Network


Latest external collaboration on country level. Dive into details by clicking on the dots.

Hotspot


Dive into the research topics where Yong Koy Bong is active.

Publication


Featured researches published by Yong Koy Bong.


Journal of Organic Chemistry | 2018

Baeyer–Villiger Monooxygenase-Mediated Synthesis of Esomeprazole As an Alternative for Kagan Sulfoxidation

Yong Koy Bong; Shiwei Song; Jovana Nazor; Michael Vogel; Magnus Widegren; Derek Smith; Steven J. Collier; Robert John Wilson; S. M. Palanivel; Karthik Narayanaswamy; Ben Mijts; Michael D. Clay; Ryan Fong; Jeff Colbeck; Amritha Appaswami; Sheela Muley; Jun Zhu; Xiyun Zhang; Jack Liang; David Entwistle

A wild-type Baeyer-Villiger monooxygenase was engineered to overcome numerous liabilities in order to mediate a commercial oxidation of pyrmetazole to esomeprazole, using air as the terminal oxidant in an almost exclusively aqueous reaction matrix. The developed enzyme and process compares favorably to the incumbent Kagan inspired chemocatalytic oxidation, as esomeprazole was isolated in 87% yield, in >99% purity, with an enantiomeric excess of >99%.


Archive | 2010

Synthesis of prazole compounds

Yong Koy Bong; Michael D. Clay; Steven J. Collier; Benjamin Mijts; Michael Vogel; Xiyun Zhang; Jun Zhu; Jovana Nazor; Derek Smith; Shiwei Song


Archive | 2010

Ketoreductase-mediated stereoselective route to alpha chloroalcohols

Yong Koy Bong; Michael Vogel; Steven J. Collier; Vesna Mitchell; Jagadeesh Mavinahalli


Archive | 2013

BIOCATALYSTS AND METHODS FOR HYDROXYLATION OF CHEMICAL COMPOUNDS

Haibin Chen; Yong Koy Bong; Fabien Louis Cabirol; Anupam Gohel; Tao Li; Jeffrey C. Moore; Martina Quintanar-Audelo; Hong Yang; Steven J. Collier; Derek Smith


Archive | 2011

Biocatalysts for ezetimibe synthesis

Michael A. Crowe; Oscar Alvizo; Behnaz Behrouzian; Yong Koy Bong; Steven J. Collier; Anupam Gohel; Jagadeesh Mavinahalli; Naga K. Modukuru; Emily Mundorff; Derek Smith; Shiwei Song; Wan Lin Yeo


Archive | 2013

Engineered proline hydroxylase polypeptides

Haibin Chen; Yong Koy Bong; Fabien Louis Cabirol; Anupam Gohel Prafulchandra; Tao Li; Jeffrey C. Moore; Martina Quintanar-Audelo; Yang Hong; Steven J. Collier; Derek Smith


Archive | 2011

Biocatalyseurs pour la synthèse d'ézétimibe

Michael A. Crowe; Oscar Alvizo; Behnaz Behrouzian; Yong Koy Bong; Steven J. Collier; Anupam Gohel; Jagadeesh Mavinahalli; Naga K. Modukuru; Emily Mundorff; Derek Smith; Shiwei Song; Wan Lin Yeo


Archive | 2011

Biokatalysatoren zur ezetimib-synthese

Michael A. Crowe; Oscar Alvizo; Behnaz Behrouzian; Yong Koy Bong; Steven J. Collier; Anupam Gohel; Jagadeesh Mavinahalli; Naga K. Modukuru; Emily Mundorff; Derek Smith; Shiwei Song; Wan Lin Yeo


Archive | 2010

Polypeptides for a ketoreductase-mediated stereoselective route to alpha chloroalcohols

Yong Koy Bong; Michael Vogel; Steven J. Collier; Vesna Mitchell; Jagadeesh Mavinahalli


Archive | 2010

Voie stéréosélective à médiation par une cétoréductase vers des alpha chloroalcools

Yong Koy Bong; Michael Vogel; Steven J. Collier; Vesna Mitchell; Jagadeesh Mavinahalli

Collaboration


Dive into the Yong Koy Bong's collaboration.

Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar

Xiyun Zhang

University of California

View shared research outputs
Researchain Logo
Decentralizing Knowledge