yajima; Mitsuyoshi Honda

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