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Dive into the research topics where Shelly N. Binkley is active.

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Featured researches published by Shelly N. Binkley.


Drug Metabolism and Disposition | 1995

Comparisons of phase I and phase II in vitro hepatic enzyme activities of human, dog, rhesus monkey, and cynomolgus monkey.

J E Sharer; Lisa A. Shipley; Mark Vandenbranden; Shelly N. Binkley; Steven A. Wrighton


Journal of Pharmacology and Experimental Therapeutics | 1999

Three- and Four-Dimensional Quantitative Structure Activity Relationship Analyses of Cytochrome P-450 3A4 Inhibitors

Sean Ekins; Shelly N. Binkley; Jennifer S. Gillespie; Barbara J. Ring; James H. Wikel; Steven A. Wrighton


British Journal of Clinical Pharmacology | 1996

In vitro interaction of the antipsychotic agent olanzapine with human cytochromes P450 CYP2C9, CYP2C19, CYP2D6 and CYP3A

Barbara J. Ring; Shelly N. Binkley; Mark Vandenbranden; Steven A. Wrighton


Pharmacogenetics | 1996

Interaction of human liver cytochromes P450 in vitro with Ly307640, a gastric proton pump inhibitor

Mark Vandenbranden; Barbara J. Ring; Shelly N. Binkley; Steven A. Wrighton


Drug Metabolism and Disposition | 2000

Three- and Four-Dimensional-Quantitative Structure Activity Relationship (3D/4D-QSAR) Analyses of CYP2C9 Inhibitors

Sean Ekins; Shelly N. Binkley; Jennifer S. Gillespie; Barbara J. Ring; James H. Wikel; Steven A. Wrighton


Pharmacogenetics | 1999

Three and four dimensional-quantitative structure activity relationship (3D/4D-QSAR) analyses of CYP2D6 inhibitors.

Sean Ekins; Shelly N. Binkley; Jennifer S. Gillespie; Barbara J. Ring; James H. Wikel; Steven A. Wrighton


International Journal of Clinical Pharmacology and Therapeutics | 1998

Autoactivation and activation of the cytochrome P450s.

Sean Ekins; Barbara J. Ring; Shelly N. Binkley; Stephen D. Hall; Steven A. Wrighton


Journal of Pharmacology and Experimental Therapeutics | 2001

Identification of the Human Cytochromes P450 Responsible for in Vitro Formation of R- and S-Norfluoxetine

Barbara J. Ring; James A. Eckstein; Jennifer S. Gillespie; Shelly N. Binkley; Mark Vandenbranden; Steven A. Wrighton


Journal of Pharmacology and Experimental Therapeutics | 1995

Effect of fluoxetine, norfluoxetine, sertraline and desmethyl sertraline on human CYP3A catalyzed 1'-hydroxy midazolam formation in vitro.

Barbara J. Ring; Shelly N. Binkley; L Roskos; Steven A. Wrighton


Drug Metabolism and Disposition | 1998

Alterations of the catalytic activities of drug-metabolizing enzymes in cultures of human liver slices

Mark Vandenbranden; Steven A. Wrighton; Sean Ekins; Jennifer S. Gillespie; Shelly N. Binkley; Barbara J. Ring; Gadberry Mg; Mullins Dc; Stephen C. Strom; Jensen Cb

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Mark Vandenbranden

Medical College of Wisconsin

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