Satya P. Popli

Monoterpenoid furanocoumarin lactones from clausena anisata

Abstract A reinvestigation of Clausena anisata has yielded imperatorin, xanthotoxol, lansamide-I and three new furanocoumarin lactone derivatives: indicolactone, anisolactone and 2′,3′-epoxyanisolactone. The structures of these compounds have been elucidated by a combination of spectroscopic and chemical methods.

New alkaloids from Tabernaemontana divaricata

Abstract A re-investigation of the root bark of Tabernaemontana divaricata resulted in the isolation of 18 compounds, viz. α-amyrin acetate, lupeol acetate, α-amyrin, lupeol, cycloartenol, β-sitosterol, campesterol, benzoic acid, aurantiamide acetate, coronaridine, coronaridine hydroxyindolenine ( 1 ), ibogamine, 5-hydroxy-6-oxocoronaridine ( 6 ), 5-oxocoronaridine ( 9 ), 6-oxocoronaridine ( 10 ), (±)-19-hydroxycoronaridine ( 11 ), 3-oxocoronaridine ( 12 ) and voacamine. The alkaloids 6 , 9 , 10 and 11 are new compounds, whereas cycloartenol, campesterol, ibogamine, benzoic acid, aurantiamide acetate and coronaridine hydroxyindolenine are reported from this plant for the first time.

Toddasin, a new dimeric coumarin from Toddalia asiatica.

Abstract A new dimeric coumarin, named toddasin and possessing a cyclohexene ring with a vinylic side-chain interposed between the two coumarin moieties has been isolated from the roots of Toddalia asiatica. It has been characterized as (E)-8,8′-[1″,4″-dimethyl-3″ -cyclohexen-1″,2″-ylene vinylene]-bis-[5,7-dimethoxycoumarin] (1). The proposed structure is supported by the mass fragmentation of its dihydro derivative (2).

A furanoeremophilane from Vitex negundo

Abstract Acetyl oleanolic acid, sitosterol and a new furanoeremophilane characterized as 3-formyl-4,5-dimethyl-8-oxo-5 H -6,7-dihydronaphtho(2,3- b )furan have been isolated from the roots of Vitex negundo .

8-hydroxydihydrochelerythrine and arnottianamide from roots of Toddalia asiatica☆

Abstract In addition to hexacosanoic acid, β-sitosterol and arnottianamide, 8-hydroxydihydrochelerythrine, a new benzophenanthridine alkaloid has been isolate

Toddanol and toddanone, two coumarins from Toddalia asiatica

Abstract Two new constituents isolated from the roots of Toddalia asiatica and designated as toddanol and toddanone have been characterized as 5,7-dimethoxy-6-(2-hydroxy-3-methylbut-3-enyl)coumarin ( 1 ) and 5,7-dimethoxy-6-(3-methyl-2-oxobutanyl)coumarin ( 3 ), respectively, by spectral analysis and interconversion experiments.

Two diuretic triterpenoids from Antidesma menasu

Abstract Two new pentacyclic triterpenoids characterized as 16α-hydroxy-3-ketoisomultiflorene and 3β-hydroxy-16-ketoisomultiflorene have been isolated from the aerial parts of Antidesma menasu. Both of these compounds displayed diuretic activity in experimental animals.

Studies in medicinal plants. Part III. Protoberberine alkaloids from the roots ofCissampelos pareira linn

Cissaminechlorid aus den Wurzeln vonCissampelos pareira Linn. ist als Protoberberin-Alkaloid erkannt und mit Cyclanolinechlorid ausStephania terandra identifiziert worden.

Synthesis of (±)-isomedicarpin, (±)-homopterocarpin and tuberostan: a novel entry of ‘hydrogenative cyclisation’ into pterocarpans

An efficient three-step synthesis of the coumestan, tuberostan (1), from the benzyloxyisoflavone (2) is described. The synthesis involves a single-step ‘hydrogenative cyclisation’ of the isoflavone (2) to the pterocarpan, (±)-isomedicarpin (5)

New alkaloids from Aegle marmelos

Abstract Four new alkaloids, O -(3,3-dimethylallyl)-halfordinol, N -2-ethoxy-2-(4-methoxyphenyl)ethylcinnamamide, N -2-methoxy-2-[4-(3′,3′-dimethyl