Aboo Shoeb

Bacteriostatic heterocycles from Euodia lunu-ankenda☆

Abstract A new constituent characterized as 8-acetyl-3,4-dihydroxy-5,7-dimethoxy-2,2-dimethylchroman has been isolated together with alloevodionol-7-methyl ether, 4-methoxy-1-methyl-2(1H)quinolinone, evolitrine, isoevodionol and its methyl ether from the aerial parts of Euodia lunu-ankenda. Its structure was confirmed by its transformation to alloevodionol-7-methyl ether. 4-Methoxy-1-methyl-2(1H)quinolinone and its isomer were synthesized by a modified procedure.

Toddasin, a new dimeric coumarin from Toddalia asiatica.

Abstract A new dimeric coumarin, named toddasin and possessing a cyclohexene ring with a vinylic side-chain interposed between the two coumarin moieties has been isolated from the roots of Toddalia asiatica. It has been characterized as (E)-8,8′-[1″,4″-dimethyl-3″ -cyclohexen-1″,2″-ylene vinylene]-bis-[5,7-dimethoxycoumarin] (1). The proposed structure is supported by the mass fragmentation of its dihydro derivative (2).

A lignan from Lonicera hypoleuca

Abstract A new lignan characterised as (-)-4-hydroxy-2,6-di-(4′-hydroxy-3′-methoxy)phenyl-3,7-dioxabicyclo-(3.3.0)octane along with n -10-nonacosanol, scopoletin, syringic acid, β-sitosterol and its glucoside, has been isolated from the aerial parts of Lonicera hypoleuca . The stereochemistry of the lignan has been established by its spectroscopic analysis and those of its derivatives, and by its conversion to (+)-pinoresinol. β-Sitosterol-β- D -glucoside displayed good spasmolytic activity.

A furanoeremophilane from Vitex negundo

Abstract Acetyl oleanolic acid, sitosterol and a new furanoeremophilane characterized as 3-formyl-4,5-dimethyl-8-oxo-5 H -6,7-dihydronaphtho(2,3- b )furan have been isolated from the roots of Vitex negundo .

8-hydroxydihydrochelerythrine and arnottianamide from roots of Toddalia asiatica☆

Abstract In addition to hexacosanoic acid, β-sitosterol and arnottianamide, 8-hydroxydihydrochelerythrine, a new benzophenanthridine alkaloid has been isolate

Toddanol and toddanone, two coumarins from Toddalia asiatica

Abstract Two new constituents isolated from the roots of Toddalia asiatica and designated as toddanol and toddanone have been characterized as 5,7-dimethoxy-6-(2-hydroxy-3-methylbut-3-enyl)coumarin ( 1 ) and 5,7-dimethoxy-6-(3-methyl-2-oxobutanyl)coumarin ( 3 ), respectively, by spectral analysis and interconversion experiments.

Two diuretic triterpenoids from Antidesma menasu

Abstract Two new pentacyclic triterpenoids characterized as 16α-hydroxy-3-ketoisomultiflorene and 3β-hydroxy-16-ketoisomultiflorene have been isolated from the aerial parts of Antidesma menasu. Both of these compounds displayed diuretic activity in experimental animals.

New alkaloids from Aegle marmelos

Abstract Four new alkaloids, O -(3,3-dimethylallyl)-halfordinol, N -2-ethoxy-2-(4-methoxyphenyl)ethylcinnamamide, N -2-methoxy-2-[4-(3′,3′-dimethyl

Synthesis of sulphur heterocycles as hepatoprotectants : part I

Abstract The synthesis and hepatoprotective activity of 1,3-dithiolanes(2), 1,3-dithianes(3), 2H-thiopyran-2-thione(4), 1,3-dithiole-2-thione(5) and pyrazole(6) are described.

Isoquinoline derived alkaloids from Berberis chitria

Abstract A new aporphine base characterized as O-methylcorydine-N-oxide together with berberine, palmatine, jatrorrhizine and oxyacanthine has been isolated from Berberis chitria.