Ye. G. Ushenko

Investigation of 2D Mueller matrix structure of biological tissues for pre-clinical diagnostics of their pathological states

The interconnection between the geometry of biological tissue (BT) structure and their polarization properties has been studied. It has been shown that for physiologically normal BT, the polarization properties of radiation scattered on architectonic nets formed by protein fibrils have a fractal character. Pathological changes of BT architectonics are accompanied by the transformation of self-similar structure of 2D Mueller-matrix elements into stochastic and statistic ones.

Polarization singularities of the object field of skin surface

The paper deals with the investigation of formation mechanisms of laser radiation polarization structure scattered by an optically thin surface layer of human skin in two registration zones: a boundary field and a far zone of Fraunhofer diffraction. The conditions of forming polarization singularities by such an object in the scattered radiation field have been defined. Statistical and fractal polarization structure of object fields of physiologically normal and pathologically changed skin has been studied. It has been shown that polarization singularities of radiation scattered by physiologically normal skin samples have a fractal coordinate structure. It is characteristic for fields of pathologically changed skin to have a statistical coordinate structure of polarization singularities in all diffraction zones.

2-D tomography of biotissue images in pre-clinic diagnostics of their pre-cancer states

The correlation structure of 2-D Stokes vector parameters of physiologically normal and pathologicaly changed biotissues is investigated. The totality of diagnostically urgent interconnections between biotissue physiological state and statistical moments of 2-D Stokes vector parameters is found.

Fractal structure of biotissue polarization properties

The interconnection between geometry of biotissue structure with their polarization properties has been studied. It has been shown that for physiologically normal biotissues polarization properties of radiation scattered on architectonic nets formed by protein fibrils possess the fractal character. Pathological changes of biotissues architectonics are accompanied with the transformation of self-similar structure of Mueller-matrix images into stochastic and statistic ones.

Polarization speckle-reconstruction of biological tissues architectonics: Part 1. Polarization correlometry of birefringence architectonics: singular approach

The interconnection between topological and statistic (correlation) approaches in the description of mechanisms of forming polarization inhomogeneity of the biological objects images have been discovered.

Studies on automatic analysis of polarization images of tissues for early diagnosis of neoplastic transformation

The interrelations between statistics of the 1st-4th orders of the totality of Mueller-matrix images and geometric structure of birefringent architectonic nets of different morphological structure have been analyzed. It has been shown that the third and the fourth statistical moments of matrix elements two-dimensional distributions are the most sensitive to changing orientation structure of optically anisotropic protein fibrils of architectonics of physiologically normal and pathologically changed biological tissues.

Complex degree of mutual polarization for biological tissue coherent images

The article is directed to study of statistics of the complex degree of mutual polarization of biological tissues speckle-images. The totality of diagnostic criteria (skewness and kurtosis of two-dimensional distributions of complex degree of mutual polarization) of pathological changes of muscular, skin derma and bone tissues is defined.

Fractal structure of biotissues polarization properties for early diagnostic cancer changes

The interconnection between geometry of biotissue structure with their polarization properties has been studied. It has been shown that fractal character of polarization properties of physiologically normal biotissue transforms into a multifractal for a pathologically changed one.