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Dive into the research topics where Suteaki Shioya is active.

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Featured researches published by Suteaki Shioya.


Engineering in Life Sciences | 2015

5‐Aminolevulinic acid promotes callus growth and paclitaxel production in light‐grown Taxus cuspidata suspension cultures

Shinjiro Yamamoto; Shuhei Hayashi; Shintaro Furusaki; Suteaki Shioya

Cultured plant cells generally produce low levels of secondary metabolites, and elicitors of secondary metabolites usually inhibit callus growth. The aim of this study was to determine the effect of 5‐aminolevulinic acid (ALA), a chlorophyll precursor that promotes plant growth, on callus induction from leaves of Taxus cuspidata, and on callus growth on solid medium. ALA at 0.76, 7.6, and 76 μM had similar effects on callus induction and growth, while ALA at 760 μM had negative effects. Next, the effects of ALA concentrations on callus growth and paclitaxel production in suspension cultures in the dark were evaluated. The results showed that 0.76 and 7.6 μM ALA stimulated growth and paclitaxel production, while 76 μM ALA had negative effects. ALA is thought to promote cellular activity under light conditions. Therefore, the effects of light intensity on callus growth and paclitaxel production in the presence of ALA were evaluated. Our results showed that the best conditions for callus growth and paclitaxel production were 7.6 μM ALA under photosynthetically active radiation of 12 μmol photons m−2 s−1. Callus growth and paclitaxel production were inhibited under stronger light (24 μmol photons m−2 s−1). Together, these results show that ALA promoted callus growth and the production of paclitaxel by light‐grown cultured T. cuspidata cells.


Applied Microbiology and Biotechnology | 2010

Ethanol production from biomass by repetitive solid-state fed-batch fermentation with continuous recovery of ethanol

Churairat Moukamnerd; Masahiro Kino-oka; Minetaka Sugiyama; Yoshinobu Kaneko; Chuenchit Boonchird; Satoshi Harashima; Hideo Noda; Kazuaki Ninomiya; Suteaki Shioya; Yoshio Katakura


Asia-Pacific Journal of Chemical Engineering | 2014

A new bioreactor for paclitaxel production based on foam separation

Kohei Taura; Shinjiro Yamamoto; Shuhei Hayashi; Shintaro Furusaki; Suteaki Shioya


Solvent Extraction Research and Development-japan | 2013

Enhanced Paclitaxel Production by Addition of Water-Soluble 5-Aminolevulinic Acid and In Situ Extraction with Lauryl Alcohol in A Suspension Callus Culture

Kohei Taura; Shinjiro Yamamoto; Shuhei Hayashi; Suteaki Shioya


Solvent Extraction Research and Development-japan | 2014

Effect of Lauryl Alcohol on Production of Taxanes in a Suspension Callus Culture

Shinjiro Yamamoto; Kohei Taura; Shuhei Hayashi; Suteaki Shioya


Encyclopedia of Industrial Biotechnology | 2010

Mixed Culture Processes

Suteaki Shioya


Journal of Bioscience and Bioengineering | 2009

Improvement of shear stress tolerance of enzymes in the existence of water-miscible ionic liquids

Shuhei Hayashi; Yuya Takezaki; Noriyuki Konishi; Kaori Oshima; Shintaro Furusaki; Shinjiro Yamamoto; Suteaki Shioya


Archive | 2006

Responses of Different Strains of Saccharomyces cerevisiae to Osmotic Stress (Tindak Balas Pelbagai Strain Saccharomyces cerevisiae Terhadap Tekanan Osmotik)

Noorhisham Tan Kofli; Keisuke Nagahisa; Hiroshi Shimizu; Suteaki Shioya


Chinese Journal of Biotechnology | 1995

Modeling of penicillin G hydrolysis to 6-APA in an immobilized enzyme-ion exchange system.

Chen J; Takeshi Omasa; Yoshio Katakura; Suteaki Shioya; Suga K


Solvent Extraction Research and Development-japan | 2014

Enhancement of Taxane Production by the Combination of in situ Extraction with Lauryl Alcohol and Elicitation by Methyl Jasmonate in a Suspension Callus Culture

Shinjiro Yamamoto; Hiroki Koga; Shuhei Hayashi; Suteaki Shioya

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Hiroshi Shimizu

Massachusetts Institute of Technology

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