Marcel Frans Leopold De Bruyn
Janssen Pharmaceutica
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Marcel Frans Leopold De Bruyn.
Bioorganic & Medicinal Chemistry Letters | 1995
Guy Rosalia Eugene Van Lommen; Marcel Frans Leopold De Bruyn; Marc Francis Josephine Schroven; Wim Gaston Verschueren; W. J. Janssens; Jan Verrelst; Josée E. Leysen
Abstract The synthesis and SAR of a series of non-indole 5HT1D agonists is described. The most interesting molecule of this series is compound 13, alniditan. It is active as a constrictor of the saphenous vein of the dog and of the pig basilar artery with ED50 values of 9.09×10−9M and 2.29×10−8M respectively, and it has high affinities to the 5HT1D-receptor and to the 5HT1D-receptor with pKi values of 8.6 and 8.3 respectively.
Archive | 1984
Guy Rosalia Eugene Van Lommen; Marcel Frans Leopold De Bruyn; Marc Francis Josephine Schroven
Archive | 1998
Piet Tom Bert Paul Wigerinck; Wim Gaston Verschueren; Marc Francis Josephine Schroven; Marcel Frans Leopold De Bruyn
Archive | 1994
Guy Rosalia Eugene Van Lommen; Piet Tom Bert Paul Wigerinck; Marcel Frans Leopold De Bruyn; Wim Gaston Verschueren; Marc Francis Josephine Schroven
Drug Development Research | 1986
Georges Henri Paul Van Daele; Marcel Frans Leopold De Bruyn; Francois Maria Sommen; Marcel Janssen; Jan M. Van Nueten; Jan A.J. Schuurkes; C. J. E. Niemegeers; Josée E. Leysen
Archive | 1997
Guy Rosalia Eugene Van Lommen; Marcel Frans Leopold De Bruyn; Piet Tom Bert Paul Wigerinck
Archive | 2006
Marcel Frans Leopold De Bruyn; Gregor James Macdonald; Ludo Edmond Josephine Kennis; Xavier Langlois; Frans Alfons Maria Van Den Keybus; Yves Emiel Maria Van Roosbroeck
Archive | 2007
Johannes Wilhelmus John F. Thuring; Theodorus Dinklo; Anne Simone Josephine Lesage; Marcel Frans Leopold De Bruyn; Wei Zhuang
Archive | 2000
Marcel Frans Leopold De Bruyn; Kristof Van Emelen; Piet Tom Bert Paul Wigerinck; Wim Gaston Verschueren
Archive | 2000
Kristof Van Emelen; Marcel Frans Leopold De Bruyn
