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Dive into the research topics where Isao Saito is active.

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Featured researches published by Isao Saito.


Phytochemistry | 1989

Coumarins of Merrillia caloxylon

Muhamad Bin Zakaria; Isao Saito; Teruo Matsuura

Abstract From the roots of Merrillia caloxylon the five isoprenylcoumarins (−)-sibiricin, (−)-phebalosin, (−)-murrangatin, (−)-mexoticin and merillin were isolated.


Nucleic acids research. Supplement (2001) | 2001

Molecular design of hairpin imidazole-pyrrole polyamide for effective DNA alkylation

Toshikazu Bando; Akihiko Narita; Isao Saito; Hiroshi Sugiyama

A new type of hairpin polyamide-CPI conjugate possessing a vinyl linker has been synthesized. Sequence-selective alkylation of double-stranded DNA by conjugates was investigated by high resolution denaturing gel electrophoresis using 450 bp DNA fragments. Highly-efficient DNA alkylation predominantly occurs at the purines of 5-(A/T)G(T/A)CPu-3 site at nanomolar concentration.


Archive | 1996

Hammerhead-like nucleic acid analogues and their synthesis

Hiroshi Sugiyama; Ken Hatano; Isao Saito; Takayoshi Uchida; Yoko Matsuda; Kiyoshi Uchida


Archive | 1999

Compounds alkylating specific base sequence of DNA and method for synthesizing the same

Hiroshi Sugiyama; Zhi Fu Tao; Isao Saito


Archive | 2002

Method of the solid phase synthesis of pyrrole-imidazole polyamide

Hiroshi Sugiyama; Hirokazu Iida; Isao Saito; Takashi Saito


Archive | 1989

Method for deoxygenation of alcohols

Isao Saito; Teruo Matsuura; Hideyuki Ikehira


Archive | 2001

Interstrand crosslinking agents for dna and compounds therefor

Hiroshi Sugiyama; Toshikazu Bando; Hirokazu Iida; Isao Saito


Archive | 2003

Novel hairpin polyamide

Hiroshi Sugiyama; Toshikazu Bando; Isao Saito


Archive | 2000

Development of method for screening physiologically active pyrrole imidazole derivative

Hiroshi Sugiyama; Isao Saito; Hirokazu Iida


Archive | 2000

Compounds capable of cleaving double-stranded dna and method of utilization of the same

Hiroshi Sugiyama; Zhi-Fu Tao; Isao Saito

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Toshikazu Bando

Tokyo Medical and Dental University

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Hirokazu Iida

Tokyo Medical and Dental University

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Zhi-Fu Tao

Tokyo Medical and Dental University

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Akihiko Narita

Tokyo Medical and Dental University

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