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Dive into the research topics where Stanton Furst Mchardy is active.

Publication


Featured researches published by Stanton Furst Mchardy.


Bioorganic & Medicinal Chemistry Letters | 2010

Biaryl piperidines as potent and selective delta opioid receptor ligands

Spiros Liras; Stanton Furst Mchardy; Martin Patrick Allen; Barb E. Segelstein; Steven D. Heck; Dianne K. Bryce; Anne W. Schmidt; Michelle Vanase-Frawley; Ernesto Callegari; Stafford McLean

The design and synthesis of novel opiates are reported. Based on the message-address principle a novel class of 4,4- and 3,3-biaryl piperidines was designed and synthesized. Biological evaluation confirmed that these compounds exhibit high affinity and selectivity for the delta opioid receptor. Key structure-activity relationships that influence affinity, selectivity, functional activity and clearance are reported.


Archive | 2007

Tetralines antagonists of the h-3 receptor

Stanton Furst Mchardy; Vinod D. Parikh


Archive | 2006

Bicyclic [3.1.0] heteroaryl amides as type i glycine transport inhibitors

Stanton Furst Mchardy; John A. Lowe


Archive | 2004

Pharmaceutical composition for the prevention and treatment of addiction in a mammal

Jotham Wadsworth Coe; Philip A. Iredale; Stanton Furst Mchardy; Stafford McLean


Archive | 2007

Heteroaryl amides as type i glycine transport inhibitors

Iii John Adams Lowe; Subas M. Sakya; Mark Allen Sanner; Jotham Wadsworth Coe; Stanton Furst Mchardy


Archive | 2002

3-Azabicyclo[3.1.0]hexane derivatives

Stanton Furst Mchardy; Spiros Liras; Steven D. Heck


Archive | 2004

4-Phenyl-piperidine compounds and their use as modulators of opioid receptors

Stanton Furst Mchardy; Spiros Liras; Sara Ann Guediche; Jotham Wadsworth Coe


Archive | 2004

3-Azabicyclo[3.2.1]octane derivatives

Jotham Wadsworth Pfizer Global R D Coe; Stanton Furst Mchardy; Crystal G. Bashore


Archive | 2004

2-Azabicyclo[3.3.1]nonane derivatives

Jotham Wadsworth Coe; Stanton Furst Mchardy


MedChemComm | 2011

Discovery of CP-866,087, a mu opioid receptor antagonist for the treatment of alcohol abuse and dependence

Stanton Furst Mchardy; Steven D. Heck; Sara Ann Guediche; Monica Kalman; Martin Patrick Allen; Meihua Tu; Dianne K. Bryce; Anne W. Schmidt; Michelle Vanase-Frawley; Ernesto Callegari; Shawn D. Doran; Nicholas J. Grahame; Stafford McLean; Spiros Liras

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