Danny P. C. McGee | Researchain

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Tetrahedron Letters | 1982

Silylated derivatives of arabinonucleosides

Kelvin K. Ogilvie; Gholam Hosein Hakimelahi; Zbigniew A. Proba; Danny P. C. McGee

Abstract Procedure have been developed which allow for the selective derivatization of arabinonucleosides at the 5′− or 2′− and 5′− or 3′− and 5′− positions.

Nucleosides, Nucleotides & Nucleic Acids | 1990

Synthesis and antiviral activity of the 3-deaza analogue of 9-((1,3-dihydroxy-2-propoxy)methyl)guanine

Danny P. C. McGee; John C. Martin; Donald F. Smee; Julien P. H. Verheyden

Abstract The synthesis of 3-deaza-DHPG 2 and its positional isomer 10 via the acid catalysed fusion of imidazole 3 and acetoxymethylglycerol 4 is described. Analogue 2 has activity against herpes simplex viruses and cytomegalovirus.

Synthetic Communications | 1988

Synthesis of 9-((1,3-Dihydroxy-2-Propoxy)Methyl)Guanine (Dhpg) Via Condensation Of N2sp>u>9-Diacetylguanine With A Sulfinylmethyl Ether

Danny P. C. McGee; John C. Martin; Julien P. H. Verheyden

Abstract The condensation of N2sp>u>9-diacetylguanine (8) with methylsulfinylmethyl ether 7 gave DHPG precursor 9.

Journal of Medicinal Chemistry | 1986

Synthesis and antiherpes virus activity of phosphate and phosphonate derivatives of 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine.

Ernest J. Prisbe; John C. Martin; Danny P. C. McGee; Molly F. Barker; Donald F. Smee; Arit E. Duke; Thomas R. Matthews; Julien P. H. Verheyden

Journal of Medicinal Chemistry | 1986

Synthesis and anti-herpes-virus activity of acyclic 2'-deoxyguanosine analogues related to 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine

John C. Martin; Danny P. C. McGee; Gary A. Jeffrey; Doug W. Hobbs; Donald F. Smee; Thomas R. Matthews; Julian P. H. Verheyden

Journal of Medicinal Chemistry | 2006

Design and synthesis of 5-aryl-pyridone-carboxamides as inhibitors of anaplastic lymphoma kinase.

Rongshi Li; Liquan Xue; Tong Zhu; Qin Jiang; Xiaoli Cui; Zheng Yan; Danny P. C. McGee; Jian Wang; Vidyasagar Reddy Gantla; Jason C. Pickens; Doug McGrath; Alexander Chucholowski; Stephan W. Morris; Thomas R. Webb

Journal of Medicinal Chemistry | 1988

Synthesis and antiviral evaluation of 6'-substituted aristeromycins: potential mechanism-based inhibitors of S-adenosylhomocysteine hydrolase

G. V. Bindu Madhavan; Danny P. C. McGee; Robert M. Rydzewski; Richard Boehme; John C. Martin; Ernest J. Prisbe

Journal of Pharmaceutical Sciences | 1987

Synthesis and Antiviral Activity of Various Esters of 9-[(1,3-Dihydroxy-2-propoxy)methyl]guanine

John C. Martin; Michael A. Tippie; Danny P. C. McGee; Julien P. H. Verheyden

Archive | 2006

Heterocyclic compounds as tyrosine kinase modulators

Alexey Anikin; Vidyasagar Reddy Gantla; Vlad Edward Gregor; Luyong Jiang; Yahua Liu; Danny P. C. McGee; Charles Mikel; Jason C. Pickens; Thomas R. Webb; Yan Zheng; Tong Zhu; Aleksander Kadushkin; Sergey Zozulya; Alexander Chucholowski; Douglas Eric Mcgrath; Sergey Sviridov

Canadian Journal of Chemistry | 1986