Yoshikazu Matsuzaki

A possible role of a nonadrenergic inhibitory nervous system in airway hyperreactivity

To investigate a possible role of a nonadrenergic inhibitory nervous system in airway hyperreactivity, we measured changes in RL and CL caused by electrical stimulation of cervical vagus nerve during the infusion of 5-HT, after treatment with atropine and propranolol in 18 cats. RL decreased to 56 +/- 3% (mean +/- SE) and CL increased to 186 +/- 13% of the prestimulated values, respectively, after stimulation. Hexamethonium diminished these responses significantly. Airway reactivity to 5-HT was reduced by continuous electrical stimulation of cervical vagus nerve in cats pretreated with atropine and propranolol. Hexamethonium potentiated airway reactivity to 5-HT. These results suggest that a nonadrenergic inhibitory nervous system could play an important role in the control of the bronchomotor tone and contribute to airway hyperreactivity.

Cholecystobronchial fistula with report of a case

SummaryA case of direct cholecystobronchial fistula was presented. It must be the second case of the disease reported in literatures and the first case diagnosed by means of endoscopic cholangiography. The present case was probably caused by gallbladder penetration with a gallstone after inflammatory adhesions occurring between the gallbladder and the diaphragm as well as the diaphragm and the lung. A radical operation was performed with a complete recovery. The etiology, diagnosis and treatment of the biliobronchial fistula were discussed.A case of direct cholecystobronchial fistula was presented. It must be the second case of the disease reported in literatures and the first case diagnosed by means of endoscopic cholangiography. The present case was probably caused by gallbladder penetration with a gallstone after inflammatory adhesions occurring between the gallbladder and the diaphragm as well as the diaphragm and the lung. A radical operation was performed with a complete recovery. The etiology, diagnosis and treatment of the biliobronchial fistula were discussed.