Alex Chortos
Stanford University
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Featured researches published by Alex Chortos.
Advanced Materials | 2013
Mallory L. Hammock; Alex Chortos; Benjamin C.-K. Tee; Jeffrey B.-H. Tok; Zhenan Bao
Human skin is a remarkable organ. It consists of an integrated, stretchable network of sensors that relay information about tactile and thermal stimuli to the brain, allowing us to maneuver within our environment safely and effectively. Interest in large-area networks of electronic devices inspired by human skin is motivated by the promise of creating autonomous intelligent robots and biomimetic prosthetics, among other applications. The development of electronic networks comprised of flexible, stretchable, and robust devices that are compatible with large-area implementation and integrated with multiple functionalities is a testament to the progress in developing an electronic skin (e-skin) akin to human skin. E-skins are already capable of providing augmented performance over their organic counterpart, both in superior spatial resolution and thermal sensitivity. They could be further improved through the incorporation of additional functionalities (e.g., chemical and biological sensing) and desired properties (e.g., biodegradability and self-powering). Continued rapid progress in this area is promising for the development of a fully integrated e-skin in the near future.
Nature Materials | 2016
Alex Chortos; Jia Liu; Zhenan Bao
Skin plays an important role in mediating our interactions with the world. Recreating the properties of skin using electronic devices could have profound implications for prosthetics and medicine. The pursuit of artificial skin has inspired innovations in materials to imitate skins unique characteristics, including mechanical durability and stretchability, biodegradability, and the ability to measure a diversity of complex sensations over large areas. New materials and fabrication strategies are being developed to make mechanically compliant and multifunctional skin-like electronics, and improve brain/machine interfaces that enable transmission of the skins signals into the body. This Review will cover materials and devices designed for mimicking the skins ability to sense and generate biomimetic signals.
Science | 2015
Benjamin C.-K. Tee; Alex Chortos; Andre Berndt; Amanda Kim Nguyen; Ariane Tom; Allister F. McGuire; Ziliang Carter Lin; Kevin Tien; Won-Gyu Bae; Huiliang Wang; Ping Mei; Ho-Hsiu Chou; Bianxiao Cui; Karl Deisseroth; Tse Nga Ng; Zhenan Bao
Sensing the force digitally Our skin provides us with a flexible waterproof barrier, but it also contains a sensor array that feels the world around us. This array provides feedback and helps us to avoid a hot object or increase the strength of our grip on an object that may be slipping away. Tee et al. describe an approach to simulate the mechanoreceptors of human skin, using pressure-sensitive foils and printed ring oscillators (see the Perspective by Anikeeva and Koppes). The sensor successfully converted pressure into a digital response in a pressure range comparable to that found in a human grip. Science, this issue p. 313; see also p. 274 An artificial skin based on flexible printed organic circuits and pressure sensors mimics the ability to sense physical force. [Also see Perspective by Anikeeva and Koppes] Human skin relies on cutaneous receptors that output digital signals for tactile sensing in which the intensity of stimulation is converted to a series of voltage pulses. We present a power-efficient skin-inspired mechanoreceptor with a flexible organic transistor circuit that transduces pressure into digital frequency signals directly. The output frequency ranges between 0 and 200 hertz, with a sublinear response to increasing force stimuli that mimics slow-adapting skin mechanoreceptors. The output of the sensors was further used to stimulate optogenetically engineered mouse somatosensory neurons of mouse cortex in vitro, achieving stimulated pulses in accordance with pressure levels. This work represents a step toward the design and use of large-area organic electronic skins with neural-integrated touch feedback for replacement limbs.
Nature | 2016
Jin Young Oh; Simon Rondeau-Gagné; Yu-Cheng Chiu; Alex Chortos; Franziska Lissel; Ging-Ji Nathan Wang; Bob C. Schroeder; Tadanori Kurosawa; Jeffrey Lopez; Toru Katsumata; Jie Xu; Chenxin Zhu; Xiaodan Gu; Won-Gyu Bae; Yeongin Kim; Lihua Jin; Jong Won Chung; Jeffrey B.-H. Tok; Zhenan Bao
Thin-film field-effect transistors are essential elements of stretchable electronic devices for wearable electronics. All of the materials and components of such transistors need to be stretchable and mechanically robust. Although there has been recent progress towards stretchable conductors, the realization of stretchable semiconductors has focused mainly on strain-accommodating engineering of materials, or blending of nanofibres or nanowires into elastomers. An alternative approach relies on using semiconductors that are intrinsically stretchable, so that they can be fabricated using standard processing methods. Molecular stretchability can be enhanced when conjugated polymers, containing modified side-chains and segmented backbones, are infused with more flexible molecular building blocks. Here we present a design concept for stretchable semiconducting polymers, which involves introducing chemical moieties to promote dynamic non-covalent crosslinking of the conjugated polymers. These non-covalent crosslinking moieties are able to undergo an energy dissipation mechanism through breakage of bonds when strain is applied, while retaining high charge transport abilities. As a result, our polymer is able to recover its high field-effect mobility performance (more than 1 square centimetre per volt per second) even after a hundred cycles at 100 per cent applied strain. Organic thin-film field-effect transistors fabricated from these materials exhibited mobility as high as 1.3 square centimetres per volt per second and a high on/off current ratio exceeding a million. The field-effect mobility remained as high as 1.12 square centimetres per volt per second at 100 per cent strain along the direction perpendicular to the strain. The field-effect mobility of damaged devices can be almost fully recovered after a solvent and thermal healing treatment. Finally, we successfully fabricated a skin-inspired stretchable organic transistor operating under deformations that might be expected in a wearable device.
Nature Communications | 2015
Ho-Hsiu Chou; Amanda Nguyen; Alex Chortos; John W. F. To; Chien Lu; Jianguo Mei; Tadanori Kurosawa; Won-Gyu Bae; Jeffrey B.-H. Tok; Zhenan Bao
Some animals, such as the chameleon and cephalopod, have the remarkable capability to change their skin colour. This unique characteristic has long inspired scientists to develop materials and devices to mimic such a function. However, it requires the complex integration of stretchability, colour-changing and tactile sensing. Here we show an all-solution processed chameleon-inspired stretchable electronic skin (e-skin), in which the e-skin colour can easily be controlled through varying the applied pressure along with the applied pressure duration. As such, the e-skins colour change can also be in turn utilized to distinguish the pressure applied. The integration of the stretchable, highly tunable resistive pressure sensor and the fully stretchable organic electrochromic device enables the demonstration of a stretchable electrochromically active e-skin with tactile-sensing control. This system will have wide range applications such as interactive wearable devices, artificial prosthetics and smart robots.
Advanced Materials | 2015
Changhyun Pang; Ja Hoon Koo; Amanda Nguyen; Jeffrey M. Caves; Myung-Gil Kim; Alex Chortos; Kwanpyo Kim; Paul J. Wang; Jeffrey B.-H. Tok; Zhenan Bao
A bioinspired microhairy sensor is developed to enable ultraconformability on nonflat surfaces and significant enhancement in the signal-to-noise ratio of the retrieved signals. The device shows ≈12 times increase in the signal-to-noise ratio in the generated capacitive signals, allowing the ultraconformal microhair pressure sensors to be capable of measuring weak pulsations of internal jugular venous pulses stemming from a human neck.
Nature Communications | 2014
Lisa Y. Chen; Benjamin C.-K. Tee; Alex Chortos; Gregor Schwartz; Victor Tse; Darren J. Lipomi; H.-S. Philip Wong; Michael V. McConnell; Zhenan Bao
Continuous monitoring of internal physiological parameters is essential for critical care patients, but currently can only be practically achieved via tethered solutions. Here we report a wireless, real-time pressure monitoring system with passive, flexible, millimetre-scale sensors, scaled down to unprecedented dimensions of 1 × 1 × 0.1 cubic millimeters. This level of dimensional scaling is enabled by novel sensor design and detection schemes, which overcome the operating frequency limits of traditional strategies and exhibit insensitivity to lossy tissue environments. We demonstrate the use of this system to capture human pulse waveforms wirelessly in real time as well as to monitor in vivo intracranial pressure continuously in proof-of-concept mice studies using sensors down to 2.5 × 2.5 × 0.1 cubic millimeters. We further introduce printable wireless sensor arrays and show their use in real-time spatial pressure mapping. Looking forward, this technology has broader applications in continuous wireless monitoring of multiple physiological parameters for biomedical research and patient care.
Advanced Materials | 2015
Clementine M. Boutry; Amanda Nguyen; Qudus Omotayo Lawal; Alex Chortos; Simon Rondeau-Gagné; Zhenan Bao
An array of highly sensitive pressure sensors entirely made of biodegradable materials is presented, designed as a single-use flexible patch for application in cardiovascular monitoring. The high sensitivity in combination with fast response time is unprecedented when compared to recent reports on biodegradable pressure sensors (sensitivity three orders of magnitude higher), as illustrated by pulse wave velocity measurements, toward hypertension detection.
Advanced Materials | 2014
Alex Chortos; Josh Lim; John W. F. To; Michael Vosgueritchian; Thomas J. Dusseault; Tae Ho Kim; Sungwoo Hwang; Zhenan Bao
A. Chortos, J. Lim, J. W. F. To, Dr. M. Vosgueritchian, T. J. Dusseault, Prof. Z. Bao Department of Chemical Engineering Stanford University 381 North-South Mall , Stanford , CA , USA E-mail: zbao@stanford.edu T.-H. Kim, S. Hwang Nano Electronics Laboratory Samsung Advanced Institute of Technology Suwon 443–803 , Korea E-mail: swnano.hwang@samsung.com
Advanced Materials | 2016
Alex Chortos; Ghada I. Koleilat; Raphael Pfattner; Desheng Kong; Pei Lin; Roda Nur; Ting Lei; Huiliang Wang; Nan Liu; Ying-Chih Lai; Myung-Gil Kim; Jong Won Chung; Sangyoon Lee; Zhenan Bao
Mechanically durable stretchable trans-istors are fabricated using carbon nanotube electrical components and tough thermoplastic elastomers. After an initial conditioning step, the electrical characteristics remain constant with strain. The strain-dependent characteristics are similar in orthogonal stretching directions. Devices can be impacted with a hammer and punctured with a needle while remaining functional and stretchable.