Shigeo Eda

Calcifying odontogenic cyst: Report of a case

Abstract 1. 1. A case of calcifying odontogenic cyst, formed between the canine and the first premolar on the left upper jaw, was studied. 2. 2. There was no impacted tooth in the locality. 3. 3. It was proved that the ghost cells contain SS groups in proteins and are keratinized. 4. 4. The calcified substance in the cyst contained neutral and acid mucopolysaccharides.

Ultrastructural study of initial calcification in the rat subcutaneous tissues elicited by a root canal filling material

The ultrastructural aspects of initial calcification in the rat subcutaneous tissues elicited by the root canal filling material Vitapex, made up of calcium hydroxide and iodoform with the addition of silicone oil, were studied by means of electron microscopic and cytochemical techniques. The embedded paste caused heterotopic calcifications. These were divided into two types: dystrophic calcification and matrix vesicle calcification which resembled that of bone tissue. These data suggest that Vitapex may be an excellent root canal filling material for differentiation of osteoblasts or cementoblasts from mesenchymal cells in the periodontal ligament.

Evaluation of heterotopic bone formation induced by squalane and bone morphogenetic protein composite

Bone morphogenetic protein is an important molecule whose bioactivity depends on the carrier. Squalane is used in the formulation of various kinds of cosmetics because it is easily emulsified and has the property of spreading well. Thus, squalane might be effective as a bone morphogenetic protein delivery system. As a test for this possibility, gelatin capsules containing squalane and bone morphogenetic protein (bovine derived partially purified) composite were implanted under the hindquarter perimuscular membrane of ddY mice. Control capsules containing only bone morphogenetic protein were used for controls. The implants were radiographically and histologically examined at 1 to 4 weeks after the operation. According to the radiographic analysis, squalane and bone morphogenetic protein composite and bone morphogenetic protein only control specimens formed widespread heterotopic bone tissues. The amount of heterotopic bone formation in the composite experimental specimens was approximately 40% greater than that in the controls. Histologic examination of experimental and control specimens revealed varying amounts of perichondral ossification by 2 weeks. By 3 and 4 weeks, the bone deposits were colonized by hematopoietic bone marrow. Squalane was effective for the slow local release of bone morphogenetic protein. Furthermore, the squalane and bone morphogenetic protein composite was a reliable osteoinductive biomaterial.

An experimental study of intraoral carcinogenesis in rats

A new method has been devised for preparing artificial cecal pouches lined with mucous epithelium in the lower lips of Wistar and Sprague-Dawley rats in order to make carcinogens act continuously for a long time in the oral mucosa. When a 0.5 per cent mineral oil solution of DMBA, a crystal of MC, and a crystal of NG were administered, squamous-cell carcinoma, carcinoma in situ, papilloma, adenoma sebaceum. neurofibroma, fibroma, hemangiosarcoma, hemangiosarcoma, hemangioma, and lymphangioma were successfully produced in the oral mucosa of rats. In addition, interesting findings were obtained concerning tissue changes in the process of carcinogensis in the mucous epithelium.

A rare variant of acinic cell carcinoma of the upper lip: A case report and review of the literature

Acinic cell carcinomas of the lip are most uncommon. An exhaustive search of the Japanese- and English-language literature has revealed only 17 previously reported cases. One additional occurrence, a rare variant of this type of neoplasm, with mucous differentiation, that occurred in the upper lip of a 60-year-old man is described here. A brief review of the literature on this type of lip tumor is also given.

Hyperkeratosis and atypical proliferation appearing in the lining epithelium of a radicular cyst. Report of a case

It is widely accepted that radicular cysts (apical periodontal cysts) are commonly lined with stratified squamous epithelium without keratin formation. However, we identified a case of maxillary radicular cyst with remarkable keratinization and atypical proliferation of the lining epithelium among the 207 radicular cyst cases seen at our department. Histopathological and clinical findings of these cysts were reviewed.

Procion Navy Blue in pulp and periapical studies

Abstract In an investigation of its value as a pulp-preserving medium, Procion Navy Blue was applied to the pulps of monkey teeth which had been exposed by an air-turbine drill. Evaluation of block sections of teeth and surrounding bone revealed that in all cases there was a severe inflammatory reaction in the pulp, which increased in severity with increases in observation time. Thus, Procion Navy Blue is not considered suitable for the treatment of exposed pulps.