Francesco Pinto Boeno

Glycemic, inflammatory and oxidative stress responses to different high-intensity training protocols in type 1 diabetes: A randomized clinical trial

AIMS To investigate the effects of high-intensity interval training (HIIT) and/or strength training (ST) on inflammatory, oxidative stress (OS) and glycemic parameters in type 1 diabetes (T1DM) patients. METHODS After a 4-week control period, volunteers were randomly assigned to 10-week HIIT, ST or ST + HIIT protocol, performed 3×/week. Blood biochemistry, anthropometric, strength and cardiopulmonary fitness variables were assessed. Outcomes were analyzed via generalized estimating equations (GEE), with Bonferroni post hoc analysis. RESULTS ST, HIIT and ST + HIIT improved glycemic (HbA1c and fasting glucose) and antioxidant parameters (total antioxidant capacity, catalase and superoxide dismutase activities), but not plasma inflammatory (C-reactive protein, TNF-α and IL-10) or OS markers (thiobarbituric acid-reactive substances, 8-hydroxy-2-deoxyguanosine and oxLDL) levels. Noteworthy, interventions reduced soluble receptors for advanced glycation end products levels. However, intracellular heat shock protein 70 content increased only after HIIT. While daily insulin dosage decreased only in the ST + HIIT group, all training models induced anthropometric and functional benefits. CONCLUSIONS Similar benefits afforded by ST, HIIT or ST + HIIT in T1DM people are associated with enhanced antioxidant systems and glucose-related parameter, even in a few weeks. From a practical clinical perspective, the performance of ST + HIIT may be advised for additional benefits regarding insulin dosage reduction.

Efeito agudo do exercício de força com restrição do fluxo sanguíneo sobre parâmetros antioxidantes em indivíduos jovens saudáveis

Abstract Background Strength training with blood flow restriction (STBFR) provokes similar neuromuscular adaptations to traditional strength training using low training loads. However, there is a need for better understanding of the repercussions for antioxidant parameters and vascular function. Objectives: The objective of the present study was to investigate the effects of a session of low intensity strength training with blood flow restriction, compared with high intensity and low intensity strength training without blood flow restriction, on the levels of nitric oxide products and antioxidant enzyme activity in healthy young men. Methods: Eleven young men performed three strength exercise sessions: low intensity with blood flow restriction (LIBFR), high intensity (HI), and low intensity (LI). Activity of the antioxidant enzymes catalase (CAT) and superoxide dismutase (SOD) was assessed and metabolites of nitric oxide (NOx) were assayed before and after each session. Results: There were no changes to NOx plasma levels under the different exercise conditions (p > 0.05). However, SOD activity exhibited a significant reduction after the LIBFR condition (p < 0.05), while CAT activity reduced significantly after the LI condition (p < 0.05). Conclusions: The results of this study suggest that one session of low intensity strength training with blood flow restriction does not reduce bioavailability of nitric oxide or induce redox imbalance in healthy young men.

Hypotensive Response to Continuous Aerobic and High-Intensity Interval Exercise Matched by Volume in Sedentary Subjects

Mailing Address: Thiago Rozales Ramis Rua Felizardo, 750. Postal Code: 90450-190, Jardim Botânico, Porto Alegre RS, Brazil. E-mail: thiago.ramis@yahoo.com.br Hypotensive Response to Continuous Aerobic and High-Intensity Interval Exercise Matched by Volume in Sedentary Subjects Francesco Pinto Boeno,1,2 Thiago Rozales Ramis,2 Juliano Boufleur Farinha,2 Cesar Moritz,2 Vagner Pereira dos Santos,1 Alvaro Reischak de Oliveira,2 Bruno Costa Teixeira1 Universidade Regional Integrada do Alto Uruguai e das Missões (URI),1 São Luiz Gonzaga, RS Brazil Universidade Federal do Rio Grande do Sul (UFRS),2 Porto Alegre, RS Brazil

Cardiorespiratory responses of a dance session designed for older women: A cross sectional study

Background: Dancing has been increasingly used as a type of exercise intervention to improve cardiovascular fitness of older people. However, it is unclear which may be the exercise intensity of the dance sessions. Objective: To describe cardiorespiratory responses of a dance session for older women, and to identify intensity zones in relation to peak oxygen consumption (VO2peak), first and second ventilatory thresholds (VT1 and VT2). Methods: Ten women (66 ± 5 yrs., BMI 27 ± 4) were examined on three occasions: Familiarization, maximum effort and dance sessions. Incremental treadmill test: 5 km/h, 2% slope each min, until maximum effort. Dance class (60 min): warm‐up (20 min), across‐the‐floor (10 min), choreography (15 min), show (10 min) and cool‐down (5 min). Ventilatory parameters were measured continuously (breath‐by‐breath). Results: VO2 (mL·kg−1·min−1): Maximum effort: VO2peak (23.3 ± 4.3), VT1 (17.2 ± 3.5) and VT2 (20.9 ± 3.4). Dancing: warm‐up (12.8 ± 2.4, ˜55%VO2peak), across‐the‐floor (14.2 ± 2.4 ˜62%VO2peak), choreography (14.6 ± 3.2 ˜63%VO2peak) and show (16.1 ± 3.3, ˜69% VO2peak). Show was similar to VT1. Conclusions: Cardiorespiratory demands of a dance class for older women are at low aerobic intensity. Show was similar to VT1, indicating that a dance class may be modulated to improve aerobic fitness, at least at initial stages of training. HighlightsCardiorespiratory demands of dancing for older women are at low aerobic intensity.The show part (choreography learned) was similar to the first ventilatory threshold.The show may be manipulated (exercise/rest) for developing aerobic conditioning.Dancing may be a potential exercise for improving cardiovascular health with aging.