You Young Jo
Rural Development Administration
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Publication
Featured researches published by You Young Jo.
Journal of Biomedical Materials Research Part A | 2012
Ok Joo Lee; Jung Min Lee; Ji Heui Kim; Jin Kim; HaeYong Kweon; You Young Jo; Chan Hum Park
Silk fibroin (SF) from silkworms has been widely studied as a biomaterial. The degradation behavior of silk biomaterials is important for medical applications, but few studies have examined long-term degradation behavior in vivo. In this study, we investigated the degradation behavior of SF membranes in vitro and in vivo. For the in vitro assay, we observed degradation of silk membranes in phosphate buffered saline, culture media, and an enzyme (proteinase K) solution. In the proteinase K solution, 80% of the silk membranes degraded within 10 days. Silk membranes exhibited no cytotoxicity toward L929 cells and rat tissues. To investigate the degradation of silk membranes in vivo, they were implanted subcutaneously in rats and harvested 19 months after surgery. Scanning electron microscopy imaging and histological analysis of silk membrane explants showed that they broke into several pieces after 16 months. Results show that silk membranes are biocompatible and display excellent long-term degradation behavior when used as biomaterials.
Maxillofacial plastic and reconstructive surgery | 2014
Min Keun Kim; Ki Yeon Yoo; Kwang Jun Kwon; Seong-Gon Kim; Young Wook Park; Kwang Gill Lee; You Young Jo; Hae Yong Kweon
Purpose: This study evaluated powdered burn wound dressing materials from wild silkworm fibroin in an animal model. Methods: Fifteen rats were used in this experiment. Full-thickness 2×2 cm burn wounds were created on the back of rats under anesthesia. In the two experimental groups, the wounds were treated with two different dressing materials made from silkworm fibroin. In the Control Group, natural healing without any dressing material was set as control. The wound surface area was measured at five days, seven days and 14 days. Wound healing was evaluated by histologic analysis. Results: By gross observation, there were no infections or severe inflammations through 14 days post-injury. The differences among groups were statistically significant at seven days and 14 days, postoperatively (P <0.037 and 0.001, respectively). By post hoc test, the defect size was significantly smaller in experimental Group 1 compared with the Control Group and experimental Group 2 at seven days postoperatively (P =0.022 and 0.029, respectively). The difference between Group 1 and Group 2 was statistically significant at 14 days postoperatively (P <0.001). Group 1 and control also differed significantly (P =0.002). Group 1 showed a smaller residual scar than the Control Group and Group 2 at 14 days post-injury. Histologic analysis showed more re-epithelization in Groups 1 and 2 than in the Control Groups. Conclusion: Burn wound healing was accelerated with silk fibroin spun by wild silkworm Antheraea pernyi. There was no atypical inflammation with silk dressing materials. In conclusion, silk dressing materials can be used for treatment of burn wound.
International journal of industrial entomology | 2013
Hyun Seok; Sang Woon Lee; Seong-Gon Kim; Dong hyun Seo; Han Sung Kim; Hae Yong Kweon; You Young Jo; Tae Yeon Kang; Myung Jin Lee ; Weon Sik Chae
Archive | 2009
Hae Yong Kweon; Kwang Gill Lee; Seok Woo Kang; Joo Hong Yeo; Chan Hum Park; Jin Kim; Chun Hwoi Kim; You Young Jo; Soon Ok Woo; Sang Mi Han
International journal of industrial entomology | 2013
Hee-Yeon Cho; Young-Ae Baik; Suyeon Jeon; Yoon Hae Kwak; Hae Yong Kweon; You Young Jo; Kwang Gill Lee; Young Hwan Park; Dongchul Kang
Archive | 2015
You Young Jo; Hae Yong Kweon; Kwang Gill Lee; Joo Hong Yeo; Heui Sam Lee; Hyun Bok Kim
The Journal Of Korean Association of Maxillofacial Plastic and Reconstructive Surgeons | 2012
Sang Woon Lee; Yong Tae Park; Seong-Gon Kim; Hae Yong Kweon; You Young Jo; Heui Sam Lee
International journal of industrial entomology | 2012
Jong Ho Kim ; Bong Seob Shin; Jong Young Jeon ; HaeYong Kweon; You Young Jo; Heui Sam Lee; Kwang Gill Lee
The Journal Of Korean Association of Maxillofacial Plastic and Reconstructive Surgeons | 2011
Ki Yu Park; Kyo Hee Choi; Young Ju Park; Ji Young Song; Seong-Gon Kim; You Young Jo; Hae Yong Kweon; Seok Woo Kang
Archive | 2011
You Young Jo; Seok Woo Kang; Seong-Gon Kim; Hae Yong Kweon; Kwang-Gill Lee; Kang Sun Ryu