Aline Oliveira Silveira

Analysis of 724 cases of primary head and neck squamous cell carcinoma (HNSCC) with a focus on young patients and p53 immunolocalization

This study evaluated 724 primary head and neck squamous cell carcinoma (HNSCC) in young and old patients, with regard to clinical profile and immunohistochemical expression of p53 protein. Associations among age, epidemiological and clinicopathological parameters, and survival analysis were evaluated. HNSCC in young people occurred in 14.5% (median age 40.7years; male-to-female ratio 5.9:1). A statistical association was demonstrated between age and family history of cancer, and between age and anatomical site. Among older patients, a higher presence of disease was noted in posterior sites. Expression of p53 was found in 71.7% of the samples and a higher expression was noted in lesions of young patients. Survival analysis showed that the age parameter is not a reliable prognostic factor for HNSCC. Among young patients, cervical metastasis was associated with worse survival. The presence of a family history of cancer in young patients could indicate genetic susceptibility and molecular disturbances in the p53 pathway in HNSCC of young and older patients seem to be distinct.

A experiência de interação da família que vivencia a doença e hospitalização da criança

A partir del cuestionamiento sobre cuales son los significados atribuidos por la familia a las interaccionesvivenciadas a lo largo de la hospitalizacion del nino, este estudio busco comprender la experiencia interaccionalde la familia en el hospital pediatrico asi como identificar las intervenciones consideradas efectivas en laperspectiva de la familia. El estudio tuvo como orientacion teorica el Interacionismo Simbolico, que diosustentacion al proceso del analisis de los datos, y tuvo como referencial metodologico la Teoria Fundamentadaen los Datos. Participaron del estudio 6 familias de ninos hospitalizados. Los resultados permitieron identificardos fenomenos: “sintiendose segura para asumir riesgos” y “sintiendose insegura para asumir riesgos”,representativos de los significados simbolicos atribuidos a contextos relacionales que emergen de la interaccionde la familia con los profesionales de salud. Los conceptos identificados contribuyen en especial para ampliarla comprension de la aproximacion de cuidado centrada en la familia, ademas de proporcionar un camino a lareflexion con respecto a la interaccion e intervencion con la familia en la practica pediatrica.DESCRIPTORES: familia; nino; enfermedad; hospitalizacion; relaciones interpersonales; bienestar familiar;enfermeria de la familia

Família como categoria de análise e campo de investigação em enfermagem

The increasing information about family in nursing literature expresses the progress in this area of knowledge. The research contribution on family nursing has included the illness experience, and both the context of care and interventions. The increase of family research in nursing studies demands consideration regarding the research quality, in view of the complexity of the studies that deal with family. Researching family represents more than defining a unique group of study. The aim of this study was to discuss theoretical and methodological aspects which should be taken into account by the researchers in their work with families. The reflections and challenges when studying family and illness have been described in this work and represent our 10-year experience investigating families and illnesses in our research group.The increasing information about family in nursing literature expresses the progress in this area of knowledge. The research contribution on family nursing has included the illness experience, and both the context of care and interventions. The increase of family research in nursing studies demands consideration regarding the research quality, in view of the complexity of the studies that deal with family. Researching family represents more than defining a unique group of study. The aim of this study was to discuss theoretical and methodological aspects which should be taken into account by the researchers in their work with families. The reflections and challenges when studying family and illness have been described in this work and represent our 10year experience investigating families and illnesses in our research group.

Interaction experience for families who lives with their child's disease and hospitalization

A partir del cuestionamiento sobre cuales son los significados atribuidos por la familia a las interaccionesvivenciadas a lo largo de la hospitalizacion del nino, este estudio busco comprender la experiencia interaccionalde la familia en el hospital pediatrico asi como identificar las intervenciones consideradas efectivas en laperspectiva de la familia. El estudio tuvo como orientacion teorica el Interacionismo Simbolico, que diosustentacion al proceso del analisis de los datos, y tuvo como referencial metodologico la Teoria Fundamentadaen los Datos. Participaron del estudio 6 familias de ninos hospitalizados. Los resultados permitieron identificardos fenomenos: “sintiendose segura para asumir riesgos” y “sintiendose insegura para asumir riesgos”,representativos de los significados simbolicos atribuidos a contextos relacionales que emergen de la interaccionde la familia con los profesionales de salud. Los conceptos identificados contribuyen en especial para ampliarla comprension de la aproximacion de cuidado centrada en la familia, ademas de proporcionar un camino a lareflexion con respecto a la interaccion e intervencion con la familia en la practica pediatrica.DESCRIPTORES: familia; nino; enfermedad; hospitalizacion; relaciones interpersonales; bienestar familiar;enfermeria de la familia

Family as an analysis category and research field in nursing

The increasing information about family in nursing literature expresses the progress in this area of knowledge. The research contribution on family nursing has included the illness experience, and both the context of care and interventions. The increase of family research in nursing studies demands consideration regarding the research quality, in view of the complexity of the studies that deal with family. Researching family represents more than defining a unique group of study. The aim of this study was to discuss theoretical and methodological aspects which should be taken into account by the researchers in their work with families. The reflections and challenges when studying family and illness have been described in this work and represent our 10-year experience investigating families and illnesses in our research group.The increasing information about family in nursing literature expresses the progress in this area of knowledge. The research contribution on family nursing has included the illness experience, and both the context of care and interventions. The increase of family research in nursing studies demands consideration regarding the research quality, in view of the complexity of the studies that deal with family. Researching family represents more than defining a unique group of study. The aim of this study was to discuss theoretical and methodological aspects which should be taken into account by the researchers in their work with families. The reflections and challenges when studying family and illness have been described in this work and represent our 10year experience investigating families and illnesses in our research group.

Crenças e práticas parentais no cuidado domiciliar da criança nascida prematura

The aim of the study was to identify parenting practices and beliefs regarding in-home care of premature infants. It is an observational, crosssectional research carried out with 31 parents of premature babies. Data collection tools were: family records; and the “parental beliefs and care practices scale (E-CPPC)”. Data analysis was based on descriptive and inferential statistics (Pearson correlation coefficient). An autonomousrelational parenting style, characterized by a combination of distal and proximal care was identified. The main relational patterns found were overprotection, the difficulties of performing the care routine and child stimulation. Important parenting styles in that context were identified. The study highlights the need for systematic interventions that promote positive parenting abilities. New studies in different contexts are needed to generate knowledge that supports public policies focusing on domiciliary follow-up of premature infants and their parents.

Familia como categoria de análisis y campo de investigación en enfermeria

The increasing information about family in nursing literature expresses the progress in this area of knowledge. The research contribution on family nursing has included the illness experience, and both the context of care and interventions. The increase of family research in nursing studies demands consideration regarding the research quality, in view of the complexity of the studies that deal with family. Researching family represents more than defining a unique group of study. The aim of this study was to discuss theoretical and methodological aspects which should be taken into account by the researchers in their work with families. The reflections and challenges when studying family and illness have been described in this work and represent our 10-year experience investigating families and illnesses in our research group.The increasing information about family in nursing literature expresses the progress in this area of knowledge. The research contribution on family nursing has included the illness experience, and both the context of care and interventions. The increase of family research in nursing studies demands consideration regarding the research quality, in view of the complexity of the studies that deal with family. Researching family represents more than defining a unique group of study. The aim of this study was to discuss theoretical and methodological aspects which should be taken into account by the researchers in their work with families. The reflections and challenges when studying family and illness have been described in this work and represent our 10year experience investigating families and illnesses in our research group.

La experiencia de interacción de la familia que vive la enfermedad y hospitalización del niño

A partir del cuestionamiento sobre cuales son los significados atribuidos por la familia a las interaccionesvivenciadas a lo largo de la hospitalizacion del nino, este estudio busco comprender la experiencia interaccionalde la familia en el hospital pediatrico asi como identificar las intervenciones consideradas efectivas en laperspectiva de la familia. El estudio tuvo como orientacion teorica el Interacionismo Simbolico, que diosustentacion al proceso del analisis de los datos, y tuvo como referencial metodologico la Teoria Fundamentadaen los Datos. Participaron del estudio 6 familias de ninos hospitalizados. Los resultados permitieron identificardos fenomenos: “sintiendose segura para asumir riesgos” y “sintiendose insegura para asumir riesgos”,representativos de los significados simbolicos atribuidos a contextos relacionales que emergen de la interaccionde la familia con los profesionales de salud. Los conceptos identificados contribuyen en especial para ampliarla comprension de la aproximacion de cuidado centrada en la familia, ademas de proporcionar un camino a lareflexion con respecto a la interaccion e intervencion con la familia en la practica pediatrica.DESCRIPTORES: familia; nino; enfermedad; hospitalizacion; relaciones interpersonales; bienestar familiar;enfermeria de la familia