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Steven van Zutphen

Leiden University

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Publication

Featured researches published by Steven van Zutphen.

Chemical Communications | 2003

Extending solid-phase methods in inorganic synthesis: the first dinuclear platinum complex synthesised via the solid phaseElectronic supplementary information (ESI) available: Definitions for abbreviations used, and synthesis of 1a, 1b, 4 and 7. See http://www.rsc.org/suppdata/cc/b2/b212388f/

Steven van Zutphen; Marc S. Robillard; Gijs A. van der Marel; Herman S. Overkleeft; Hans den Dulk; Jaap Brouwer; Jan Reedijk

A method for obtaining potentially anti-tumour active dinuclear platinum coordination compounds via solid-phase inorganic synthesis is described for the first time.

Coordination Chemistry Reviews | 2005

Targeting platinum anti-tumour drugs : Overview of strategies employed to reduce systemic toxicity

Steven van Zutphen; Jan Reedijk

Organometallics | 2007

Xanthene-Phosphole Ligands: Synthesis, Coordination Chemistry, and Activity in the Palladium-Catalyzed Amine Allylation

Guilhem Mora; Bernard Deschamps; Steven van Zutphen; Xavier F. Le Goff; Louis Ricard; Pascal Le Floch

Organometallics | 2009

INDOLPhosphole and INDOLPhos palladium-allyl complexes in asymmetric allylic alkylations

Jeroen Wassenaar; Steven van Zutphen; Guilhem Mora; Pascal Le Floch; Maxime A. Siegler; Anthony L. Spek; Joost N. H. Reek

Journal of Inorganic Biochemistry | 2006

Three new asymmetric trans-amine(azole)dichloridoplatinum complexes that overcome cisplatin resistance and their reactions with 5'-GMP.

Elena Pantoja; Agata Gallipoli; Steven van Zutphen; Seiji Komeda; Desigan Reddy; Deogratius Jaganyi; Martin Lutz; Duncan M. Tooke; Anthony L. Spek; Carmen Navarro-Ranninger; Jan Reedijk

Journal of Inorganic Biochemistry | 2004

Water-soluble platinum(II) complexes of diamine chelating ligands bearing amino-acid type substituents: the effect of the linked amino acid and the diamine chelate ring size on antitumor activity, and interactions with 5'-GMP and DNA.

Silvia Moradell; Julia Lorenzo; Ana Rovira; Steven van Zutphen; Francesc X. Avilés; Virtudes Moreno; Rafael de Llorens; M.Angeles Martinez; Jan Reedijk; Antoni Llobet

Dalton Transactions | 2006

New antitumour active platinum compounds containing carboxylate ligands in trans geometry: synthesis, crystal structure and biological activity

Steven van Zutphen; Elena Pantoja; Rosario Soriano; Carlos Soro; Duncan M. Tooke; Anthony L. Spek; Hans den Dulk; Jaap Brouwer; Jan Reedijk

Bioorganic & Medicinal Chemistry Letters | 2004

The β-glucuronyl-based prodrug strategy allows for its application on β-glucuronyl-platinum conjugates

Reynier A. Tromp; Stella S. G. E. van Boom; C Marco Timmers; Steven van Zutphen; Gijsbert A. van der Marel; Herman S. Overkleeft; Jacques H. van Boom; Jan Reedijk

Inorganica Chimica Acta | 2006

In vitro antitumor activity and interaction with DNA model bases of cis-[PtCl2(iPram)(azole)] complexes and comparison with their trans analogues

Elena Pantoja; Agata Gallipoli; Steven van Zutphen; Duncan M. Tooke; Anthony L. Spek; Carmen Navarro-Ranninger; Jan Reedijk

Journal of Inorganic Biochemistry | 2005

Probing the potential of platinum(II) complexes for the inhibition of thiol-dependent enzymatic activity.

Steven van Zutphen; Marianne Kraus; Christoph Driessen; Gijs A. van der Marel; Herman S. Overkleeft; Jan Reedijk

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Jan Reedijk

Leiden University

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Hans den Dulk

Leiden University

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Herman S. Overkleeft

Leiden University

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Jaap Brouwer

Leiden University

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Anthony L. Spek

Utrecht University

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Gijs A. van der Marel

Leiden University

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Duncan M. Tooke

Utrecht University

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Elena Pantoja

Leiden University

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Marc S. Robillard

Leiden University

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Agata Gallipoli

Leiden University

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