Oscar Alvizo
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Publication
Featured researches published by Oscar Alvizo.
Angewandte Chemie | 2018
Feng Xu; Birgit Kosjek; Fabien Louis Cabirol; Haibin Chen; Richard Desmond; Jeonghan Park; Anupam Gohel; Steven J. Collier; Derek Smith; Zhuqing Liu; Jacob M. Janey; John Y. L. Chung; Oscar Alvizo
Described here is an efficient stereoselective synthesis of vibegron enabled by an enzymatic dynamic kinetic reduction that proceeds in a high-pH environment. To overcome enzyme performance limitations under these conditions, a ketoreductase was evolved by a computationally and structurally aided strategy to increase cofactor stability through tighter binding.
Archive | 2011
Scott Novick; Oscar Alvizo
Archive | 2010
Oscar Alvizo; Steven J. Collier; Joerg Hennemann; Seong Ho Oh; Wenjuan Zha
Archive | 2010
Lynne Gilson; Steven J. Collier; Joly Sukumaran; Wan Lin Yeo; Oscar Alvizo; Ee Ling Teo; Robert John Wilson; Junye Xu
Organic Letters | 2016
Alan M. Hyde; Zhijian Liu; Birgit Kosjek; Lushi Tan; Artis Klapars; Eric R. Ashley; Yong-Li Zhong; Oscar Alvizo; Nicholas J. Agard; Guiquan Liu; Xiuyan Gu; Nobuyoshi Yasuda; John Limanto; Mark A. Huffman; David M. Tschaen
Archive | 2011
Oscar Alvizo; Michael R. Benoit; Scott Novick
Archive | 2012
Oscar Alvizo; Galit Meshulam-Simon; Amy Lum; Dayal Saran
Archive | 2016
Ee Lui Ang; Oscar Alvizo; Behnaz Behrouzian; Michael D. Clay; Steven J. Collier; Ellen Eberhard; Fu Fan; Shiwei Song; Derek Smith; Magnus Widegren; Robert John Wilson; Junye Xu; Jun Zhu
Archive | 2011
Oscar Alvizo; Robert Mcdaniel; Benjamin Mijts
Archive | 2011
Michael A. Crowe; Oscar Alvizo; Behnaz Behrouzian; Yong Koy Bong; Steven J. Collier; Anupam Gohel; Jagadeesh Mavinahalli; Naga K. Modukuru; Emily Mundorff; Derek Smith; Shiwei Song; Wan Lin Yeo
