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Dive into the research topics where Paula A. R. Tavares is active.

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Featured researches published by Paula A. R. Tavares.


Organic and Biomolecular Chemistry | 2007

A highly effective one-pot synthesis of quinolines from o-nitroarylcarbaldehydes.

An-Hu Li; Eilaf Ahmed; Xin Chen; Matthew Cox; Andrew P. Crew; Hanqing Dong; Meizhong Jin; Lifu Ma; Bijoy Panicker; Kam W. Siu; Arno G. Steinig; Kathryn M. Stolz; Paula A. R. Tavares; Brian Volk; Qinghua Weng; Doug Werner; Mark J. Mulvihill

A highly effective one-pot Friedländer quinoline synthesis using inexpensive reagents has been developed. o-Nitroarylcarbaldehydes were reduced to o-aminoarylcarbaldehydes with iron in the presence of catalytic HCl (aq.) and subsequently condensed in situ with aldehydes or ketones to form mono- or di-substituted quinolines in high yields (66-100%).


Archive | 2006

Fused bicyclic mtor inhibitors

Xin Chen; Heather Coate; Andrew Philip Crew; Hanqing Dong; Ayako Honda; Mark J. Mulvihill; Paula A. R. Tavares; Jing Wang; Douglas S. Werner; Kristen Michelle Mulvihill; Kam W. Siu; Bijoy Panicker; Apoorba Bharadwaj; Lee D. Arnold; Meizhong Jin; Brian Volk; Quinghua Weng; James David Beard


Archive | 2005

Aryl-amino substituted pyrrolopyrimidine multi-kinase inhibiting compounds

Saleh Ahmed; Oscar Barba; Jason Bloxham; Graham Dawson; William Gattrell; John Kitchin; Neil Anthony Pegg; Imaad Saba; Shazia Sadiq; Smith Colin Peter Sambrook; Don Smyth; Arno G. Steinig; Robin Wilkes; Kenneth Foreman; Qinghua Felix Weng; Kathryn M. Stolz; Paula A. R. Tavares; Bijoy Panicker; An-Hu Li; Hanqing Dong; Lifu Ma; Matthew Cox


Bioorganic & Medicinal Chemistry | 2008

Novel 2-phenylquinolin-7-yl-derived imidazo[1,5-a]pyrazines as potent insulin-like growth factor-I receptor (IGF-IR) inhibitors

Mark J. Mulvihill; Qun-Sheng Ji; Heather Coate; Andrew Cooke; Hanqing Dong; Lixin Feng; Kenneth Foreman; Maryland Rosenfeld-Franklin; Ayako Honda; Gilda Mak; Kristen Michelle Mulvihill; Anthony Nigro; Matthew O’Connor; Caroline Pirrit; Arno G. Steinig; Kam W. Siu; Kathryn M. Stolz; Yingchuan Sun; Paula A. R. Tavares; Yan Yao; Neil W. Gibson


Archive | 2007

UNSATURATED mTOR INHIBITORS

Andrew Philip Crew; Douglas S. Werner; Paula A. R. Tavares


Archive | 2011

Fused bicyclic motor inhibitors

Xin Chen; Heather Coate; Andrew Philip Crew; Hanqing Dong; Ayako Honda; Mark J. Mulvihill; Paula A. R. Tavares; Jing Wang; Douglas S. Werner; Kam W. Siu; Bijoy Panicker; Apoorba Bharadwaj; Lee D. Arnold; Meizhong Jin; Brian Volk; Quinghua Weng; James David Beard


Archive | 2006

Intermediates for the preparation of fused bicyclic mTOR inhibitors

Xin Chen; Heather Coate; Andrew-Philip Crew; Hanqing Dong; Ayako Honda; Mark J. Mulvihill; Paula A. R. Tavares; Jing Wang; Douglas S. Werner; Kristen Michelle Mulvihill; Kam W. Siu; Bijoy Panicker; Apoorba Bharadwaj; Lee D. Arnold; Meizhong Jin; Brian Volk; Qinghua Weng; James David Beard


Archive | 2005

Substituted pyrrolo[2.3-B]pyridines

Saleh Ahmed; Oscar Barba; Jason Bloxham; Graham Dawson; William Gattrell; John Kitchin; Neil Anthony Pegg; Imaad Saba; Shazia Sadiq; Colin Peter Sambrook Smith; Don Smyth; Amo G. Steinig; Robin Wilkes; Bijoy Panicker; Paula A. R. Tavares; Matthew Cox; An-Hu Li; Hanqing Dong; Lifu Ma; Kenneth Foreman; Qinghua Weng; Kathryn M. Stolz


Archive | 2007

INHIBITEURS DE mTOR INSATURES

Andrew Philip Crew; Douglas S. Werner; Paula A. R. Tavares


Archive | 2006

Inhibiteurs de mTor bicycliques condensés

Xin Chen; Heather Coate; Andrew-Philip Crew; Hanqing Dong; Ayako Honda; Mark J. Mulvihill; Paula A. R. Tavares; Jing Wang; Douglas S. Werner; Kristen Michelle Mulvihill; Kam W. Siu; Bijoy Panicker; Apoorba Bharadwaj; Lee D. Arnoldd; Meizhong Jin; Brian Volk; Qinghua Weng; James David Beard

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