Roberto Carlos González Álvarez
University of Oviedo
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Learning & Behavior | 1995
Roberto Carlos González Álvarez; Matías Mayor López
The effects of element or compound preexposure and retention interval were examined in three experiments with the taste-aversion paradigm. In Experiment 1, preexposure to the elements of a compound flavor produced less latent inhibition to the compound than did preexposure to the compound itself when a 1-day preexposure-conditioning interval was used. However, preexposing the elements or the compound resulted in equivalent latent inhibition effects when a 21-day retention interval was used. In Experiment 2, a similar pattern of results was observed when the conditioning-test interval was manipulated. Experiment 3 explored the effect of element or compound preexposure when preexposure and test were carried out in different contexts. Attenuated latent inhibition following preexposure to the elements was found when preexposure and test were carried out in the same context. In contrast, preexposure to the elements resulted in as much latent inhibition as did preexposure to the compound when the context was switched from preexposure to testing. The implications of these findings for a retrieval-oriented view of latent inhibition are discussed.
Archivos españoles de urología | 2007
Miguel Álvarez-Múgica; Roberto Carlos González Álvarez; Antonio Jalón Monzón; Jesús María Fernández Gómez; Oscar Rodríguez Faba; Laura Rodríguez Robles; Francisco Javier Regadera Sejas
Resumen es: Objetivo: El objetivo de nuestro estudio, fue valorar la tolerancia por parte del paciente a una biopsia de prostata transrectal ecodirigida usando como ...
Archivos españoles de urología | 2006
Miguel Álvarez Múgica; Antonio Jalón Monzón; Jesús María Fernández Gómez; Juan Javier Rodríguez Martínez; José Luis Martín Benito; Oscar Rodríguez Faba; Roberto Carlos González Álvarez; Laura Rodríguez Robles; Javier Regaderas Sejas; Sawfan Escaf Barmadah
Resumen es: Objetivo: Anadir a la literatura un caso clinico poco frecuente de tumor fibroso solitario pararrenal, analizando las caracteristicas anatomo-patologicas...
Archivos españoles de urología | 2007
Antonio Jalón Monzón; Miguel Álvarez Múgica; Jesús María Fernández Gómez; José Luis Martín Benito; Francisco Javier Martínez Gómez; Jorge García Rodríguez; Roberto Carlos González Álvarez; Francisco Javier Regadera Sejas
OBJETIVOS Valorar el significado pronostico de la clasificacion tumoral TNM de 2002 para el carcinoma de celulas renales (CCR), asi como otros factores implicados en la supervivencia. METODOS Estudio retrospectivo de historias clinicas de 316 carcinomas renales intervenidos entre los anos 1970 y 2003. Se analizaron 25 variables implicadas en el pronostico de pacientes con CCR. RESULTADOS En un 90,5% de pacientes el tipo histologico fue de celulas renales. La mayoria de los tumores fueron T1b o T2, con un grado nuclear de Fuhrman I o II. La media del tamano tumoral fue de 7,17 +/- 3,4 cm. En la mayoria de casos existio tumor unico. En un 8,2% hubo afectacion ganglionar en el momento del diagnostico y en un 8,6% existian metastasis a distancia. La clinica mas frecuente fue hematuria y/o dolor. El seguimiento medio fue de 57,8 meses. Recidivaron un 24,1% de los cuales mas del 50% ocurrio en el primer ano. Los tumores avanzados (T3, T4) tendieron a presentar un grado nuclear III-IV, mayor tamano, necrosis, afectacion vascular, afectacion ganglionar y metastasis a distancia. Al finalizar el seguimiento la mayor parte de pacientes estaba vivo libre de tumor. Los factores que influyeron de forma independiente en la mortalidad cancer especifica fueron los meses libres de enfermedad, la presencia de adenopatias metastasicas, el tratamiento de la primera recidiva y la presencia de anemia. CONCLUSIONES La modificacion de la actual clasificacion de los tumores renales pT3 y pT4, ayudaria a la mejor toma de decisiones en cuanto a la actitud terapeutica de tumores con afectacion vascular, de grasa perirrenal y de glandulas adrenales. La anemia y el tratamiento de la primera recidiva son factores importantes implicados en la supervivencia cancer especifica.
Medicina Clinica | 2009
Jesús María Fernández Gómez; Antonio Jalón Monzón; Miguel Álvarez Múgica; Jorge García Rodríguez; Oscar Miranda Aranzubía; Roberto Carlos González Álvarez
BACKGROUND AND OBJECTIVE The aim of this study was to analyze the significance of anemia as well as other prognostic factors influencing survival in patients with renal cell carcinoma (RCC). PATIENTS AND METHODS A retrospective review of data of 316 patients who underwent surgery between 1970 and 2003 was performed. Most important known prognostic factors of RCC were investigated. RESULTS Most of patients had T1b-T2, low nuclear grade and single tumours. In 8.2% and 9% of cases, lymph node and metastatic dissemination were detected at the time of diagnosis, respectively. At the beginning, most frequent symptoms were hematuria and pain, with anemia (Hb >10g/dl) in 69 patients. After a median follow-up of 50 months, 24.1% of patients had a recurrence. From these, more than 50% developed recurrence within one year after nephrectomy. Advanced tumours (T3-4) consisted of high nuclear grade (III-IV) tumours, larger size tumours, with necrosis and vascular infiltration in surgical specimen, as well as lymph node and metastatic dissemination. In multivariate analysis, anemia, time to recurrence, type of treatment for recurrence as well as lymph node dissemination were independent factors of cancer specific survival. CONCLUSION Anemia seems to be a marker of recurrence and progression in patients with renal cell carcinoma undergoing nephrectomy. From our point of view, anemia could be considered a significantly high mortality rate for renal cancer in these patients.
Archivos españoles de urología | 2008
Antonio Jalón Monzón; Miguel Álvarez Múgica; Verónica Bulnes Vázquez; Roberto Carlos González Álvarez; Jorge García Rodríguez; José Luis Martín Benito; Javier Ferrer Barriendo; Francisco Javier Regadera Sejas
OBJECTIVE: We report one case of ovarian metastasis secondary to a renal clear cell carcinoma. METHODS/RESULTS: 52 year-old consulting for metrorrhagia with the initial diagnosis of primary ovarian carcinoma. Tumor dissemination work up tests reported a renal mass suggestive of ovarian metastasis. Surgery included hysterectomy, double annexectomy, and radical nephrectomy. Final diagnosis was renal clear cell carcinoma with ovarian metastasis. CONCLUSIONS: Metastases to the ovary pose a diagnostic problem in their interpretation, especially when they show a similar histology to the primary ovarian tumor. Due to therapeutic and prognostic implications, it is very important to differentiate if it is a primary ovarian tumor or a metastasis from a renal carcinoma.
Archivos españoles de urología | 2006
Antonio Jalón Monzón; Miguel Álvarez Múgica; Miguel Ángel Seco Navedo; Jesús María Fernández Gómez; Verónica Bulnes Vázquez; Roberto Carlos González Álvarez; Francisco Javier Martínez Gómez; Francisco Javier Regadera Sejas
Resumen en: Objective: The aim of this case report is to add to the literature a new case of renal actinomycosis, but with a form of presentation that has never been...
Archivos españoles de urología | 2005
Antonio Jalón Monzón; Jesús María Fernández Gómez; Oscar Rodríguez Faba; Jorge García Rodríguez; Juan Javier Rodríguez Martínez; Roberto Carlos González Álvarez; Miguel Álvarez Múgica; Francisco Javier Regadera Sejas
Resumen es: OBJETIVOS: Evaluar el impacto de los sintomas del tracto urinario inferior (STUI) referidos en el cuestionario IPSS sobre la calidad de vida y determinar...
Archivos españoles de urología | 2005
Oscar Rodríguez Faba; Alfonso San Martín Blanco; Antonio Jalón Monzón; Roberto Carlos González Álvarez; Miguel Álvarez Mújica; Jesús Mª Fernández Gómez; José Luis Martín Benito; Safwan Escaf Barmadah; Javier Regadera Sejas
Resumen es: OBJETIVO: Determinar la efectividad de las inyecciones endoscopicas en la correccion de la IUE, valorando su escasa agresividad y su impacto positivo en ...
Archivos españoles de urología | 2006
Antonio Jalón Monzón; Alfonso San Martín Blanco; Jorge García Rodríguez; José Luis Martín Benito; Oscar Rodríguez Faba; Roberto Carlos González Álvarez; Miguel Álvarez Múgica; Laura Rodríguez Robles; Francisco Javier Regadera Sejas
Resumen es: Objetivo: La sifilis es una enfermedad sistemica que cursa en estadios clinicos sucesivos. La afectacion del sistema nervioso central y de la medula espi...